Αλκοολισμός
1. Alcohol use 21 August 2024 , WHO
https://www.who.int/europe/news-room/fact-sheets/item/alcohol-use
2. Εθνικό Ινστιτούτο των Η.Π.Α. για την Κατάχρηση Αλκοόλ και τον Αλκοολισμό, Understanding Alcohol Use Disorder
https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/understanding-alcohol-use-disorder
3. Zhu, H.; Xing, Y.; Akan, O.D.; Yang, T. Alcohol-Induced Headache with Neuroinflammation: Recent Progress. Fermentation 2023, 9, 184. https://doi.org/10.3390/fermentation9020184
https://www.mdpi.com/2311-5637/9/2/184
4..Review Article Originally Published 9 June 2025 Free Access Alcohol Use and Cardiovascular Disease: A Scientific Statement From the American Heart Association Mariann R. Piano, RN, PhD, FAHA, Chair, Gregory M. Marcus, MD, FAHA, Vice Chair, Dawn M. Aycock, PhD, RN, FAHA, Jennifer Buckman, PhD, Chueh-Lung Hwang, PhD, PT, Susanna C. Larsson, PhD, Kenneth J. Mukamal, MD, MPH, FAHA, and Michael Roerecke
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001341
Αιμορροΐδες
1. Kibret AA, Oumer M, Moges AM. Prevalence and associated factors of hemorrhoids among adult patients visiting the surgical outpatient department in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. PLoS One. 2021 Apr 20;16(4):e0249736. doi: 10.1371/journal.pone.0249736. PMID: 33878128; PMCID: PMC8057569.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8057569/
2. April 26, 2017 5 Top Hemorrhoids Myths –And the Truth about Treatment, Indiana University
https://iuhealth.org/thrive/5-top-hemorrhoids-myths-and-the-truth-about-treatment
3. Hong, Y.S., Jung, K.U., Rampal, S. et al. Risk factors for hemorrhoidal disease among healthy young and middle-aged Korean adults. Sci Rep 12, 129 (2022). https://doi.org/10.1038/s41598-021-03838-z
https://www.nature.com/articles/s41598-021-03838-z
Διαταραχή Αυτιστικού Φάσματος
1. Bell V, Ferrão J, Chaquisse E, Manuel B and Fernandes T. Role of Mushrooms in Autism. Austin J Nutri Food Sci. 2019; 7(6): 1128.
https://www.researchgate.net/publication/336134611_Role_of_Mushrooms_in_Autism
2. Tang W, Gao Y, Chen G, Gao H, Dai X, Ye J, Chan E, Huang M, Zhou S. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. J Med Food. 2005 Spring;8(1):53-8. doi: 10.1089/jmf.2005.8.53. PMID: 15857210.
https://pubmed.ncbi.nlm.nih.gov/15857210/
3. Sabaratnam V, Kah-Hui W, Naidu M, Rosie David P. Neuronal health - can culinary and medicinal mushrooms help? J Tradit Complement Med. 2013 Jan;3(1):62-8. doi: 10.4103/2225-4110.106549. PMID: 24716157; PMCID: PMC3924982.
https://pubmed.ncbi.nlm.nih.gov/24716157/
4. Zhang X, Wang M, Qiao Y, Shan Z, Yang M, Li G, Xiao Y, Wei L, Bi H, Gao T. Exploring the mechanisms of action of Cordyceps sinensis for the treatment of depression using network pharmacology and molecular docking. Ann Transl Med. 2022 Mar;10(6):282. doi: 10.21037/atm-22-762. PMID: 35434037; PMCID: PMC9011256.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011256/
5. Lee GA, Zhao HW, Chang YW, Lee CJ, Yang YSH, Wu YC, Lin WL, Liu YR, Ning DS, Tseng SH. KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring. Front Pharmacol. 2022 Aug 25;13:964255. doi: 10.3389/fphar.2022.964255. PMID: 36091751; PMCID: PMC9453593.
https://pubmed.ncbi.nlm.nih.gov/36091751/
6. Lee GA, Zhao HW, Chang YW, et al. KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring. Frontiers in Pharmacology. 2022 ;13:964255. DOI: 10.3389/fphar.2022.964255. PMID: 36091751; PMCID: PMC9453593.
https://europepmc.org/article/PMC/5448044
A1. Modabbernia A, Velthorst E, Reichenberg A. Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses. Molecular Autism. 2017 ;8:13. DOI: 10.1186/s13229-017-0121-4. PMID: 28331572; PMCID: PMC5356236.
https://europepmc.org/article/MED/28331572
A2. Rossignol DA, Frye RE. Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis. Molecular Psychiatry. 2012 Mar;17(3):290-314. DOI: 10.1038/mp.2010.136. PMID: 21263444; PMCID: PMC3285768.
https://europepmc.org/article/MED/21263444
A3. Karhu E, Zukerman R, Eshraghi RS, Mittal J, Deth RC, Castejon AM, Trivedi M, Mittal R, Eshraghi AA. Nutritional interventions for autism spectrum disorder. Nutr Rev. 2020 Jul 1;78(7):515-531. doi: 10.1093/nutrit/nuz092. PMID: 31876938.
https://pubmed.ncbi.nlm.nih.gov/31876938/
A4. Adams JB, Audhya T, Geis E, et al. Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder-A Randomized, Controlled 12-Month Trial. Nutrients. 2018 Mar;10(3):E369. DOI: 10.3390/nu10030369. PMID: 29562612; PMCID: PMC5872787.
https://europepmc.org/article/MED/29562612
A5. Fraguas D, Díaz-Caneja CM, Pina-Camacho L, Moreno C, Durán-Cutilla M, Ayora M, González-Vioque E, de Matteis M, Hendren RL, Arango C, Parellada M. Dietary Interventions for Autism Spectrum Disorder: A Meta-analysis. Pediatrics. 2019 Nov;144(5):e20183218. doi: 10.1542/peds.2018-3218. Epub 2019 Oct 4. PMID: 31586029.
https://publications.aap.org/pediatrics/article/144/5/e20183218/76995/Dietary-Interventions-for-Autism-Spectrum-Disorder?autologincheck=redirected?nfToken=00000000-0000-0000-0000-000000000000
A6. Kawicka A, Regulska-Ilow B. How nutritional status, diet and dietary supplements can affect autism. A review. Rocz Panstw Zakl Hig. 2013;64(1):1-12. PMID: 23789306.
https://pubmed.ncbi.nlm.nih.gov/23789306/
A7. Sharma SR, Gonda X, Tarazi FI. Autism Spectrum Disorder: Classification, diagnosis and therapy. Pharmacol Ther. 2018 Oct;190:91-104. doi: 10.1016/j.pharmthera.2018.05.007. Epub 2018 May 12. PMID: 29763648.
https://pubmed.ncbi.nlm.nih.gov/29763648/
A8. Bjørklund G, Waly MI, Al-Farsi Y, Saad K, Dadar M, Rahman MM, Elhoufey A, Chirumbolo S, Jóźwik-Pruska J, Kałużna-Czaplińska J. The Role of Vitamins in Autism Spectrum Disorder: What Do We Know? J Mol Neurosci. 2019 Mar;67(3):373-387. doi: 10.1007/s12031-018-1237-5. Epub 2019 Jan 3. PMID: 30607900.
https://pubmed.ncbi.nlm.nih.gov/30607900/
A9. Golnik, A.E., Ireland, M. Complementary Alternative Medicine for Children with Autism: A Physician Survey. J Autism Dev Disord 39, 996–1005 (2009). https://doi.org/10.1007/s10803-009-0714-7
https://link.springer.com/article/10.1007/s10803-009-0714-7#citeas
A10. Caparros-Gonzalez RA, Torre-Luque A, Romero-Gonzalez B, Quesada-Soto JM, Alderdice F, Peralta-Ramírez MI. Stress During Pregnancy and the Development of Diseases in the offspring: A Systematic-Review and Meta-Analysis. Midwifery. 2021 Jun;97:102939. doi: 10.1016/j.midw.2021.102939. Epub 2021 Feb 23. PMID: 33647755.
https://pubmed.ncbi.nlm.nih.gov/33647755/
Β1. Millward C, Ferriter M, Calver S, Connell-Jones G. Gluten- and casein-free diets for autistic spectrum disorder. Cochrane Database Syst Rev. 2004;(2):CD003498. doi: 10.1002/14651858.CD003498.pub2. Update in: Cochrane Database Syst Rev. 2008;(2):CD003498. PMID: 15106205.
https://pubmed.ncbi.nlm.nih.gov/15106205/
Β2. Elder JH, Shankar M, Shuster J, Theriaque D, Burns S, Sherrill L. The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial. J Autism Dev Disord. 2006 Apr;36(3):413-20. doi: 10.1007/s10803-006-0079-0. PMID: 16555138.
https://pubmed.ncbi.nlm.nih.gov/16555138/
Β3. Millward C, Ferriter M, Calver SJ, Connell-Jones GG. WITHDRAWN: Gluten- and casein-free diets for autistic spectrum disorder. The Cochrane Database of Systematic Reviews. 2019 Apr;4:CD003498. DOI: 10.1002/14651858.cd003498.pub4. PMID: 30938835; PMCID: PMC6445047.
https://europepmc.org/article/MED/30938835
Β4. Keller A, Rimestad ML, Friis Rohde J, Holm Petersen B, Bruun Korfitsen C, Tarp S, Briciet Lauritsen M, Händel MN. The Effect of a Combined Gluten- and Casein-Free Diet on Children and Adolescents with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis. Nutrients. 2021 Jan 30;13(2):470. doi: 10.3390/nu13020470. PMID: 33573238; PMCID: PMC7912271.
https://pubmed.ncbi.nlm.nih.gov/33573238/
Β5. Quan L, Xu X, Cui Y, Han H, Hendren RL, Zhao L, You X. A systematic review and meta-analysis of the benefits of a gluten-free diet and/or casein-free diet for children with autism spectrum disorder. Nutr Rev. 2022 Apr 8;80(5):1237-1246. doi: 10.1093/nutrit/nuab073. PMID: 34617108; PMCID: PMC8990762.
https://pubmed.ncbi.nlm.nih.gov/34617108/
Β6. Yu Y, Huang J, Chen X, Fu J, Wang X, Pu L, Gu C, Cai C. Efficacy and Safety of Diet Therapies in Children With Autism Spectrum Disorder: A Systematic Literature Review and Meta-Analysis. Front Neurol. 2022 Mar 14;13:844117. doi: 10.3389/fneur.2022.844117. PMID: 35359629; PMCID: PMC8963985.
https://pubmed.ncbi.nlm.nih.gov/35359629/
Β7. Lerner A, O'Bryan T, Matthias T. Navigating the Gluten-Free Boom: The Dark Side of Gluten Free Diet. Front Pediatr. 2019 Oct 15;7:414. doi: 10.3389/fped.2019.00414. PMID: 31681712; PMCID: PMC6803387.
https://pubmed.ncbi.nlm.nih.gov/31681712/
Δερματικές παθήσεις
1. Fuchs SM, Heinemann C, Schliemann-Willers S, Härtl H, Fluhr JW, Elsner P. Assessment of anti-inflammatory activity of Poria cocos in sodium lauryl sulphate-induced irritant contact dermatitis. Skin Res Technol. 2006 Nov;12(4):223-7. doi: 10.1111/j.0909-752X.2006.00168.x. PMID: 17026651.
https://pubmed.ncbi.nlm.nih.gov/17026651/
2. Healing Mushrooms: Effective Treatments for Today's Illnesses Εξώφυλλο Georges M. Halpern Square One, 15 Ιαν 2007 - 192 σελίδες
https://books.google.gr/books?id=FlrpouUh740C&pg=PA118&lpg=PA118&dq=poria+cocos&source=bl&ots=XEm44Iwr5m&sig=ACfU3U3PAMeli-sdtjLo3NgafjxvJwQmUw&hl=el&sa=X&ved=2ahUKEwiJibGCwMXqAhXTtHEKHZx3BX44FBDoATAGegQIChAB#v=onepage&q=poria%20cocos&f=false
Ηπατίτιδα c
Grinde B, Hetland G, Johnson E. Effects on gene expression and viral load of a medicinal extract from Agaricus blazei in patients with chronic hepatitis C infection. Int Immunopharmacol. 2006 Aug;6(8):1311-4. doi: 10.1016/j.intimp.2006.04.005. Epub 2006 May 11. PMID: 16782544.
https://pubmed.ncbi.nlm.nih.gov/16782544/
Επιχείλιος έρπης
1. Eo SK, Kim YS, Lee CK, Han SS. Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses. J Ethnopharmacol. 2000 Oct;72(3):475-81. doi: 10.1016/s0378-8741(00)00266-x. PMID: 10996289.
https://pubmed.ncbi.nlm.nih.gov/10996289/
2. Liu J, Yang F, Ye LB, Yang XJ, Timani KA, Zheng Y, Wang YH. Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro. J Ethnopharmacol. 2004 Dec;95(2-3):265-72. doi: 10.1016/j.jep.2004.07.010. PMID: 15507347.
https://pubmed.ncbi.nlm.nih.gov/15507347/
3.Kim YS, Eo SK, Oh KW, Lee C, Han SS. Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with interferons. J Ethnopharmacol. 2000 Oct;72(3):451-8. doi: 10.1016/s0378-8741(00)00263-4. PMID: 10996285.
https://pubmed.ncbi.nlm.nih.gov/10996285/
4. Oh KW, Lee CK, Kim YS, Eo SK, Han SS. Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with acyclovir and vidarabine. J Ethnopharmacol. 2000 Sep;72(1-2):221-7. doi: 10.1016/s0378-8741(00)00254-3. PMID: 10967475.
https://pubmed.ncbi.nlm.nih.gov/10967475/
5.Eo SK, Kim YS, Lee CK, Han SS. Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum. J Ethnopharmacol. 1999 Dec 15;68(1-3):175-81. doi: 10.1016/s0378-8741(99)00086-0. PMID: 10624876.
https://pubmed.ncbi.nlm.nih.gov/10624876/
6.Eo SK, Kim YS, Lee CK, Han SS. Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum. J Ethnopharmacol. 1999 Dec 15;68(1-3):129-36. doi: 10.1016/s0378-8741(99)00067-7. PMID: 10624872.
https://pubmed.ncbi.nlm.nih.gov/10624872/
7. Razumov IA, Kosogova TA, Kazachinskaia EI, Puchkova LI, Shcherbakova NS, Gorbunova IA, Mikhaĭlovskaia IN, Loktev VB, Tepliakova TV. [Antiviral activity of aqueous extracts and polysaccharide fractions from mycelium and fruit bodies of higher fungi]. Antibiot Khimioter. 2010;55(9-10):14-8. Russian. PMID: 21400748.
https://pubmed.ncbi.nlm.nih.gov/21400748/
8. Hijikata Y, Yamada S. Effect of Ganoderma lucidum on postherpetic neuralgia. Am J Chin Med. 1998;26(3-4):375-81. doi: 10.1142/S0192415X98000415. PMID: 9862025.
https://pubmed.ncbi.nlm.nih.gov/9862025/
Οστεοπόρωση
1. Erjavec I, Brkljacic J, Vukicevic S, Jakopovic B, Jakopovich I. Mushroom Extracts Decrease Bone Resorption and Improve Bone Formation. Int J Med Mushrooms. 2016;18(7):559-69. doi: 10.1615/intjmedmushrooms.v18.i7.10. PMID: 27649725.
https://pubmed.ncbi.nlm.nih.gov/27649725/
2. Lindequist U, Haertel B. Medicinal Mushrooms for Prevention and Therapy of Osteoporosis (Review). Int J Med Mushrooms. 2021;23(4):13-22. doi: 10.1615/IntJMedMushrooms.2021038084. PMID: 33822504.
https://pubmed.ncbi.nlm.nih.gov/33822504/
3. Lee Hyerim, Hyun Tae Kyung, Yi Sun-Ju, Kim Kyunghwan. Effects of shiitake mushroom stipe extracts on osteoclast differentiation and bone health. J Biomed Transl Res 2025;26(1):1-10.
https://www.jbtr.or.kr/archive/view_article?pid=jbtr-26-1-1
4. Cicha-Jeleń, M.; Kała, K.; Sułkowska-Ziaja, K.; Muszyńska, B. The Significance of a Mushroom Diet in the Prevention of Osteoporosis. Pharmaceuticals 2026, 19, 482. https://doi.org/10.3390/ph19030482
https://www.mdpi.com/1424-8247/19/3/482
5. Kerezoudi EN, Mitsou EK, Gioti K, Terzi E, Avgousti I, Panagiotou A, Koutrotsios G, Zervakis GI, Mountzouris KC, Tenta R, Kyriacou A. Fermentation of Pleurotus ostreatus and Ganoderma lucidum mushrooms and their extracts by the gut microbiota of healthy and osteopenic women: potential prebiotic effect and impact of mushroom fermentation products on human osteoblasts. Food Funct. 2021 Mar 1;12(4):1529-1546. doi: 10.1039/d0fo02581j. PMID: 33521800.
https://pubmed.ncbi.nlm.nih.gov/33521800/
6. Oyster Mushroom Can Reduce Osteoporosis Risks News Report 3 August 2016, 15.54, universitas gadjah mada
https://ugm.ac.id/en/news/12202-oyster-mushroom-can-reduce-osteoporosis-risks/
Προστασία DNA
1. γονοτοξικότητα, EFSA,
https://www.efsa.europa.eu/el/glossary/genotoxicity
2. Phillips DH, Arlt VM. Genotoxicity: damage to DNA and its consequences. EXS. 2009;99:87-110. doi: 10.1007/978-3-7643-8336-7_4. PMID: 19157059.
https://pubmed.ncbi.nlm.nih.gov/19157059/
3. Vasiljevic JD, Zivkovic LP, Cabarkapa AM, Bajic VP, Djelic NJ, Spremo-Potparevic BM. Cordyceps sinensis: Genotoxic Potential in Human Peripheral Blood Cells and Antigenotoxic Properties Against Hydrogen Peroxide by Comet Assay. Altern Ther Health Med. 2016 Jun;22 Suppl 2:24-31. PMID: 27433838.
https://pubmed.ncbi.nlm.nih.gov/27433838/
Προστασία με δηλητηρίαση από Russula subnigricans
Xiao GL, Liu FY, Chen ZH. [Clinical observation on treatment of Russula subnigricans poisoning patients by Ganoderma lucidum decoction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine. 2003 Apr;23(4):278-280. PMID: 12764911.
https://europepmc.org/article/med/12764911
1. Alcohol use 21 August 2024 , WHO
https://www.who.int/europe/news-room/fact-sheets/item/alcohol-use
2. Εθνικό Ινστιτούτο των Η.Π.Α. για την Κατάχρηση Αλκοόλ και τον Αλκοολισμό, Understanding Alcohol Use Disorder
https://www.niaaa.nih.gov/publications/brochures-and-fact-sheets/understanding-alcohol-use-disorder
3. Zhu, H.; Xing, Y.; Akan, O.D.; Yang, T. Alcohol-Induced Headache with Neuroinflammation: Recent Progress. Fermentation 2023, 9, 184. https://doi.org/10.3390/fermentation9020184
https://www.mdpi.com/2311-5637/9/2/184
4..Review Article Originally Published 9 June 2025 Free Access Alcohol Use and Cardiovascular Disease: A Scientific Statement From the American Heart Association Mariann R. Piano, RN, PhD, FAHA, Chair, Gregory M. Marcus, MD, FAHA, Vice Chair, Dawn M. Aycock, PhD, RN, FAHA, Jennifer Buckman, PhD, Chueh-Lung Hwang, PhD, PT, Susanna C. Larsson, PhD, Kenneth J. Mukamal, MD, MPH, FAHA, and Michael Roerecke
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001341
Αιμορροΐδες
1. Kibret AA, Oumer M, Moges AM. Prevalence and associated factors of hemorrhoids among adult patients visiting the surgical outpatient department in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. PLoS One. 2021 Apr 20;16(4):e0249736. doi: 10.1371/journal.pone.0249736. PMID: 33878128; PMCID: PMC8057569.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8057569/
2. April 26, 2017 5 Top Hemorrhoids Myths –And the Truth about Treatment, Indiana University
https://iuhealth.org/thrive/5-top-hemorrhoids-myths-and-the-truth-about-treatment
3. Hong, Y.S., Jung, K.U., Rampal, S. et al. Risk factors for hemorrhoidal disease among healthy young and middle-aged Korean adults. Sci Rep 12, 129 (2022). https://doi.org/10.1038/s41598-021-03838-z
https://www.nature.com/articles/s41598-021-03838-z
Διαταραχή Αυτιστικού Φάσματος
1. Bell V, Ferrão J, Chaquisse E, Manuel B and Fernandes T. Role of Mushrooms in Autism. Austin J Nutri Food Sci. 2019; 7(6): 1128.
https://www.researchgate.net/publication/336134611_Role_of_Mushrooms_in_Autism
2. Tang W, Gao Y, Chen G, Gao H, Dai X, Ye J, Chan E, Huang M, Zhou S. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. J Med Food. 2005 Spring;8(1):53-8. doi: 10.1089/jmf.2005.8.53. PMID: 15857210.
https://pubmed.ncbi.nlm.nih.gov/15857210/
3. Sabaratnam V, Kah-Hui W, Naidu M, Rosie David P. Neuronal health - can culinary and medicinal mushrooms help? J Tradit Complement Med. 2013 Jan;3(1):62-8. doi: 10.4103/2225-4110.106549. PMID: 24716157; PMCID: PMC3924982.
https://pubmed.ncbi.nlm.nih.gov/24716157/
4. Zhang X, Wang M, Qiao Y, Shan Z, Yang M, Li G, Xiao Y, Wei L, Bi H, Gao T. Exploring the mechanisms of action of Cordyceps sinensis for the treatment of depression using network pharmacology and molecular docking. Ann Transl Med. 2022 Mar;10(6):282. doi: 10.21037/atm-22-762. PMID: 35434037; PMCID: PMC9011256.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9011256/
5. Lee GA, Zhao HW, Chang YW, Lee CJ, Yang YSH, Wu YC, Lin WL, Liu YR, Ning DS, Tseng SH. KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring. Front Pharmacol. 2022 Aug 25;13:964255. doi: 10.3389/fphar.2022.964255. PMID: 36091751; PMCID: PMC9453593.
https://pubmed.ncbi.nlm.nih.gov/36091751/
6. Lee GA, Zhao HW, Chang YW, et al. KI Essence extract (a spleen-tonifying formula) promotes neurite outgrowth, alleviates oxidative stress and hypomyelination, and modulates microbiome in maternal immune activation offspring. Frontiers in Pharmacology. 2022 ;13:964255. DOI: 10.3389/fphar.2022.964255. PMID: 36091751; PMCID: PMC9453593.
https://europepmc.org/article/PMC/5448044
A1. Modabbernia A, Velthorst E, Reichenberg A. Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses. Molecular Autism. 2017 ;8:13. DOI: 10.1186/s13229-017-0121-4. PMID: 28331572; PMCID: PMC5356236.
https://europepmc.org/article/MED/28331572
A2. Rossignol DA, Frye RE. Mitochondrial dysfunction in autism spectrum disorders: a systematic review and meta-analysis. Molecular Psychiatry. 2012 Mar;17(3):290-314. DOI: 10.1038/mp.2010.136. PMID: 21263444; PMCID: PMC3285768.
https://europepmc.org/article/MED/21263444
A3. Karhu E, Zukerman R, Eshraghi RS, Mittal J, Deth RC, Castejon AM, Trivedi M, Mittal R, Eshraghi AA. Nutritional interventions for autism spectrum disorder. Nutr Rev. 2020 Jul 1;78(7):515-531. doi: 10.1093/nutrit/nuz092. PMID: 31876938.
https://pubmed.ncbi.nlm.nih.gov/31876938/
A4. Adams JB, Audhya T, Geis E, et al. Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder-A Randomized, Controlled 12-Month Trial. Nutrients. 2018 Mar;10(3):E369. DOI: 10.3390/nu10030369. PMID: 29562612; PMCID: PMC5872787.
https://europepmc.org/article/MED/29562612
A5. Fraguas D, Díaz-Caneja CM, Pina-Camacho L, Moreno C, Durán-Cutilla M, Ayora M, González-Vioque E, de Matteis M, Hendren RL, Arango C, Parellada M. Dietary Interventions for Autism Spectrum Disorder: A Meta-analysis. Pediatrics. 2019 Nov;144(5):e20183218. doi: 10.1542/peds.2018-3218. Epub 2019 Oct 4. PMID: 31586029.
https://publications.aap.org/pediatrics/article/144/5/e20183218/76995/Dietary-Interventions-for-Autism-Spectrum-Disorder?autologincheck=redirected?nfToken=00000000-0000-0000-0000-000000000000
A6. Kawicka A, Regulska-Ilow B. How nutritional status, diet and dietary supplements can affect autism. A review. Rocz Panstw Zakl Hig. 2013;64(1):1-12. PMID: 23789306.
https://pubmed.ncbi.nlm.nih.gov/23789306/
A7. Sharma SR, Gonda X, Tarazi FI. Autism Spectrum Disorder: Classification, diagnosis and therapy. Pharmacol Ther. 2018 Oct;190:91-104. doi: 10.1016/j.pharmthera.2018.05.007. Epub 2018 May 12. PMID: 29763648.
https://pubmed.ncbi.nlm.nih.gov/29763648/
A8. Bjørklund G, Waly MI, Al-Farsi Y, Saad K, Dadar M, Rahman MM, Elhoufey A, Chirumbolo S, Jóźwik-Pruska J, Kałużna-Czaplińska J. The Role of Vitamins in Autism Spectrum Disorder: What Do We Know? J Mol Neurosci. 2019 Mar;67(3):373-387. doi: 10.1007/s12031-018-1237-5. Epub 2019 Jan 3. PMID: 30607900.
https://pubmed.ncbi.nlm.nih.gov/30607900/
A9. Golnik, A.E., Ireland, M. Complementary Alternative Medicine for Children with Autism: A Physician Survey. J Autism Dev Disord 39, 996–1005 (2009). https://doi.org/10.1007/s10803-009-0714-7
https://link.springer.com/article/10.1007/s10803-009-0714-7#citeas
A10. Caparros-Gonzalez RA, Torre-Luque A, Romero-Gonzalez B, Quesada-Soto JM, Alderdice F, Peralta-Ramírez MI. Stress During Pregnancy and the Development of Diseases in the offspring: A Systematic-Review and Meta-Analysis. Midwifery. 2021 Jun;97:102939. doi: 10.1016/j.midw.2021.102939. Epub 2021 Feb 23. PMID: 33647755.
https://pubmed.ncbi.nlm.nih.gov/33647755/
Β1. Millward C, Ferriter M, Calver S, Connell-Jones G. Gluten- and casein-free diets for autistic spectrum disorder. Cochrane Database Syst Rev. 2004;(2):CD003498. doi: 10.1002/14651858.CD003498.pub2. Update in: Cochrane Database Syst Rev. 2008;(2):CD003498. PMID: 15106205.
https://pubmed.ncbi.nlm.nih.gov/15106205/
Β2. Elder JH, Shankar M, Shuster J, Theriaque D, Burns S, Sherrill L. The gluten-free, casein-free diet in autism: results of a preliminary double blind clinical trial. J Autism Dev Disord. 2006 Apr;36(3):413-20. doi: 10.1007/s10803-006-0079-0. PMID: 16555138.
https://pubmed.ncbi.nlm.nih.gov/16555138/
Β3. Millward C, Ferriter M, Calver SJ, Connell-Jones GG. WITHDRAWN: Gluten- and casein-free diets for autistic spectrum disorder. The Cochrane Database of Systematic Reviews. 2019 Apr;4:CD003498. DOI: 10.1002/14651858.cd003498.pub4. PMID: 30938835; PMCID: PMC6445047.
https://europepmc.org/article/MED/30938835
Β4. Keller A, Rimestad ML, Friis Rohde J, Holm Petersen B, Bruun Korfitsen C, Tarp S, Briciet Lauritsen M, Händel MN. The Effect of a Combined Gluten- and Casein-Free Diet on Children and Adolescents with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis. Nutrients. 2021 Jan 30;13(2):470. doi: 10.3390/nu13020470. PMID: 33573238; PMCID: PMC7912271.
https://pubmed.ncbi.nlm.nih.gov/33573238/
Β5. Quan L, Xu X, Cui Y, Han H, Hendren RL, Zhao L, You X. A systematic review and meta-analysis of the benefits of a gluten-free diet and/or casein-free diet for children with autism spectrum disorder. Nutr Rev. 2022 Apr 8;80(5):1237-1246. doi: 10.1093/nutrit/nuab073. PMID: 34617108; PMCID: PMC8990762.
https://pubmed.ncbi.nlm.nih.gov/34617108/
Β6. Yu Y, Huang J, Chen X, Fu J, Wang X, Pu L, Gu C, Cai C. Efficacy and Safety of Diet Therapies in Children With Autism Spectrum Disorder: A Systematic Literature Review and Meta-Analysis. Front Neurol. 2022 Mar 14;13:844117. doi: 10.3389/fneur.2022.844117. PMID: 35359629; PMCID: PMC8963985.
https://pubmed.ncbi.nlm.nih.gov/35359629/
Β7. Lerner A, O'Bryan T, Matthias T. Navigating the Gluten-Free Boom: The Dark Side of Gluten Free Diet. Front Pediatr. 2019 Oct 15;7:414. doi: 10.3389/fped.2019.00414. PMID: 31681712; PMCID: PMC6803387.
https://pubmed.ncbi.nlm.nih.gov/31681712/
Δερματικές παθήσεις
1. Fuchs SM, Heinemann C, Schliemann-Willers S, Härtl H, Fluhr JW, Elsner P. Assessment of anti-inflammatory activity of Poria cocos in sodium lauryl sulphate-induced irritant contact dermatitis. Skin Res Technol. 2006 Nov;12(4):223-7. doi: 10.1111/j.0909-752X.2006.00168.x. PMID: 17026651.
https://pubmed.ncbi.nlm.nih.gov/17026651/
2. Healing Mushrooms: Effective Treatments for Today's Illnesses Εξώφυλλο Georges M. Halpern Square One, 15 Ιαν 2007 - 192 σελίδες
https://books.google.gr/books?id=FlrpouUh740C&pg=PA118&lpg=PA118&dq=poria+cocos&source=bl&ots=XEm44Iwr5m&sig=ACfU3U3PAMeli-sdtjLo3NgafjxvJwQmUw&hl=el&sa=X&ved=2ahUKEwiJibGCwMXqAhXTtHEKHZx3BX44FBDoATAGegQIChAB#v=onepage&q=poria%20cocos&f=false
Ηπατίτιδα c
Grinde B, Hetland G, Johnson E. Effects on gene expression and viral load of a medicinal extract from Agaricus blazei in patients with chronic hepatitis C infection. Int Immunopharmacol. 2006 Aug;6(8):1311-4. doi: 10.1016/j.intimp.2006.04.005. Epub 2006 May 11. PMID: 16782544.
https://pubmed.ncbi.nlm.nih.gov/16782544/
Επιχείλιος έρπης
1. Eo SK, Kim YS, Lee CK, Han SS. Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses. J Ethnopharmacol. 2000 Oct;72(3):475-81. doi: 10.1016/s0378-8741(00)00266-x. PMID: 10996289.
https://pubmed.ncbi.nlm.nih.gov/10996289/
2. Liu J, Yang F, Ye LB, Yang XJ, Timani KA, Zheng Y, Wang YH. Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro. J Ethnopharmacol. 2004 Dec;95(2-3):265-72. doi: 10.1016/j.jep.2004.07.010. PMID: 15507347.
https://pubmed.ncbi.nlm.nih.gov/15507347/
3.Kim YS, Eo SK, Oh KW, Lee C, Han SS. Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with interferons. J Ethnopharmacol. 2000 Oct;72(3):451-8. doi: 10.1016/s0378-8741(00)00263-4. PMID: 10996285.
https://pubmed.ncbi.nlm.nih.gov/10996285/
4. Oh KW, Lee CK, Kim YS, Eo SK, Han SS. Antiherpetic activities of acidic protein bound polysacchride isolated from Ganoderma lucidum alone and in combinations with acyclovir and vidarabine. J Ethnopharmacol. 2000 Sep;72(1-2):221-7. doi: 10.1016/s0378-8741(00)00254-3. PMID: 10967475.
https://pubmed.ncbi.nlm.nih.gov/10967475/
5.Eo SK, Kim YS, Lee CK, Han SS. Antiherpetic activities of various protein bound polysaccharides isolated from Ganoderma lucidum. J Ethnopharmacol. 1999 Dec 15;68(1-3):175-81. doi: 10.1016/s0378-8741(99)00086-0. PMID: 10624876.
https://pubmed.ncbi.nlm.nih.gov/10624876/
6.Eo SK, Kim YS, Lee CK, Han SS. Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum. J Ethnopharmacol. 1999 Dec 15;68(1-3):129-36. doi: 10.1016/s0378-8741(99)00067-7. PMID: 10624872.
https://pubmed.ncbi.nlm.nih.gov/10624872/
7. Razumov IA, Kosogova TA, Kazachinskaia EI, Puchkova LI, Shcherbakova NS, Gorbunova IA, Mikhaĭlovskaia IN, Loktev VB, Tepliakova TV. [Antiviral activity of aqueous extracts and polysaccharide fractions from mycelium and fruit bodies of higher fungi]. Antibiot Khimioter. 2010;55(9-10):14-8. Russian. PMID: 21400748.
https://pubmed.ncbi.nlm.nih.gov/21400748/
8. Hijikata Y, Yamada S. Effect of Ganoderma lucidum on postherpetic neuralgia. Am J Chin Med. 1998;26(3-4):375-81. doi: 10.1142/S0192415X98000415. PMID: 9862025.
https://pubmed.ncbi.nlm.nih.gov/9862025/
Οστεοπόρωση
1. Erjavec I, Brkljacic J, Vukicevic S, Jakopovic B, Jakopovich I. Mushroom Extracts Decrease Bone Resorption and Improve Bone Formation. Int J Med Mushrooms. 2016;18(7):559-69. doi: 10.1615/intjmedmushrooms.v18.i7.10. PMID: 27649725.
https://pubmed.ncbi.nlm.nih.gov/27649725/
2. Lindequist U, Haertel B. Medicinal Mushrooms for Prevention and Therapy of Osteoporosis (Review). Int J Med Mushrooms. 2021;23(4):13-22. doi: 10.1615/IntJMedMushrooms.2021038084. PMID: 33822504.
https://pubmed.ncbi.nlm.nih.gov/33822504/
3. Lee Hyerim, Hyun Tae Kyung, Yi Sun-Ju, Kim Kyunghwan. Effects of shiitake mushroom stipe extracts on osteoclast differentiation and bone health. J Biomed Transl Res 2025;26(1):1-10.
https://www.jbtr.or.kr/archive/view_article?pid=jbtr-26-1-1
4. Cicha-Jeleń, M.; Kała, K.; Sułkowska-Ziaja, K.; Muszyńska, B. The Significance of a Mushroom Diet in the Prevention of Osteoporosis. Pharmaceuticals 2026, 19, 482. https://doi.org/10.3390/ph19030482
https://www.mdpi.com/1424-8247/19/3/482
5. Kerezoudi EN, Mitsou EK, Gioti K, Terzi E, Avgousti I, Panagiotou A, Koutrotsios G, Zervakis GI, Mountzouris KC, Tenta R, Kyriacou A. Fermentation of Pleurotus ostreatus and Ganoderma lucidum mushrooms and their extracts by the gut microbiota of healthy and osteopenic women: potential prebiotic effect and impact of mushroom fermentation products on human osteoblasts. Food Funct. 2021 Mar 1;12(4):1529-1546. doi: 10.1039/d0fo02581j. PMID: 33521800.
https://pubmed.ncbi.nlm.nih.gov/33521800/
6. Oyster Mushroom Can Reduce Osteoporosis Risks News Report 3 August 2016, 15.54, universitas gadjah mada
https://ugm.ac.id/en/news/12202-oyster-mushroom-can-reduce-osteoporosis-risks/
Προστασία DNA
1. γονοτοξικότητα, EFSA,
https://www.efsa.europa.eu/el/glossary/genotoxicity
2. Phillips DH, Arlt VM. Genotoxicity: damage to DNA and its consequences. EXS. 2009;99:87-110. doi: 10.1007/978-3-7643-8336-7_4. PMID: 19157059.
https://pubmed.ncbi.nlm.nih.gov/19157059/
3. Vasiljevic JD, Zivkovic LP, Cabarkapa AM, Bajic VP, Djelic NJ, Spremo-Potparevic BM. Cordyceps sinensis: Genotoxic Potential in Human Peripheral Blood Cells and Antigenotoxic Properties Against Hydrogen Peroxide by Comet Assay. Altern Ther Health Med. 2016 Jun;22 Suppl 2:24-31. PMID: 27433838.
https://pubmed.ncbi.nlm.nih.gov/27433838/
Προστασία με δηλητηρίαση από Russula subnigricans
Xiao GL, Liu FY, Chen ZH. [Clinical observation on treatment of Russula subnigricans poisoning patients by Ganoderma lucidum decoction]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine. 2003 Apr;23(4):278-280. PMID: 12764911.
https://europepmc.org/article/med/12764911
