Αυτοάνοσες παθήσεις
1. PDQ® Integrative, Alternative, and Complementary Therapies Editorial Board. PDQ Medicinal Mushrooms. Bethesda, MD: National Cancer Institute. Updated  July 11, 2024. Available at: https://www.cancer.gov/about-cancer/treatment/cam/patient/mushrooms-pdq. Accessed 30/12/2025. [PMID: 28267306]

13. Sujogya Kumar Panda, Walter Luyten, Medicinal mushrooms: Clinical perspective and challenges, Drug Discovery Today, Volume 27, Issue 2, 2022, Pages 636-651, ISSN 1359-6446, https://doi.org/10.1016/j.drudis.2021.11.017.
https://www.sciencedirect.com/science/article/abs/pii/S1359644621004980

59. Panda SK, Luyten W. Medicinal mushrooms: Clinical perspective and challenges. Drug Discov Today. 2022 Feb;27(2):636-651. doi: 10.1016/j.drudis.2021.11.017. Epub 2021 Nov 22. PMID: 34823005.
https://pubmed.ncbi.nlm.nih.gov/34823005/

60. Motta F, Gershwin ME, Selmi C. Mushrooms and immunity. J Autoimmun. 2021 Feb;117:102576. doi: 10.1016/j.jaut.2020.102576. Epub 2020 Dec 1. PMID: 33276307.
https://pubmed.ncbi.nlm.nih.gov/33276307/

61. Jeitler M, Michalsen A, Frings D, Hübner M, Fischer M, Koppold-Liebscher DA, Murthy V, Kessler CS. Significance of Medicinal Mushrooms in Integrative Oncology: A Narrative Review. Front Pharmacol. 2020 Nov 11;11:580656. doi: 10.3389/fphar.2020.580656. PMID: 33424591; PMCID: PMC7794004.
https://pubmed.ncbi.nlm.nih.gov/33424591/

62. Dan A, Swain R, Belonce S, Jacobs RJ. Therapeutic Effects of Medicinal Mushrooms on Gastric, Breast, and Colorectal Cancer: A Scoping Review. Cureus. 2023 Apr 14;15(4):e37574. doi: 10.7759/cureus.37574. PMID: 37193480; PMCID: PMC10183216.
https://pubmed.ncbi.nlm.nih.gov/37193480/

63. Phan CW, David P, Sabaratnam V. Edible and Medicinal Mushrooms: Emerging Brain Food for the Mitigation of Neurodegenerative Diseases. J Med Food. 2017 Jan;20(1):1-10. doi: 10.1089/jmf.2016.3740. PMID: 28098514.
https://pubmed.ncbi.nlm.nih.gov/28098514/

64. Zhao S, Gao Q, Rong C, Wang S, Zhao Z, Liu Y, Xu J. Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products. J Fungi (Basel). 2020 Nov 8;6(4):269. doi: 10.3390/jof6040269. PMID: 33171663; PMCID: PMC7712035.
https://pubmed.ncbi.nlm.nih.gov/33171663/

65.  Drzewiecka, B.; Wessely-Szponder, J.; Świeca, M.; Espinal, P.; Fusté, E.; Fernández-De La Cruz, E. Bioactive Peptides and Other Immunomodulators of Mushroom Origin. Biomedicines 2024, 12, 1483.
https://www.mdpi.com/2227-9059/12/7/1483

66. Hetland G, Tangen JM, Mahmood F, Mirlashari MR, Nissen-Meyer LSH, Nentwich I, Therkelsen SP, Tjønnfjord GE, Johnson E. Antitumor, Anti-Inflammatory and Antiallergic Effects of Agaricus blazei Mushroom Extract and the Related Medicinal Basidiomycetes Mushrooms, Hericium erinaceus and Grifolafrondosa: A Review of Preclinical and Clinical Studies. Nutrients. 2020 May 8;12(5):1339. doi: 10.3390/nu12051339. PMID: 32397163; PMCID: PMC7285126.
https://pubmed.ncbi.nlm.nih.gov/32397163/

67. Manash Pratim Pathak, Kalyani Pathak, Riya Saikia, Urvashee Gogoi, Mohammad Zaki Ahmad, Pompy Patowary, Aparoop Das, Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review, Biomedicine & Pharmacotherapy, Volume 149, 2022, 112901, ISSN 0753-3322.
https://www.sciencedirect.com/science/article/pii/S0753332222002906

68. Akramiene D, Kondrotas A, Didziapetriene J, Kevelaitis E. Effects of beta-glucans on the immune system. Medicina (Kaunas). 2007;43(8):597-606. PMID: 17895634.
https://pubmed.ncbi.nlm.nih.gov/17895634/

69. Dong Y, Wang T, Zhao J, Gan B, Feng R, Miao R. Polysaccharides Derived from Mushrooms in Immune and Antitumor Activity: A Review. Int J Med Mushrooms. 2023;25(8):1-17. doi: 10.1615/IntJMedMushrooms.2023049062. PMID: 37560886.
https://pubmed.ncbi.nlm.nih.gov/37560886/

70. Vetvicka V, Vannucci L, Sima P, Richter J. Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials. Molecules. 2019 Mar 30;24(7):1251. doi: 10.3390/molecules24071251. PMID: 30935016; PMCID: PMC6479769.
https://pubmed.ncbi.nlm.nih.gov/30935016/

71.  Do Mushroom Supplements Boost Immunity Against Cancer? By Susan Wagner Tuesday, October 22, 2024, Memorial Sloan Kettering Cancer Center
https://www.mskcc.org/news/do-mushroom-supplements-boost-immunity-against-cancer

72. Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005 Jun 9;2005(2):63-80. doi: 10.1155/MI.2005.63. PMID: 16030389; PMCID: PMC1160565.
https://pmc.ncbi.nlm.nih.gov/articles/PMC1160565/

140. Chugh RM, Mittal P, Mp N, Arora T, Bhattacharya T, Chopra H, Cavalu S, Gautam RK. Fungal Mushrooms: A Natural Compound With Therapeutic Applications. Front Pharmacol. 2022 Jul 13;13:925387. doi: 10.3389/fphar.2022.925387. PMID: 35910346; PMCID: PMC9328747.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9328747/

251. Int J Med Mushrooms, 19 (4), 279-317 2017 Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review Solomon P Wasser
https://pubmed.ncbi.nlm.nih.gov/28605319

252. Biomed J, 37 (6), 345-56 Nov-Dec 2014 Medicinal Mushroom Science: Current Perspectives, Advances, Evidences, and Challenges Solomon P Wasser
https://pubmed.ncbi.nlm.nih.gov/25179726

253. Karthiyayini Balakrishnan, Sanjushree Nagarajan, Gowdhami Balakrishnan, Muthuselvam Manickam, Dhanasekaran Dharumadurai, Chapter 15 - Symbiotic microbial interactions in medicinal mushroom: an insight of phenotypic and genotypic characterization methods, Editor(s): Dhanasekaran Dharumadurai, In Developments in Applied Microbiology and Biotechnology, Microbial Symbionts, Academic Press, 2023, Pages 277-294, ISBN 9780323993340
https://www.sciencedirect.com/topics/immunology-and-microbiology/medicinal-mushroom

254. Fungi as Future Medicine: The Therapeutic Potential of Mushrooms, Dr. Sanchari Sinha Dutta, Ph.D., News-Medical.Net ,
https://www.news-medical.net/health/Fungi-as-Future-Medicine-The-Therapeutic-Potential-of-Mushrooms.aspx

255. Chemical and Pharmacological Investigations of Fomitopsis betulina (formerly: Piptoporus betulinus) and Calvatia gigantea, Inauguraldissertation zur Erlangung des akademischen Grades doctor rerum naturalium (Dr. rer. nat.) an der Mathematisch-Naturwissenschaftlichen Fakultät der Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Februar 2019
https://epub.ub.uni-greifswald.de/frontdoor/deliver/index/docId/3477/file/Dissertation-Alresly.pdf

256. Wasser, Solomon. (2017). Medicinal Properties and Clinical Effects of Medicinal Mushrooms: Technology and Applications. 10.1002/9781119149446.ch22.
https://www.researchgate.net/publication/319118336_Medicinal_Properties_and_Clinical_Effects_of_Medicinal_Mushrooms_Technology_and_Applications



Γρίπη
752. Γρίπη και Εποχική Γρίπη, ΕΟΔΥ.
https://eody.gov.gr/disease/gripi-kai-epochiki-gripi/

753. The Flu: 3 Ways to Fight Back at 50-Plus,  The Johns Hopkins University
https://www.hopkinsmedicine.org/health/conditions-and-diseases/influenza/the-flu-3-ways-to-fight-back-at-50-plus

754. Strengthen your immune system against seasonal illnesses      December 17, 2024     Teresa Saenz
https://vitalrecord.tamu.edu/strengthen-your-immune-system-against-seasonal-illnesses

755. Allen EK, Thomas PG. Immunity to influenza. Preventing infection and regulating disease. Am J Respir Crit Care Med. 2015 Feb 1;191(3):248-51. doi: 10.1164/rccm.201412-2245ED. PMID: 25635487; PMCID: PMC4351582.
https://www.atsjournals.org/doi/full/10.1164/rccm.201412-2245ED

756.  Zhang, Y.; Zhang, G.; Ling, J. Medicinal Fungi with Antiviral Effect. Molecules 2022, 27, 4457. https://doi.org/10.3390/molecules27144457
https://www.mdpi.com/1420-3049/27/14/4457

757. Medicinal Mushrooms: Fitness for Your Immune System, Aviva Romm, MD
https://avivaromm.com/medicinal-mushrooms-immune-system/

758. Manash Pratim Pathak, Kalyani Pathak, Riya Saikia, Urvashee Gogoi, Mohammad Zaki Ahmad, Pompy Patowary, Aparoop Das, Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review, Biomedicine & Pharmacotherapy, Volume 149, 2022, 112901, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2022.112901.
https://www.sciencedirect.com/science/article/pii/S0753332222002906

759. Vlasenko, Vyacheslav & Vlasenko, Anastasia & Turmunkh, Dejidmaa & Dondov, Budsuren. (2021). First Data on Antiviral Activity of Aqueous Extracts from Medicinal Mushrooms from the Altai Mountains in Russia against Influenza Virus Type A. International Journal of Medicinal Mushrooms. 23. 37-45.
https://www.researchgate.net/publication/356811510_First_Data_on_Antiviral_Activity_of_Aqueous_Extracts_from_Medicinal_Mushrooms_from_the_Altai_Mountains_in_Russia_against_Influenza_Virus_Type_A

760. Arunachalam K, Sasidharan SP, Yang X. A concise review of mushrooms antiviral and immunomodulatory properties that may combat against COVID-19. Food Chem Adv. 2022 Oct;1:100023. doi: 10.1016/j.focha.2022.100023. Epub 2022 Mar 2. PMID: 36686330; PMCID: PMC8887958.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8887958/

761. Seo DJ, Choi C. Antiviral Bioactive Compounds of Mushrooms and Their Antiviral Mechanisms: A Review. Viruses. 2021 Feb 23;13(2):350. doi: 10.3390/v13020350. PMID: 33672228; PMCID: PMC7926341.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7926341/

762. News New discovery could help protect against influenza, McGill University, 18/2/25
https://www.mcgill.ca/newsroom/channels/news/new-discovery-could-help-protect-against-influenza-363625

763. Hetland G, Johnson E, Bernardshaw SV, Grinde B. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation?. Scand J Immunol. 2021; 93:e12937. https://doi.org/10.1111/sji.12937
https://onlinelibrary.wiley.com/doi/10.1111/sji.12937

1. Flu (Influenza), national foundation for infectious diseases, 2023
https://www.nfid.org/infectious-disease/flu/

2. Dobson R. Flu costs the US $90bn a year, report shows. BMJ. 2007 Jun 2;334(7604):1134. doi: 10.1136/bmj.39226.597951.DB. PMCID: PMC1885332.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885332/

3. de Courville C, Cadarette SM, Wissinger E, Alvarez FP. The economic burden of influenza among adults aged 18 to 64: A systematic literature review. Influenza Other Respir Viruses. 2022 May;16(3):376-385. doi: 10.1111/irv.12963. Epub 2022 Feb 5. PMID: 35122389; PMCID: PMC8983919.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8983919/

4. Meltzer MI, Cox NJ, Fukuda K. The economic impact of pandemic influenza in the United States: priorities for intervention. Emerg Infect Dis. 1999 Sep-Oct;5(5):659-71. doi: 10.3201/eid0505.990507. PMID: 10511522; PMCID: PMC2627723.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2627723/

5. Schoenbaum SC. Economic impact of influenza. The individual's perspective. Am J Med. 1987 Jun 19;82(6A):26-30. doi: 10.1016/0002-9343(87)90557-2. PMID: 3109239.
https://www.amjmed.com/article/0002-9343(87)90557-2/fulltext

6. Prager F, Wei D, Rose A. Total Economic Consequences of an Influenza Outbreak in the United States. Risk Anal. 2017 Jan;37(1):4-19. doi: 10.1111/risa.12625. Epub 2016 May 23. PMID: 27214756.
https://onlinelibrary.wiley.com/doi/abs/10.1111/risa.12625

Α1. Zhu, Qinchang & Amen, Yhiya & Ohnuki, Koichiro & Shimizu, Kuniyoshi. (2017). Anti-influenza effects of Ganoderma lingzhi : An animal study. Journal of Functional Foods. 34. 224-228. 10.1016/j.jff.2017.04.040.
https://www.sciencedirect.com/science/article/abs/pii/S1756464617302232

Α2. Oke MA, Afolabi FJ, Oyeleke OO, Kilani TA, Adeosun AR, Olanbiwoninu AA and Adebayo EA (2022) Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa. Front. Pharmacol. 13:952027. doi: 10.3389/fphar.2022.952027
https://www.frontiersin.org/articles/10.3389/fphar.2022.952027/full

Α3. Dai WF, Guo PX, Tu ZC, Li RT, Cheng YX. Five new compounds from the fungus Ganoderma petchii. Fitoterapia. 2015 Oct;106:68-71. doi: 10.1016/j.fitote.2015.08.002. Epub 2015 Aug 12. PMID: 26277755.
https://pubmed.ncbi.nlm.nih.gov/26277755/

Α4. Eo SK, Kim YS, Lee CK, Han SS. Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum. J Ethnopharmacol. 1999 Dec 15;68(1-3):129-36. doi: 10.1016/s0378-8741(99)00067-7. PMID: 10624872.
https://pubmed.ncbi.nlm.nih.gov/10624872/

Α5. Mothana RA, Awadh Ali NA, Jansen R, Wegner U, Mentel R, Lindequist U. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia. 2003 Feb;74(1-2):177-80. doi: 10.1016/s0367-326x(02)00305-2. PMID: 12628419.
https://pubmed.ncbi.nlm.nih.gov/12628419/

Α6. Avtonomova AV, Krasnopolskaya LM. [Antiviral properties of basidiomycetes metabolites]. Antibiot Khimioter. 2014;59(7-8):41-8. Russian. PMID: 25975107.
https://pubmed.ncbi.nlm.nih.gov/25975107/

Α7. Zhu Q, Bang TH, Ohnuki K, Sawai T, Sawai K, Shimizu K. Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design. Sci Rep. 2015 Aug 26;5:13194. doi: 10.1038/srep13194. PMID: 26307417; PMCID: PMC4549708.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549708/

Α8. Çelik B, Özparlak H. Determination of genotoxic and antigenotoxic effects of wild-grown Reishi mushroom (Ganoderma lucidum) using the hen's egg test for analysis of micronucleus induction. Biotech Histochem. 2019 Nov;94(8):628-636. doi: 10.1080/10520295.2019.1622784. Epub 2019 Jul 8. PMID: 31282205.
https://pubmed.ncbi.nlm.nih.gov/31282205/

Α9.  "Fuzheng Quxie" and antiviral effect of Ganoderma (Lingzhi) Lin, ZhiBin. Chinese Journal of Pharmacology and Toxicology ; 34(6):401-407, 2020. Artigo em Chinês | CAB Abstracts | ID: covidwho-1863984
https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/pt/covidwho-1863984

Α10. Vlassopoulou M, Yannakoulia M, Pletsa V, Zervakis GI, Kyriacou A. Effects of fungal beta-glucans on health - a systematic review of randomized controlled trials. Food Funct. 2021 Apr 26;12(8):3366-3380. doi: 10.1039/d1fo00122a. PMID: 33876798.
https://pubmed.ncbi.nlm.nih.gov/33876798/

Α11. Zhang C, Zhang G, Zhang Y, Lin X, Zhao X, Cui Q, Rong L, Du R. Development of an HiBiT-tagged reporter H3N2 influenza A virus and its utility as an antiviral screening platform. J Med Virol. 2023 Jan;95(1):e28345. doi: 10.1002/jmv.28345. PMID: 36424458.
https://pubmed.ncbi.nlm.nih.gov/36424458/

Α12. Gracián-Alcaide, Carlos & Maldonado-Lobón, José & Ortiz-Tikkakoski, Elisabeth & Gómez-Vilchez, Alejandro & López-Larramendi, Jose & Olivares, Mónica & Blanco-Rojo, Ruth. (2020). Effects of a Combination of Elderberry and Reishi Extracts on the Duration and Severity of Respiratory Tract Infections in Elderly Subjects: A Randomized Controlled Trial. Applied Sciences. 10. 8559. 10.3390/app10228259.
https://www.researchgate.net/publication/346192717_Effects_of_a_Combination_of_Elderberry_and_Reishi_Extracts_on_the_Duration_and_Severity_of_Respiratory_Tract_Infections_in_Elderly_Subjects_A_Randomized_Controlled_Trial

Α13. Henao SLD, Urrego SA, Cano AM, Higuita EA. Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with β-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. Int J Med Mushrooms. 2018;20(8):705-716. doi: 10.1615/IntJMedMushrooms.2018026986. PMID: 30317947.
https://pubmed.ncbi.nlm.nih.gov/30317947/



Μακροχρόνιου (long) COVID
476. What is Long COVID and how is it treated, 9 May 2025, National Centre for Infectious Diseases
https://www.ncid.sg/News-Events/News/Pages/What-is-Long-COVID-and-how-is-it-treated.aspx

477. Alwan NA, Johnson L. Defining long COVID: Going back to the start. Med. 2021 May 14;2(5):501-504. doi: 10.1016/j.medj.2021.03.003. Epub 2021 Mar 25. PMID: 33786465; PMCID: PMC7992371.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7992371/

478. Al-Oraibi A, Woolf K, Naidu J, Nellums LB, Pan D, Sze S, Tarrant C, Martin CA, Gogoi M, Nazareth J, Divall P, Dempsey B, Lamb D, Pareek M. Global prevalence of long COVID and its most common symptoms among healthcare workers: a systematic review and meta-analysis. BMJ Public Health. 2025 Apr 17;3(1):e000269. doi: 10.1136/bmjph-2023-000269. PMID: 40260126; PMCID: PMC12010341.
https://pmc.ncbi.nlm.nih.gov/articles/PMC12010341/

479. Global Prevalence of Long COVID, its Subtypes and Risk factors: An Updated Systematic Review and Meta-Analysis Yiren Hou, Tian Gu, Zhouchi Ni, Xu Shi, Megan L. Ranney, Bhramar Mukherjee medRxiv 2025.01.01.24319384; doi: https://doi.org/10.1101/2025.01.01.24319384
https://www.medrxiv.org/content/10.1101/2025.01.01.24319384v1.full

480. Lucas Etienne Hermans, Sean Wasserman, Lizhen Xu, John Eikelboom - Long COVID prevalence and risk factors in adults residing in middle- and high-income countries: secondary analysis of the multinational Anti-Coronavirus Therapies (ACT) trials: BMJ Global Health 2025;10:e017126.
https://gh.bmj.com/content/10/4/e017126

481. Hastie, C.E., Lowe, D.J., McAuley, A. et al. True prevalence of long-COVID in a nationwide, population cohort study. Nat Commun 14, 7892 (2023). https://doi.org/10.1038/s41467-023-43661-w
https://www.nature.com/articles/s41467-023-43661-w

482. Trofor AC, Robu Popa D, Melinte OE, Trofor L, Vicol C, Grosu-Creangă IA, Crișan Dabija RA, Cernomaz AT. Looking at the Data on Smoking and Post-COVID-19 Syndrome-A Literature Review. J Pers Med. 2024 Jan 16;14(1):97. doi: 10.3390/jpm14010097. PMID: 38248798; PMCID: PMC10821354.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10821354/

483. de Granda-Orive JI, Solano-Reina S, Jiménez-Ruiz CA. Are Smoking and Vaping Risk Factors of Developing Long and Persistent Post-COVID-19? Open Respir Arch. 2022 Jul 29;4(4):100195. doi: 10.1016/j.opresp.2022.100195. PMID: 37496961; PMCID: PMC9335855.
https://www.elsevier.es/en-revista-open-respiratory-archives-11-avance-resumen-are-smoking-vaping-risk-factors-S2659663622000418

484.  Long-term effects of COVID-19 (long COVID), NHS UK, 21 March 2023
https://www.nhs.uk/conditions/covid-19/long-term-effects-of-covid-19-long-covid/

485. Seo JW, Kim SE, Kim Y, Kim EJ, Kim T, Kim T, Lee SH, Lee E, Lee J, Seo YB, Jeong YH, Jung YH, Choi YJ, Song JY. Updated Clinical Practice Guidelines for the Diagnosis and Management of Long COVID. Infect Chemother. 2024 Mar;56(1):122-157. doi: 10.3947/ic.2024.0024. Epub 2024 Mar 13. PMID: 38527781; PMCID: PMC10990882.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10990882/

486. Long Covid and diet, British Dietetic Association
https://www.bda.uk.com/resource/long-covid-and-diet.html

487. Guerra G, Lucariello A, Komici K. Editorial: Long COVID: nutrition and lifestyle changes. Front Nutr. 2024 Feb 21;11:1375449. doi: 10.3389/fnut.2024.1375449. PMID: 38450231; PMCID: PMC10915234.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10915234/

488. Booi, Han-Ni & Lee, mei k & Fung, Shin & Ng, Szuting & Tan, Chon-Seng & Lim, Kuan-Hon & Roberts, Richard & Ting, Kang. (2022). Medicinal Mushrooms and Their Use to Strengthen Respiratory Health During and Post-COVID-19 Pandemic. International Journal of Medicinal Mushrooms. 24. 10.1615/IntJMedMushrooms.2022045068.
https://www.researchgate.net/publication/362027865_Medicinal_Mushrooms_and_Their_Use_to_Strengthen_Respiratory_Health_During_and_Post-COVID-19_Pandemic

489. Slomski A. Trials Test Mushrooms and Herbs as Anti–COVID-19 Agents. JAMA. 2021;326(20):1997–1999. doi:10.1001/jama.2021.19388
https://jamanetwork.com/journals/jama/fullarticle/2786023

490. Phillips JM, Ooi SL, Pak SC. Health-Promoting Properties of Medicinal Mushrooms and Their Bioactive Compounds for the COVID-19 Era-An Appraisal: Do the Pro-Health Claims Measure Up? Molecules. 2022 Apr 1;27(7):2302. doi: 10.3390/molecules27072302. PMID: 35408701; PMCID: PMC9000601.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9000601/

491. Karuppusamy Arunachalam, Sreeja Puthanpura Sasidharan, Xuefei Yang, A concise review of mushrooms antiviral and immunomodulatory properties that may combat against COVID-19, Food Chemistry Advances, Volume 1, 2022, 100023, ISSN 2772-753X, https://doi.org/10.1016/j.focha.2022.100023.
https://www.sciencedirect.com/science/article/pii/S2772753X22000120

492. Hetland G, Johnson E, Bernardshaw SV, Grinde B. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation? Scand J Immunol. 2021 Jan;93(1):e12937. doi: 10.1111/sji.12937. Epub 2020 Jul 29. PMID: 32657436; PMCID: PMC7404338.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7404338/

493. Chapter Medicinal Mushrooms as Nutritional Management for Post COVID-19 Syndromes ByNehal M. El-Deeb, Hesham Ali El Enshasy, Aya M. Fouad, Ahmed M. Kenawy Book Bioprospects of Macrofungi Edition 1st Edition First Published 2023
https://www.taylorfrancis.com/chapters/edit/10.1201/9781003343806-17/medicinal-mushrooms-nutritional-management-post-covid-19-syndromes-nehal-el-deeb-hesham-ali-el-enshasy-aya-fouad-ahmed-kenawy



Παιδική επιληψία
1. Kim-McManus O, Boylan S, Nespeca M. Serendipity Can Rule the Day: Remarkable Efficacy of a Mushroom Extract Powder in Childhood Treatment-Resistant Epilepsy. Pediatr Neurol. 2025 Apr;165:56-59. doi: 10.1016/j.pediatrneurol.2025.01.017. Epub 2025 Jan 24. PMID: 39951934.
https://pubmed.ncbi.nlm.nih.gov/39951934/

2. Medicine (Baltimore). 2018 Jun;97(23):e10941. A retrospective study of Ganoderma Lucidum Spore Powder for patients with epilepsy. Wang GH1, Li X1, Cao WH2, Li J3, Wang LH1.



Χρόνια ηπατίτιδα Β
653. Staging liver fibrosis and cirrhosis using non-invasive tests in people with chronic hepatitis B to inform WHO 2024 guidelines: a systematic review and meta-analysis     Liguori, Antonio et al.     The Lancet Gastroenterology & Hepatology, Volume 10, Issue 4, 332 - 349
https://www.thelancet.com/journals/langas/article/PIIS2468-1253(24)00437-0/fulltext

654. Ji Huang, Yongqi Liu, Youshun Liu, Antiviral therapy in hepatitis B virus-infected with immune-tolerant: A meta-analysis, Gastroenterología y Hepatología (English Edition), Volume 46, Issue 4, 2023, Pages 309-318, ISSN 2444-3824, https://doi.org/10.1016/j.gastre.2022.05.011.
https://www.sciencedirect.com/science/article/abs/pii/S2444382423000706

655. Parikh P, Ryan JD, Tsochatzis EA. Fibrosis assessment in patients with chronic hepatitis B virus (HBV) infection. Ann Transl Med. 2017 Feb;5(3):40. doi: 10.21037/atm.2017.01.28. PMID: 28251119; PMCID: PMC5326648.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5326648/

656. You, H., Wang, X., Ma, L. et al. Insights into the impact of hepatitis B virus on hepatic stellate cell activation. Cell Commun Signal 21, 70 (2023). https://doi.org/10.1186/s12964-023-01091-7
https://biosignaling.biomedcentral.com/articles/10.1186/s12964-023-01091-7

657. Bedossa P. Reversibility of hepatitis B virus cirrhosis after therapy: who and why? Liver Int. 2015 Jan;35 Suppl 1:78-81. doi: 10.1111/liv.12710. PMID: 25529091.
https://pubmed.ncbi.nlm.nih.gov/25529091/

658. Yameng Sun, Xiaoning Wu, Jialing Zhou, Tongtong Meng, Bingqiong Wang, Shuyan Chen, Hui Liu, Tailing Wang, Xinyan Zhao, Shanshan Wu, Yuanyuan Kong, Xiaojuan Ou, Aileen Wee, Neil D. Theise, Chao Qiu, Wenhong Zhang, Fengmin Lu, Jidong Jia, Hong You, Persistent Low Level of Hepatitis B Virus Promotes Fibrosis Progression During Therapy, Clinical Gastroenterology and Hepatology, Volume 18, Issue 11, 2020, Pages 2582-2591.e6, ISSN 1542-3565, https://doi.org/10.1016/j.cgh.2020.03.001.
https://www.sciencedirect.com/science/article/pii/S154235652030272X

659. Soares AA, de Sá-Nakanishi AB, Bracht A, da Costa SM, Koehnlein EA, de Souza CG, Peralta RM. Hepatoprotective effects of mushrooms. Molecules. 2013 Jul 1;18(7):7609-30. doi: 10.3390/molecules18077609. PMID: 23884116; PMCID: PMC6270077.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6270077/

660. Bhatia, Aditya & Neeraj, Dr. (2024). Medicinal Mushrooms: A promising frontier in hepatitis treatment. 05. 19-24.
https://www.researchgate.net/publication/380721790_Medicinal_Mushrooms_A_promising_frontier_in_hepatitis_treatment

661. Hsu CH, Hwang KC, Chiang YH, Chou P. The mushroom Agaricus blazei Murill extract normalizes liver function in patients with chronic hepatitis B. J Altern Complement Med. 2008 Apr;14(3):299-301. doi: 10.1089/acm.2006.6344. PMID: 18370584.
https://pubmed.ncbi.nlm.nih.gov/18370584

662. Gao, Yihuai & Zhou, Shufeng & Chen, Guoliang & Dai, Xihu & Ye, Jingxian & Gao, He. (2002). A Phase I/II Study of a Ganoderma lucidum (Curt.: Fr.) P. Karst. (Ling Zhi, Reishi Mushroom) Extract in Patients with Chronic Hepatitis ?. International Journal of Medicinal Mushrooms. 4. 7. 10.1615/IntJMedMushr.v4.i4.50.
https://www.researchgate.net/publication/269620103_A_Phase_III_Study_of_a_Ganoderma_lucidum_Curt_Fr_P_Karst_Ling_Zhi_Reishi_Mushroom_Extract_in_Patients_with_Chronic_Hepatitis

663. Zhou L, Yang W, Xu Y, Zhu Q, Ma Z, Zhu T, Ge X, Gao J. [Short-term curative effect of cultured Cordyceps sinensis (Berk.) Sacc. Mycelia in chronic hepatitis B]. Zhongguo Zhong Yao Za Zhi. 1990 Jan;15(1):53-5, 65. Chinese. PMID: 1693509.
https://pubmed.ncbi.nlm.nih.gov/1693509/

664. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med. 1998 Winter;4(4):429-57. doi: 10.1089/acm.1998.4.429. PMID: 9884180.
https://pubmed.ncbi.nlm.nih.gov/9884180/

665. Gong HY, Wang KQ, Tang SG. [Effects of cordyceps sinensis on T lymphocyte subsets and hepatofibrosis in patients with chronic hepatitis B]. Hunan Yi Ke Da Xue Xue Bao. 2000 Jun 28;25(3):248-50. Chinese. PMID: 12212155.
https://pubmed.ncbi.nlm.nih.gov/12212155/

666.Simonić, Jasmina & Stajic, Mirjana & Vukojevic, Jelena. (2017). Ganoderma lucidum - from tradition to modern medicine. Zbornik Matice srpske za prirodne nauke. 151-161. 10.2298/ZMSPN1733151C.
https://www.researchgate.net/publication/322460312_Ganoderma_lucidum_-_from_tradition_to_modern_medicine



HPV
307. WHO, Cervical cancer 5 March 2024,
https://www.who.int/news-room/fact-sheets/detail/cervical-cancer

308. Jie Wu, Qianyun Jin, Yunmeng Zhang, Yuting Ji, Jingjing Li, Xiaomin Liu, Hongyuan Duan, Zhuowei Feng, Ya Liu, Yacong Zhang, Zhangyan Lyu, Lei Yang, Yubei Huang, Global burden of cervical cancer: current estimates, temporal trend and future projections based on the GLOBOCAN 2022, Journal of the National Cancer Center, 2025, , ISSN 2667-0054, https://doi.org/10.1016/j.jncc.2024.11.006.
https://www.sciencedirect.com/science/article/pii/S2667005425000134

309. Cervical Cancer Leads Cancer Deaths  for Women in 37 Countries,  July 29, 2024 Sandy McDowell | Managing Editor Research Written by: Sandy McDowell Editorial Director, Digital Research Content, American Cancer Society
https://www.cancer.org/research/acs-research-news/cervical-cancer-leads-cancer-deaths-37-countries.html

310. Okunade KS. Human papillomavirus and cervical cancer. J Obstet Gynaecol. 2020 Jul;40(5):602-608. doi: 10.1080/01443615.2019.1634030. Epub 2019 Sep 10. Erratum in: J Obstet Gynaecol. 2020 May;40(4):590. doi: 10.1080/01443615.2020.1713592. PMID: 31500479; PMCID: PMC7062568.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7062568/

311. Medicinal Mushrooms (PDQ®)–Health Professional Version, National Cancer Institute
https://www.cancer.gov/about-cancer/treatment/cam/hp/mushrooms-pdq

312. Donatini B. Control of oral human papillomavirus (HPV) by medicinal mushrooms, Trametes versicolor and Ganoderma lucidum: a preliminary clinical trial. Int J Med Mushrooms. 2014;16(5):497-8. doi: 10.1615/intjmedmushrooms.v16.i5.80. PMID: 25271984.
https://pubmed.ncbi.nlm.nih.gov/25271984/



Καλλυντικές Ιδιότητες
1. Badalyan SM, Barkhudaryan A, Rapior S. Medicinal Macrofungi as Cosmeceuticals: A Review. Int J Med Mushrooms. 2022;24(4):1-13. doi: 10.1615/IntJMedMushrooms.2022043124. PMID: 35695592.
https://www.researchgate.net/publication/359788208_Medicinal_Macrofungi_as_Cosmeceuticals_A_Review



Καρδιοπάθειες
370. Nouruzi S, Vasheghani Farahani A, Rezaeizadeh H, Ghafouri P, Ghorashi SM, Omidi N. Platelet Aggregation Inhibition: An Evidence-Based Systematic Review on the Role of Herbs for Primary Prevention Based on Randomized Controlled Trials. Iran J Med Sci. 2022 Nov;47(6):505-516. doi: 10.30476/IJMS.2021.91328.2247. PMID: 36380973; PMCID: PMC9652499.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9652499/

371. Wascher TC, Saely CH; den Ausschuss Leitlinien. Thrombozytenaggregationshemmer (Update 2019) [Inhibition of platelet aggregation (Update 2019)]. Wien Klin Wochenschr. 2019 May;131(Suppl 1):139-140. German. doi: 10.1007/s00508-018-1437-6. PMID: 30980156.
https://pubmed.ncbi.nlm.nih.gov/30980156/

372. Roy, S., Paul, K. Nourishing the clot: a comprehensive review of dietary habits and their implications for platelet function. Bull Fac Phys Ther 29, 7 (2024). https://doi.org/10.1186/s43161-023-00173-4
https://bfpt.springeropen.com/articles/10.1186/s43161-023-00173-4

373. Duttaroy, A.K. Functional Foods in Preventing Human Blood Platelet Hyperactivity-Mediated Diseases—An Updated Review. Nutrients 2024, 16, 3717. https://doi.org/10.3390/nu16213717
https://www.mdpi.com/2072-6643/16/21/3717

374.  Yoshimoto, H.; Miyazawa, N.; Eguchi, F. Wild and Cultivated Mushrooms Exhibit Anti-Inflammatory Effects Including Inhibition of Platelet Aggregation and Interleukin-8 Expression. Appl. Microbiol. 2025, 5, 36. https://doi.org/10.3390/applmicrobiol5020036
https://www.mdpi.com/2673-8007/5/2/36


278. Németh, Z.; Paulinné Bukovics, M.; Sümegi, L.D.; Sturm, G.; Takács, I.; Simon-Szabó, L. The Importance of Edible Medicinal Mushrooms and Their Potential Use as Therapeutic Agents Against Insulin Resistance. Int. J. Mol. Sci. 2025, 26, 827. https://doi.org/10.3390/ijms26020827
https://www.mdpi.com/1422-0067/26/2/827

279. Kiho T, Yamane A, Hui J, Usui S, Ukai S. Polysaccharides in fungi. XXXVI. Hypoglycemic activity of a polysaccharide (CS-F30) from the cultural mycelium of Cordyceps sinensis and its effect on glucose metabolism in mouse liver. Biol Pharm Bull. 1996 Feb;19(2):294-6. doi: 10.1248/bpb.19.294. PMID: 8850325.
https://www.jstage.jst.go.jp/article/bpb1993/19/2/19_2_294/_article

280. Hypolipidemic effect of exo- and endo-biopolymers produced from submerged mycelial culture of Ganoderma lucidum in rats  By: Yang, Byung-Keun Journal of Microbiology and Biotechnology (2002), 12(6), 872-877 CODEN: JOMBES; ISSN: 1017-7825
https://chemport-n.cas.org//chemport-n/?APP=ftslink&action=reflink&origin=npg&version=1.0&coi=1%3ACAS%3A528%3ADC%2BD3sXhvVyrs7s%3D&md5=81df50e26d135d0e7d203517b6259c6e

281. L. Liang, Z. Zhang, W. Sun and Y. Wang, "Effect of the Inonotus Obliquus Polysaccharides on Blood Lipid Metabolism and Oxidative Stress of Rats Fed High-Fat Diet In Vivo," 2009 2nd International Conference on Biomedical Engineering and Informatics, Tianjin, China, 2009, pp. 1-4, doi: 10.1109/BMEI.2009.5305591.
https://ieeexplore.ieee.org/document/5305591

282. Kim, SY., Chung, SI., Nam, SH. et al. Cholesterol lowering action and antioxidant status improving efficacy of noodles made from unmarketable oak mushroom (Lentinus edodes) in high cholesterol fed rats. J. Korean Soc. Appl. Biol. Chem. 52, 207–212 (2009). https://doi.org/10.3839/jksabc.2009.038
https://applbiolchem.springeropen.com/articles/10.3839/jksabc.2009.038#citeas

283. Hiwatashi K, Kosaka Y, Suzuki N, Hata K, Mukaiyama T, Sakamoto K, Shirakawa H, Komai M. Yamabushitake mushroom (Hericium erinaceus) improved lipid metabolism in mice fed a high-fat diet. Biosci Biotechnol Biochem. 2010;74(7):1447-51. doi: 10.1271/bbb.100130. Epub 2010 Jul 7. PMID: 20622452.
https://pubmed.ncbi.nlm.nih.gov/20622452/

284. Handayani, Dian & Chen, J & Meyer, B & Huang, Xu-Feng. (2011). Dietary Shiitake Mushroom (Lentinus edodes) Prevents Fat Deposition and Lowers Triglyceride in Rats Fed a High-Fat Diet. Journal of obesity. 2011. 258051. 10.1155/2011/258051.
https://www.researchgate.net/publication/51746881_Dietary_Shiitake_Mushroom_Lentinus_edodes_Prevents_Fat_Deposition_and_Lowers_Triglyceride_in_Rats_Fed_a_High-Fat_Diet

285. Choi WS, Kim YS, Park BS, Kim JE, Lee SE. Hypolipidaemic Effect of Hericium erinaceum Grown in Artemisia capillaris on Obese Rats. Mycobiology. 2013 Jun;41(2):94-9. doi: 10.5941/MYCO.2013.41.2.94. Epub 2013 Jun 30. PMID: 23874132; PMCID: PMC3714447.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3714447/

286. Henriques, Gilberto & Helm, Cristiane & Busato, Ana & Simeone, Maria. (2016). Lipid profile and glycemic response of rats fed on a semi-purified diet supplemented with Agaricus brasiliensis mushroom. Acta Scientiarum. Health Sciences. 38. 71. 10.4025/actascihealthsci.v38i1.29185.
https://www.redalyc.org/journal/3072/307245984010/html/

287. Anwar H, Suchodolski JS, Ullah MI, Hussain G, Shabbir MZ, Mustafa I, Sohail MU. Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes), Supplementation Alters Gut Microbiome and Corrects Dyslipidemia in Rats. Int J Med Mushrooms. 2019;21(1):79-88. doi: 10.1615/IntJMedMushrooms.2018029348.
https://qspace.qu.edu.qa/handle/10576/11369?show=full

288. Olaide Olawunmi Ajibola, Cirilo Nolasco-Hipolito, Octavio Carvajal-Zarrabal, Shanti F Salleh, Gbadebo C Adeyinka, Stephen A Adefegha, Mirja K Ahmmed, Kazi Sumaiya, Raymond Thomas, Turkey tail mushroom (Trametes versicolor): an edible macrofungi with immense medicinal properties, Current Opinion in Food Science, Volume 58, 2024, 101191, ISSN 2214-7993, https://doi.org/10.1016/j.cofs.2024.101191.
https://www.sciencedirect.com/science/article/pii/S2214799324000699

289. African Journal of Biotechnology Vol. 5 (13), pp. 1263-1266, 3 July 2006 Available online at http://www.academicjournals.org/AJB ISSN 1684–5315 © 2006 Academic Journals. Responses of plasma lipids to edible mushroom diets in albino rats Oyetayo, F.L Department of Biochemistry, University of Ado-Ekiti, Nigeria. E-mail: [email protected].
https://www.ajol.info/index.php/ajb/article/view/43095

290. alzdiscovery.org. Lion's mane, 8/9/2026
https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Lions-Mane-Cognitive-Vitality-For-Researchers.pdf

291. Samarasinghe, M W A Kanchana Priyadarshani & Waisundara, Viduranga. (2020). Therapeutic Properties and Anti-Lipidemic Activity of Cordyceps sinensis. 10.5772/intechopen.92616.
https://www.intechopen.com/chapters/72232

292. Phillips, J.M.; Ooi, S.L.; Pak, S.C. Health-Promoting Properties of Medicinal Mushrooms and Their Bioactive Compounds for the COVID-19 Era—An Appraisal: Do the Pro-Health Claims Measure Up? Molecules 2022, 27, 2302. https://doi.org/10.3390/ molecules27072302
https://researchoutput.csu.edu.au/ws/portalfiles/portal/347095015/213340870_Published_article.pdf

293. Bhambri A, Srivastava M, Mahale VG, Mahale S and Karn SK (2022) Mushrooms as Potential Sources of Active Metabolites and Medicines. Front. Microbiol. 13:837266. doi: 10.3389/fmicb.2022.837266
https://www.frontiersin.org/journals/microbiology/articles/10.3389/fmicb.2022.837266/full

294. Consuming Mushrooms When Adopting a Healthy Mediterranean-Style Dietary Pattern Does Not Influence Short-Term Changes of Most Cardiometabolic Disease Risk Factors in Healthy Middle-Aged and Older Adults Uffelman, Cassi N et al. The Journal of Nutrition, Volume 154, Issue 2, 574 - 582
https://jn.nutrition.org/article/S0022-3166(23)72815-0/fulltext

364. Iqbal AM, Jamal SF. Essential Hypertension. [Updated 2023 Jul 20]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK539859/

365. Essential hypertension, 08 Jan 2025, BMJ Best Practice
https://bestpractice.bmj.com/topics/en-gb/26

366. Chen S. Essential hypertension: perspectives and future directions. J Hypertens. 2012 Jan;30(1):42-5. doi: 10.1097/HJH.0b013e32834ee23c. PMID: 22157586; PMCID: PMC4152852.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4152852/

367. Carthy ER. Autonomic dysfunction in essential hypertension: A systematic review. Ann Med Surg (Lond). 2013 Dec 11;3(1):2-7. doi: 10.1016/j.amsu.2013.11.002. PMID: 25568776; PMCID: PMC4268473.
https://www.sciencedirect.com/science/article/pii/S2049080113000034

368. Verdecchia P, Schillaci G, Borgioni C, Ciucci A, Zampi I, Battistelli M, Gattobigio R, Sacchi N, Porcellati C. Cigarette smoking, ambulatory blood pressure and cardiac hypertrophy in essential hypertension. J Hypertens. 1995 Oct;13(10):1209-15. doi: 10.1097/00004872-199510000-00016. PMID: 8586813.
https://pubmed.ncbi.nlm.nih.gov/8586813/

369. Mohamad Ansor, N., Abdullah, N. & Aminudin, N. Anti-angiotensin converting enzyme (ACE) proteins from mycelia of Ganoderma lucidum (Curtis) P. Karst. BMC Complement Altern Med 13, 256 (2013). https://doi.org/10.1186/1472-6882-13-256
https://link.springer.com/article/10.1186/1472-6882-13-256



Νόσος Κρον
343. Ranasinghe IR, Tian C, Hsu R. Crohn Disease. [Updated 2024 Feb 24]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK436021/

344. Lin, D., Jin, Y., Shao, X. et al. Global, regional, and national burden of inflammatory bowel disease, 1990–2021: Insights from the global burden of disease 2021. Int J Colorectal Dis 39, 139 (2024).https://doi.org/10.1007/s00384-024-04711-x
https://link.springer.com/article/10.1007/s00384-024-04711-x

345. Five Types of Crohn's Disease | North Shore Gastroenterology
https://www.northshoregastro.org/2020/10/16/five-types-of-crohns-disease/

346. Molodecky NA, Kaplan GG. Environmental risk factors for inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2010 May;6(5):339-46. PMID: 20567592; PMCID: PMC2886488.
https://pmc.ncbi.nlm.nih.gov/articles/PMC2886488/

347. Berkowitz L, Schultz BM, Salazar GA, Pardo-Roa C, Sebastián VP, Álvarez-Lobos MM and Bueno SM (2018) Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis. Front. Immunol. 9:74. doi: 10.3389/fimmu.2018.00074
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2018.00074/full

348. What is Crohn's disease? A Mayo Clinic expert explains  Learn more about Crohn's disease from gastroenterologist William Faubion, M.D.,  Oct. 29, 2024
https://www.mayoclinic.org/diseases-conditions/crohns-disease/symptoms-causes/syc-20353304

349. Last Reviewed July 2024, Diagnosis of Crohn’s Disease, the National Institute of Diabetes and Digestive and Kidney Diseases
https://www.niddk.nih.gov/health-information/digestive-diseases/crohns-disease/diagnosis

350. Bischoff SC, Escher J, Hébuterne X, Kłęk S, Krznaric Z, Schneider S, Shamir R, Stardelova K, Wierdsma N, Wiskin AE, Forbes A. ESPEN practical guideline: Clinical Nutrition in inflammatory bowel disease. Clin Nutr. 2020 Mar;39(3):632-653. doi: 10.1016/j.clnu.2019.11.002. Epub 2020 Jan 13. PMID: 32029281.
https://www.espen.org/files/ESPEN-Guidelines/ESPEN_practical_guideline_Clinical_Nutrition_in_inflammatory_bowel_disease.pdf

351.  October 3, 2014 19 Μαίου Παγκόσμια Ημέρα ΙΦΝΕ  Σύλλογος Ατόμων με Νόσο του Crohn και Ελκώδη Κολίτιδα Ελλάδας (HELLESCC)
https://crohnhellas.gr/19-maiou-pagkosmia-imera-ifne-2012/

352. Liu C, Dunkin D, Lai J, et al. Anti-inflammatory Effects of Ganoderma lucidum Triterpenoid in Human Crohn's Disease Associated with Downregulation of NF-κB Signaling. Inflammatory Bowel Diseases. 2015 Aug;21(8):1918-1925. DOI: 10.1097/mib.0000000000000439. PMID: 25993687; PMCID: PMC4509964.
https://europepmc.org/article/MED/25993687

353. Vlassopoulou M, Yannakoulia M, Pletsa V, Zervakis GI, Kyriacou A. Effects of fungal beta-glucans on health - a systematic review of randomized controlled trials. Food Funct. 2021 Apr 26;12(8):3366-3380. doi: 10.1039/d1fo00122a. PMID: 33876798.
https://pubmed.ncbi.nlm.nih.gov/33876798/

354. Randomized Clinical Trial for the Evaluation of Immune Modulation by Yogurt Enriched with β-Glucans from Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), in Children from Medellin, Colombia. Henao SLD, Urrego SA, Cano AM, Higuita EA. Int J Med Mushrooms. 2018;20(8):705-716.
https://pubmed.ncbi.nlm.nih.gov/30317947/

355. Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E. Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study. PLoS One. 2016 Jul 14;11(7):e0159288. doi: 10.1371/journal.pone.0159288. PMID: 27415795; PMCID: PMC4944955.
https://europepmc.org/article/MED/27415795

356. Cytokine Levels After Consumption of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, in Patients with Crohn's Disease and Ulcerative Colitis in a Randomized Single-Blinded Placebo-Controlled Study S. P. Therkelsen,  G. Hetland,  T. Lyberg,  I. Lygren,  E. Johnson
https://onlinelibrary.wiley.com/doi/10.1111/sji.12476



Μελατονίνη
258. Wei Chen, Jun-Wen Yu, Yu-Yi Deng, Lut Yi Wong, Chen Wang, Yu-Ling Liang, Yuk-Tung Leung, Jia-Yi Tian, Ying Wu, Kelvin Sze-Yin Leung, Jinhui Hu, Wen-Hua Chen, Xiaobing Dou, Xiu-Qiong Fu, Ying-Jie Chen, Zhi-Ling Yu, Identification of sedative-hypnotic compounds shared by five medicinal Polyporales mushrooms using UPLC-Q-TOF-MS/MS-based untargeted metabolomics, Phytomedicine, Volume 128, 2024, 155355, ISSN 0944-7113, https://doi.org/10.1016/j.phymed.2024.155355.
https://www.sciencedirect.com/science/article/abs/pii/S0944711324000205

259. Tselepis, George & Palamiotis, Ioannis & Georgiou, Sofia. (2023). Homeostasis of Circadian Rhythm and Therapeutic Approaches to Manage its Related-Disorders: The Case of Medicinal Mushrooms Rich in Melatonin. Med Discoveries. 2. 10.52768/2993-1142/1075.
https://www.researchgate.net/publication/375439212_Homeostasis_of_Circadian_Rhythm_and_Therapeutic_Approaches_to_Manage_its_Related-Disorders_The_Case_of_Medicinal_Mushrooms_Rich_in_Melatonin



Νεφρά
554. Vaidya SR, Aeddula NR. Chronic Kidney Disease. [Updated 2024 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-
https://www.ncbi.nlm.nih.gov/books/NBK535404/

555. Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011). 2022 Apr;12(1):7-11. doi: 10.1016/j.kisu.2021.11.003. Epub 2022 Mar 18. PMID: 35529086; PMCID: PMC9073222.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9073222/

556. Lv JC, Zhang LX. Prevalence and Disease Burden of Chronic Kidney Disease. Adv Exp Med Biol. 2019;1165:3-15. doi: 10.1007/978-981-13-8871-2_1. PMID: 31399958.
https://pubmed.ncbi.nlm.nih.gov/31399958/

557. Francis, A., Harhay, M.N., Ong, A.C.M. et al. Chronic kidney disease and the global public health agenda: an international consensus. Nat Rev Nephrol 20, 473–485 (2024). https://doi.org/10.1038/s41581-024-00820-6
https://www.nature.com/articles/s41581-024-00820-6

558. Yacoub R, Habib H, Lahdo A, Al Ali R, Varjabedian L, Atalla G, Kassis Akl N, Aldakheel S, Alahdab S, Albitar S. Association between smoking and chronic kidney disease: a case control study. BMC Public Health. 2010 Nov 25;10:731. doi: 10.1186/1471-2458-10-731. PMID: 21108832; PMCID: PMC3004836.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3004836/

559. Fu YC, Xu ZL, Zhao MY, Xu K. The Association Between Smoking and Renal Function in People Over 20 Years Old. Front Med (Lausanne). 2022 Jun 3;9:870278. doi: 10.3389/fmed.2022.870278. PMID: 35721101; PMCID: PMC9205397.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9205397/

560. Lang, S.M., Schiffl, H. Smoking status, cadmium, and chronic kidney disease. Ren Replace Ther 10, 17 (2024). https://doi.org/10.1186/s41100-024-00533-3
https://rrtjournal.biomedcentral.com/articles/10.1186/s41100-024-00533-3

561. Chen TK, Knicely DH, Grams ME. Chronic Kidney Disease Diagnosis and Management: A Review. JAMA. 2019 Oct 1;322(13):1294-1304. doi: 10.1001/jama.2019.14745. PMID: 31573641; PMCID: PMC7015670.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7015670/

562. Diagnosis - Chronic kidney disease, UK NHS
https://www.nhs.uk/conditions/kidney-disease/diagnosis/

563. Singh AK, Narsipur SS. Cyclosporine: A Commentary on Brand versus Generic Formulation Exchange. J Transplant. 2011;2011:480642. doi: 10.1155/2011/480642. Epub 2011 Nov 17. PMID: 22174986; PMCID: PMC3235899.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3235899/

564. Park H. The emergence of mycophenolate mofetilin dermatology: from its roots in the world of organ transplantation to its versatile role in the dermatology treatment room. J Clin Aesthet Dermatol. 2011 Jan;4(1):18-27. PMID: 21278895; PMCID: PMC3030212.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3030212/

625. Tapia C, Nessel TA, Zito PM. Cyclosporine. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK482450/

626. Takeda A, Uchida K, Haba T, Tominaga Y, Katayama A, Yoshida A, Oikawa T, Morozumi K. Chronic cyclosporin nephropathy: long-term effects of cyclosporin on renal allografts. Clin Transplant. 2001;15 Suppl 5:22-9. doi: 10.1034/j.1399-0012.2001.0150s5022.x. PMID: 11791791.
https://pubmed.ncbi.nlm.nih.gov/11791791/

627. Jun Yu, Xiao Wei, Jinzhang Gao, Chun Wang, Wei Wei, Role of cyclosporin A in the treatment of kidney disease and nephrotoxicity, Toxicology, Volume 492, 2023, 153544, ISSN 0300-483X, https://doi.org/10.1016/j.tox.2023.153544.
https://www.sciencedirect.com/science/article/abs/pii/S0300483X23001300

628. Einollahi B, Teimoori M, A Systematic Review about an Advance in Cyclosporine Monitoring in Kidney Transplant Recipients.Nephro-Urol Mon.2017;9(4):e24989.https://doi.org/10.5812/numonthly.24989.
https://brieflands.com/articles/num-55530

629. Ng TH, Britton GJ, Hill EV, Verhagen J, Burton BR, Wraith DC. Regulation of adaptive immunity; the role of interleukin-10. Front Immunol. 2013 May 31;4:129. doi: 10.3389/fimmu.2013.00129. PMID: 23755052; PMCID: PMC3668291.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3668291/

630. Iyer SS, Cheng G. Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol. 2012;32(1):23-63. doi: 10.1615/critrevimmunol.v32.i1.30. PMID: 22428854; PMCID: PMC3410706.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3410706/

631. Kaliyaperumal, Y., Sivadasan, S. & Aiyalu, R. Contrast-Induced Nephropathy: An Overview. Dr. Sulaiman Al Habib Med J 5, 118–127 (2023). https://doi.org/10.1007/s44229-023-00040-3
https://link.springer.com/article/10.1007/s44229-023-00040-3

632. Mohammed NM, Mahfouz A, Achkar K, Rafie IM, Hajar R. Contrast-induced Nephropathy. Heart Views. 2013 Jul;14(3):106-16. doi: 10.4103/1995-705X.125926. PMID: 24696755; PMCID: PMC3969626.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3969626/

633. Modi K, Padala SA, Gupta M. Contrast-Induced Nephropathy. [Updated 2025 Jan 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan
https://www.ncbi.nlm.nih.gov/books/NBK448066/

634. R. Mehran, E. Nikolsky, Contrast-induced nephropathy: Definition, epidemiology, and patients at risk, Kidney International, Volume 69, Supplement 100, 2006, Pages S11-S15, ISSN 0085-2538, https://doi.org/10.1038/sj.ki.5000368.
https://www.sciencedirect.com/science/article/pii/S0085253815513872

635. Tascón, J.; Prieto, M.; Casanova, A.G.; Sanz, F.J.; Hernández Mezquita, M.A.; Barrueco Ferrero, M.; Gomez-Marcos, M.A.; Garcia-Ortiz, L.; Vicente-Vicente, L.; Morales, A.I.; et al. Early Diagnosis of Kidney Damage Associated with Tobacco Use: Preventive Application. J. Pers. Med. 2022, 12, 1032. https://doi.org/10.3390/jpm12071032
https://www.mdpi.com/2075-4426/12/7/1032

636. Charlene (Xiaoying) Deng, MD, PhD, MBA, FACP, FASN Assistant Professor of Medicine, Division of Nephrology, Hypertension and Transplantation, Thomas Jefferson University Hospital, Sidney Kimmel Medical College of Thomas Jefferson University
https://emedicine.medscape.com/article/246751-treatment

637. Ying M, Yang J, Huang Z, Ling Y, Wang B, Huang H, Li Q, Liu J, Liu Y, Chen Z. Association between malnutrition and contrast-associated acute kidney injury in congestive heart failure patients following coronary angiography. Front Nutr. 2022 Nov 17;9:937237. doi: 10.3389/fnut.2022.937237. PMID: 36466405; PMCID: PMC9713008.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9713008/

638. Liang J, Zhang L, Huang Z, He Y, Ling Y, Chen K, Ying M, Lin M, Li G, Liu J, Liu Y, Liang Y, Chen S and Hu Y (2022) Implications of Malnutrition on Contrast-Associated Acute Kidney Injury in Young and Old Patients Undergoing Percutaneous Coronary Intervention: A Multicenter Prospective Cohort. Front. Nutr. 8:795068. doi: 10.3389/fnut.2021.795068
https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2021.795068/full

639. Chen, Liling & Huang, Zhidong & Li, Weiguo & He, Yibo & Liang, Jingjing & Lu, Jin & Yang, Yanfang & Huang, Haozhang & Lin, Yihang & Lin, Rongwen & Lin, Mengfei & Liang, Yan & Hu, Yunzhao & Ye, Jianfeng & Hu, Yuying & Liu, Jin & Liu, Yong & Fang, Yong & Chen, Kaihong & Chen, Shiqun. (2022). Malnutrition and the risk for contrast-induced acute kidney injury in patients with coronary artery disease. International Urology and Nephrology. 54. 10.1007/s11255-021-02915-6.
https://www.researchgate.net/publication/352758623_Malnutrition_and_the_risk_for_contrast-induced_acute_kidney_injury_in_patients_with_coronary_artery_disease

640. Liang J, Zhang L, Huang Z, He Y, Ling Y, Chen K, Ying M, Lin M, Li G, Liu J, Liu Y, Liang Y, Chen S, Hu Y. Implications of Malnutrition on Contrast-Associated Acute Kidney Injury in Young and Old Patients Undergoing Percutaneous Coronary Intervention: A Multicenter Prospective Cohort. Front Nutr. 2022 Feb 8;8:795068. doi: 10.3389/fnut.2021.795068. PMID: 35211494; PMCID: PMC8861456.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8861456/

641. Ruth W. Mwangi, John M. Macharia, Isabel N. Wagara, Raposa L. Bence, The antioxidant potential of different edible and medicinal mushrooms, Biomedicine & Pharmacotherapy, Volume 147, 2022, 112621, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2022.112621.
https://www.sciencedirect.com/science/article/pii/S0753332222000099

642. Karunarathna, S. C., Prasannath, K., Lu, W., & Hapuarachchi, K. K. (2024). Ganoderma: bridging traditional wisdom with modern innovation in medicinal mushroom and dietary supplement industry. New Zealand Journal of Botany, 1–60. https://doi.org/10.1080/0028825X.2024.2410486
https://www.tandfonline.com/doi/abs/10.1080/0028825X.2024.2410486

643. Musa R, Rout P, Qurie A. Lupus Nephritis. [Updated 2025 Jan 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK499817/

644. Soo-Kyung Cho, Hyoungyoung Kim, Jung-Yong Han, Yena Jeon, Sun-Young Jung, Eun Jin Jang, Yoon-Kyoung Sung, Risk of end-stage renal disease in patients with early-onset lupus nephritis: A population-based cohort study, Seminars in Arthritis and Rheumatism, Volume 63, 2023, 152308, ISSN 0049-0172, https://doi.org/10.1016/j.semarthrit.2023.152308.
https://www.sciencedirect.com/science/article/abs/pii/S0049017223001506

645. Hoover PJ, Costenbader KH. Insights into the epidemiology and management of lupus nephritis from the US rheumatologist's perspective. Kidney Int. 2016 Sep;90(3):487-92. doi: 10.1016/j.kint.2016.03.042. Epub 2016 Jun 22. PMID: 27344205; PMCID: PMC5679458.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5679458/

646. A smoking gun for renal disease in patients with SLE?. Nat Rev Rheumatol 11, 562 (2015). https://doi.org/10.1038/nrrheum.2015.122
https://www.nature.com/articles/nrrheum.2015.122

647. Xu D, You X, Wang Z, Zeng Q, Xu J, Jiang L, Gong L, Wu F, Gu J, Tao Y, Chen J, Zhao J, Li M, Zhao Y, Zeng X; CSTAR co-authors. Chinese Systemic Lupus Erythematosus Treatment and Research Group Registry VI: Effect of Cigarette Smoking on the Clinical Phenotype of Chinese Patients with Systemic Lupus Erythematosus. PLoS One. 2015 Aug 17;10(8):e0134451. doi: 10.1371/journal.pone.0134451. PMID: 26280671; PMCID: PMC4539270.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4539270/

648. Islam MA, Khandker SS, Kotyla PJ, Hassan R. Immunomodulatory Effects of Diet and Nutrients in Systemic Lupus Erythematosus (SLE): A Systematic Review. Front Immunol. 2020 Jul 22;11:1477. doi: 10.3389/fimmu.2020.01477. PMID: 32793202; PMCID: PMC7387408.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7387408/

649. Krause KM, Serio AW, Kane TR, Connolly LE. Aminoglycosides: An Overview. Cold Spring Harb Perspect Med. 2016 Jun 1;6(6):a027029. doi: 10.1101/cshperspect.a027029. PMID: 27252397; PMCID: PMC4888811.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4888811/

650. Jose M. Lopez-Novoa, Yaremi Quiros, Laura Vicente, Ana I. Morales, Francisco J. Lopez-Hernandez, New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view, Kidney International, Volume 79, Issue 1, 2011, Pages 33-45, ISSN 0085-2538, https://doi.org/10.1038/ki.2010.337.
https://www.sciencedirect.com/science/article/pii/S0085253815546760

651. Swan SK. Aminoglycoside nephrotoxicity. Semin Nephrol. 1997 Jan;17(1):27-33. PMID: 9000547.
https://pubmed.ncbi.nlm.nih.gov/9000547/

652. Dobrek, L. A Synopsis of Current Theories on Drug-Induced Nephrotoxicity. Life 2023, 13, 325. https://doi.org/10.3390/life13020325
https://www.mdpi.com/2075-1729/13/2/325

661. Abramyan S, Hanlon M. Kidney Transplantation. [Updated 2023 Jan 2]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK567755/

662. Patrick Yoon Kim, Azarin Shoghi, Ghaneh Fananapazir, Renal Transplantation: Immediate and Late Complications, Radiologic Clinics of North America, Volume 61, Issue 5, 2023, Pages 809-820, ISSN 0033-8389, ISBN 9780443181771, https://doi.org/10.1016/j.rcl.2023.04.004.
https://www.sciencedirect.com/science/article/abs/pii/S0033838923001161

663. Naik RH, Shawar SH. Renal Transplantation Rejection. [Updated 2023 Feb 9]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK553074/

664. The National Kidney Federation, What is transplant rejection? March 2023
https://www.kidney.org.uk/what-is-transplant-rejection

665. Weinrauch LA, Claggett B, Liu J, Finn PV, Weir MR, Weiner DE, D'Elia JA. Smoking and outcomes in kidney transplant recipients: a post hoc survival analysis of the FAVORIT trial. Int J Nephrol Renovasc Dis. 2018 Apr 27;11:155-164. doi: 10.2147/IJNRD.S161001. PMID: 29760559; PMCID: PMC5937486.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5937486/

666. Salamah, Sovia1; Gomes Neto, Antonio Wouter1; Alkaff, Firas F.1,2; Kootstra-Ros, Jenny E.1; Touw, Daniel J.1; Franssen, Casper F.M.1; Bakker, Stephan J.L.1. Carboxyhemoglobin and Smoking Status in Kidney Transplant Recipients: TH-PO791. Journal of the American Society of Nephrology 35(10S):10.1681/ASN.2024s9tskgx2, October 2024. | DOI: 10.1681/ASN.2024s9tskgx2
https://journals.lww.com/jasn/fulltext/2024/10001/carboxyhemoglobin_and_smoking_status_in_kidney.1114.aspx

667. Christie Rampersad, Jason Bau, Ani Orchanian-Cheff, S. Joseph Kim, Impact of donor smoking history on kidney transplant recipient outcomes: A systematic review and meta-analysis, Transplantation Reviews, Volume 38, Issue 3, 2024, 100854, ISSN 0955-470X, https://doi.org/10.1016/j.trre.2024.100854.
https://www.sciencedirect.com/science/article/pii/S0955470X24000375

668. Khalil MAM, Tan J, Khamis S, Khalil MA, Azmat R, Ullah AR. Cigarette Smoking and Its Hazards in Kidney Transplantation. Adv Med. 2017;2017:6213814. doi: 10.1155/2017/6213814. Epub 2017 Jul 27. PMID: 28819637; PMCID: PMC5551477.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5551477/

669. Sara T. Stoler, Maria Chan, Steven J. Chadban, Nutrition in the Management of Kidney Transplant Recipients, Journal of Renal Nutrition, Volume 33, Issue 6, Supplement, 2023, Pages S67-S72, ISSN 1051-2276, https://doi.org/10.1053/j.jrn.2023.07.001.
https://www.sciencedirect.com/science/article/abs/pii/S1051227623001085

670. Stoler ST, Chan M, Chadban SJ. Nutrition in the Management of Kidney Transplant Recipients. J Ren Nutr. 2023 Nov;33(6S):S67-S72. doi: 10.1053/j.jrn.2023.07.001. Epub 2023 Jul 22. PMID: 37482148.
https://pubmed.ncbi.nlm.nih.gov/37482148/

690. Naik RH, Shawar SH. Renal Transplantation Rejection. 2023 Feb 9. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 31971715.
https://pubmed.ncbi.nlm.nih.gov/31971715/

691. Justiz Vaillant AA, Misra S, Fitzgerald BM. Acute Transplantation Rejection. [Updated 2024 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK535410/

692. Maria Sandovici, Leo E. Deelman, Dick de Zeeuw, Harry van Goor, Robert H. Henning, Immune modulation and graft protection by gene therapy in kidney transplantation, European Journal of Pharmacology, Volume 585, Issues 2–3, 2008, Pages 261-269, ISSN 0014-2999, https://doi.org/10.1016/j.ejphar.2008.02.087.
https://www.sciencedirect.com/science/article/abs/pii/S0014299908002811

693. Oweira H, Ramouz A, Ghamarnejad O, Khajeh E, Ali-Hasan-Al-Saegh S, Nikbakhsh R, Reißfelder C, Rahbari N, Mehrabi A, Sadeghi M. Risk Factors of Rejection in Renal Transplant Recipients: A Narrative Review. J Clin Med. 2022 Mar 3;11(5):1392. doi: 10.3390/jcm11051392. PMID: 35268482; PMCID: PMC8911293.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8911293/

694. Alasfar, S.; Kodali, L.; Schinstock, C.A. Current Therapies in Kidney Transplant Rejection. J. Clin. Med. 2023, 12, 4927. https://doi.org/10.3390/jcm12154927
https://www.mdpi.com/2077-0383/12/15/4927

695. Aref A, Sharma A, Halawa A. Smoking in Renal Transplantation; Facts Beyond Myth. World J Transplant. 2017 Apr 24;7(2):129-133. doi: 10.5500/wjt.v7.i2.129. PMID: 28507915; PMCID: PMC5409912.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5409912/

696  Arnaud Devresse, Sophie Gohy, Arnaud Robert, Nada Kanaan, How to manage cigarette smoking in kidney transplant candidates and recipients?, Clinical Kidney Journal, Volume 14, Issue 11, November 2021, Pages 2295–2303, https://doi.org/10.1093/ckj/sfab072
https://academic.oup.com/ckj/article/14/11/2295/6204102

697. Simone A. Joosten, YVO W.J. Sijpkens, Cees van Kooten, Leendert C. Paul, Chronic renal allograft rejection: Pathophysiologic considerations, Kidney International, Volume 68, Issue 1, 2005, Pages 1-13, ISSN 0085-2538, https://doi.org/10.1111/j.1523-1755.2005.00376.x.
https://www.sciencedirect.com/science/article/pii/S0085253815508090

698. Sung RS, Althoen M, Howell TA, Ojo AO, Merion RM. Excess risk of renal allograft loss associated with cigarette smoking. Transplantation. 2001 Jun 27;71(12):1752-7. doi: 10.1097/00007890-200106270-00009. PMID: 11455254.
https://pubmed.ncbi.nlm.nih.gov/11455254/

699. Agarwal, P. K., Hellemons, M. E., Zelle, D. M., van Ree, R. M., van den Born, J., van der Heide, J. J. H., Gans, R. O. B., van Son, W. J., Navis, G., & Bakker, S. J. L. (2011). Smoking Is a Risk Factor for Graft Failure and Mortality after Renal Transplantation. American Journal of Nephrology, 34(1), 26-31. https://doi.org/10.1159/000328903
https://pure.eur.nl/en/publications/smoking-is-a-risk-factor-for-graft-failure-and-mortality-after-re

700. Nourbala, Mohammad & Nemati, Eghlim & Rostami, Zohreh & Einollahi, Behzad. (2011). Impact of Cigarette Smoking on Kidney Transplant Recipients A Systematic Review. Iranian journal of kidney diseases. 5. 141-8.
https://www.researchgate.net/publication/51082216_Impact_of_Cigarette_Smoking_on_Kidney_Transplant_Recipients_A_Systematic_Review

701. Agarwal PK, Hellemons ME, Zelle DM, van Ree RM, van den Born J, van der Heide JJ, Gans RO, van Son WJ, Navis G, Bakker SJ. Smoking is a risk factor for graft failure and mortality after renal transplantation. Am J Nephrol. 2011;34(1):26-31. doi: 10.1159/000328903. Epub 2011 Jun 9. PMID: 21659736.
https://pubmed.ncbi.nlm.nih.gov/21659736/

702. Shamsudheen, M. P.; Kuchay, Abid; Gupta, Vijay Chander; Tiwari, Isha; Karthik, Raja,*; Das, Uttara; Guditi, Swarnalatha; Taduri, Gangadhar. Allograft Rejection in Kidney Transplantation – A Retrospective Study of Impact on Graft and Patient Outcome. Indian Journal of Transplantation 16(4):p 371-376, Oct–Dec 2022. | DOI: 10.4103/ijot.ijot_93_21
https://journals.lww.com/ijjt/fulltext/2022/16040/allograft_rejection_in_kidney_transplantation___a.4.aspx

703. Cyrino LG, Galpern J, Moore L, Borgi L, Riella LV. A Narrative Review of Dietary Approaches for Kidney Transplant Patients. Kidney Int Rep. 2021 Apr 27;6(7):1764-1774. doi: 10.1016/j.ekir.2021.04.009. PMID: 34307973; PMCID: PMC8258457.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8258457/

704. Abdulla K. Salahudeen, Thomas H. Hostetter, Susan K. Raatz, Mark E. Rosenberg, Effects of dietary protein in patients with chronic renal transplant rejection, Kidney International, Volume 41, Issue 1, 1992, Pages 183-190, ISSN 0085-2538, https://doi.org/10.1038/ki.1992.25.
https://www.sciencedirect.com/science/article/pii/S0085253815574462

705. Sengupta P, Chaudhuri A, Rathore K, Biswas S. Nutritional management of kidney transplant recipient. Proceedings of Singapore Healthcare. 2025;34. doi:10.1177/20101058251327810
https://journals.sagepub.com/doi/10.1177/20101058251327810



Ξηροφθαλμία
582. Golden MI, Meyer JJ, Zeppieri M, Patel BC. Dry Eye Syndrome. 2024 Feb 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 29262012.
https://pubmed.ncbi.nlm.nih.gov/29262012/

583. Golden MI, Meyer JJ, Zeppieri M, et al. Dry Eye Syndrome. [Updated 2024 Feb 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK470411/
https://www.ncbi.nlm.nih.gov/books/NBK470411/

584. Yamada M, Mizuno Y, Shigeyasu C. Impact of dry eye on work productivity. Clinicoecon Outcomes Res. 2012;4:307-12. doi: 10.2147/CEOR.S36352. Epub 2012 Oct 10. PMID: 23091391; PMCID: PMC3471464.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3471464/

585. Guo OD LW, Akpek E. The negative effects of dry eye disease on quality of life and visual function. Turk J Med Sci. 2020 Nov 3;50(SI-2):1611-1615. doi: 10.3906/sag-2002-143. PMID: 32283910; PMCID: PMC7672346.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7672346/

586. Wróbel-Dudzińska D, Osial N, Stępień PW, Gorecka A, Żarnowski T. Prevalence of Dry Eye Symptoms and Associated Risk Factors among University Students in Poland. Int J Environ Res Public Health. 2023 Jan 11;20(2):1313. doi: 10.3390/ijerph20021313. PMID: 36674068; PMCID: PMC9859544.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9859544/

587. He Q, Chen Z, Xie C, Liu L and Wei R (2022) The Association Between Dry Eye Disease With Depression, Anxiety and Sleep Disturbance During COVID-19. Front. Psychiatry 12:802302. doi: 10.3389/fpsyt.2021.802302
https://www.frontiersin.org/journals/psychiatry/articles/10.3389/fpsyt.2021.802302/full

588. Yang, K., Zhang, H., Wang, Y. et al. Evaluating the impact of smoking on the risk of dry eye disease: a two-sample Mendelian randomization study. Sci Rep 14, 32043 (2024). https://doi.org/10.1038/s41598-024-83795-5
https://www.nature.com/articles/s41598-024-83795-5

589. Solberg Y, Rosner M, Belkin M. The association between cigarette smoking and ocular diseases. Surv Ophthalmol. 1998 May-Jun;42(6):535-47. doi: 10.1016/s0039-6257(98)00002-2. PMID: 9635902.
https://pubmed.ncbi.nlm.nih.gov/9635902/

590. Xu L, Zhang W, Zhu XY, Suo T, Fan XQ, Fu Y. Smoking and the risk of dry eye: a Meta-analysis. Int J Ophthalmol. 2016 Oct 18;9(10):1480-1486. doi: 10.18240/ijo.2016.10.19. PMID: 27803868; PMCID: PMC5075666.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5075666/

591. Areesanan A, Wasilewicz A, Nicolay S, Grienke U, Zimmermann-Klemd AM, Rollinger JM and Gründemann C (2025) Evaluation of in vitro pharmacological activities of medicinal mushrooms in the context of dry eye disease. Front. Pharmacol. 16:1557359. doi: 10.3389/fphar.2025.1557359
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2025.1557359/full

592. El Barche, FZ., Benyoussef, AA., El Habib Daho, M. et al. Automated tear film break-up time measurement for dry eye diagnosis using deep learning. Sci Rep 14, 11723 (2024). https://doi.org/10.1038/s41598-024-62636-5
https://www.nature.com/articles/s41598-024-62636-5



Ενδοφθάλμια πίεση
1. Dietze J, Blair K, Zeppieri M, et al. Glaucoma. [Updated 2024 Mar 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK538217/

2. Da Zhao, Vickie H. Y. Wong, Christine T. O. Nguyen, Andrew I. Jobling, Erica L. Fletcher, Algis J. Vingrys, Bang V. Bui; Reversibility of Retinal Ganglion Cell Dysfunction From Chronic IOP Elevation. Invest. Ophthalmol. Vis. Sci. 2019;60(12):3878-3886. https://doi.org/10.1167/iovs.19-27113.
https://iovs.arvojournals.org/article.aspx?articleid=2751565

3. Glaucoma, american optometric association (aoa)
https://www.aoa.org/healthy-eyes/eye-and-vision-conditions/glaucoma



Σύνδρομο πολυκυστικών ωοθηκών
464. Shukla A, Rasquin LI, Anastasopoulou C. Polycystic Ovarian Syndrome. [Updated 2025 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK459251/

465.  Bohsas, H., Alibrahim, H., Swed, S., Abouainain, Y., Aljabali, A., Kazan, L., … Khandaker, M. U. (2024). Prevalence and knowledge of polycystic ovary syndrome (PCOS) and health-related practices among women of Syria: a cross-sectional study. Journal of Psychosomatic Obstetrics & Gynecology, 45(1). https://doi.org/10.1080/0167482X.2024.2318194
https://www.tandfonline.com/doi/full/10.1080/0167482X.2024.2318194#abstract

466. Deswal R, Narwal V, Dang A, Pundir CS. The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. J Hum Reprod Sci. 2020 Oct-Dec;13(4):261-271. doi: 10.4103/jhrs.JHRS_95_18. Epub 2020 Dec 28. PMID: 33627974; PMCID: PMC7879843.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7879843/

467. Singh S, Pal N, Shubham S, Sarma DK, Verma V, Marotta F, Kumar M. Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics. J Clin Med. 2023 Feb 11;12(4):1454. doi: 10.3390/jcm12041454. PMID: 36835989; PMCID: PMC9964744.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9964744/

468. Johnson JE, Daley D, Tarta C, Stanciu PI. Risk of endometrial cancer in patients with polycystic ovarian syndrome: A meta‑analysis. Oncol Lett. 2023 Mar 8;25(4):168. doi: 10.3892/ol.2023.13754. PMID: 36960190; PMCID: PMC10028221.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10028221/

469. Liao WT, Huang JY, Lee MT, Yang YC, Wu CC. Higher risk of type 2 diabetes in young women with polycystic ovary syndrome: A 10-year retrospective cohort study. World J Diabetes. 2022 Mar 15;13(3):240-250. doi: 10.4239/wjd.v13.i3.240. PMID: 35432752; PMCID: PMC8984565.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8984565/

470. Yasmin A, Roychoudhury S, Paul Choudhury A, Ahmed ABF, Dutta S, Mottola F, Verma V, Kalita JC, Kumar D, Sengupta P, Kolesarova A. Polycystic Ovary Syndrome: An Updated Overview Foregrounding Impacts of Ethnicities and Geographic Variations. Life (Basel). 2022 Nov 25;12(12):1974. doi: 10.3390/life12121974. PMID: 36556340; PMCID: PMC9785838.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9785838/

471. Cupisti S, Häberle L, Dittrich R, Oppelt PG, Reissmann C, Kronawitter D, Beckmann MW, Mueller A. Smoking is associated with increased free testosterone and fasting insulin levels in women with polycystic ovary syndrome, resulting in aggravated insulin resistance. Fertil Steril. 2010 Jul;94(2):673-7. doi: 10.1016/j.fertnstert.2009.03.062. Epub 2009 Apr 25. PMID: 19394003.
https://pubmed.ncbi.nlm.nih.gov/19394003/

472. Yang, Y., Zhang, H., Huang, BY. et al. Relationship between smoking, excessive androgen and negative emotions in women with polycystic ovary syndrome (PCOS). J Ovarian Res 17, 211 (2024). https://doi.org/10.1186/s13048-024-01541-x
https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-024-01541-x

473. Dason ES, Koshkina O, Chan C, Sobel M. Diagnosis and management of polycystic ovarian syndrome. CMAJ. 2024 Jan 28;196(3):E85-E94. doi: 10.1503/cmaj.231251. Erratum in: CMAJ. 2024 Mar 3;196(8):E269. doi: 10.1503/cmaj.240216. Erratum in: CMAJ. 2024 Mar 17;196(10):E351. doi: 10.1503/cmaj.240303. PMID: 38286488; PMCID: PMC10833093.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10833093/

474. Nikokavoura EA, Johnston KL, Broom J, Wrieden WL, Rolland C. Weight loss for women with and without polycystic ovary syndrome following a very low-calorie diet in a community-based setting with trained facilitators for 12 weeks. Diabetes Metab Syndr Obes. 2015 Oct 14;8:495-503. doi: 10.2147/DMSO.S85134. PMID: 26508882; PMCID: PMC4610794.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4610794/

475. Szczuko M, Kikut J, Szczuko U, Szydłowska I, Nawrocka-Rutkowska J, Ziętek M, Verbanac D, Saso L. Nutrition Strategy and Life Style in Polycystic Ovary Syndrome-Narrative Review. Nutrients. 2021 Jul 18;13(7):2452. doi: 10.3390/nu13072452. PMID: 34371961; PMCID: PMC8308732.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8308732/

739. Dennett CC, Simon J. The role of polycystic ovary syndrome in reproductive and metabolic health: overview and approaches for treatment. Diabetes Spectr. 2015 May;28(2):116-20. doi: 10.2337/diaspect.28.2.116. PMID: 25987810; PMCID: PMC4433074.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4433074/

740. May 15, 2024, Diabetes and Polycystic Ovary Syndrome (PCOS), u.s. centers for disease control and prevention
https://www.cdc.gov/diabetes/risk-factors/pcos-polycystic-ovary-syndrome.html

741. Scicchitano P, Dentamaro I, Carbonara R, Bulzis G, Dachille A, Caputo P, Riccardi R, Locorotondo M, Mandurino C, Matteo Ciccone M. Cardiovascular Risk in Women With PCOS. Int J Endocrinol Metab. 2012 Fall;10(4):611-8. doi: 10.5812/ijem.4020. Epub 2012 Sep 30. PMID: 23843832; PMCID: PMC3693634.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3693634/

1.  Xu D, Lu M, Liu Y, et al. An Analysis of the Clinical Medication Rules of Traditional Chinese Medicine for Polycystic Ovary Syndrome Based on Data Mining. Evidence-based Complementary and Alternative Medicine : Ecam. 2023 ;2023:6198001. DOI: 10.1155/2023/6198001. PMID: 36865746; PMCID: PMC9974250.
https://europepmc.org/article/MED/36865746

2. Lim SS, Hutchison SK, Van Ryswyk E, et al. Lifestyle changes in women with polycystic ovary syndrome. The Cochrane Database of Systematic Reviews. 2019 Mar;3:CD007506. DOI: 10.1002/14651858.cd007506.pub4. PMID: 30921477; PMCID: PMC6438659.
https://europepmc.org/article/PMC/6438659

3. Azziz R, Carmina E, Chen Z, Dunaif A, Laven JS, Legro RS, Lizneva D, Natterson-Horowtiz B, Teede HJ, Yildiz BO. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016 Aug 11;2:16057. doi: 10.1038/nrdp.2016.57. PMID: 27510637.
https://pubmed.ncbi.nlm.nih.gov/27510637/

4. Sirmans SM, Pate KA. Epidemiology, diagnosis, and management of polycystic ovary syndrome. Clin Epidemiol. 2013 Dec 18;6:1-13. doi: 10.2147/CLEP.S37559. PMID: 24379699; PMCID: PMC3872139.
https://pubmed.ncbi.nlm.nih.gov/24379699/

5. Doretto L, Mari FC, Chaves AC. Polycystic Ovary Syndrome and Psychotic Disorder. Front Psychiatry. 2020 Jun 10;11:543. doi: 10.3389/fpsyt.2020.00543. PMID: 32587538; PMCID: PMC7297942.
https://www.frontiersin.org/articles/10.3389/fpsyt.2020.00543/full

6. Teede, H., Deeks, A. & Moran, L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med 8, 41 (2010). https://doi.org/10.1186/1741-7015-8-41
https://bmcmedicine.biomedcentral.com/articles/10.1186/1741-7015-8-41

7. De Leo, V., Musacchio, M.C., Cappelli, V. et al. Genetic, hormonal and metabolic aspects of PCOS: an update. Reprod Biol Endocrinol 14, 38 (2016). https://doi.org/10.1186/s12958-016-0173-x
https://rbej.biomedcentral.com/articles/10.1186/s12958-016-0173-x

8. Sadeeqa, Saleha; Mustafa, Tehreem; Latif, Sumaira. Polycystic Ovarian Syndrome–Related Depression in Adolescent Girls: A Review. Journal of Pharmacy And Bioallied Sciences 10(2):p 55-59, Apr–Jun 2018. | DOI: 10.4103/JPBS.JPBS_1_18
https://journals.lww.com/jpbs/Fulltext/2018/10020/Polycystic_Ovarian_Syndrome_Related_Depression_in.1.aspx

9. Cena H, Chiovato L, Nappi RE. Obesity, Polycystic Ovary Syndrome, and Infertility: A New Avenue for GLP-1 Receptor Agonists. J Clin Endocrinol Metab. 2020 Aug 1;105(8):e2695–709. doi: 10.1210/clinem/dgaa285. PMID: 32442310; PMCID: PMC7457958.
https://pubmed.ncbi.nlm.nih.gov/32442310/

10.  Ding J, Shanshan M, Mengcheng C, Danying Z, Jin Y. Integrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome. Evidence-based Complementary and Alternative Medicine : Ecam. 2022 ;2022:2635375. DOI: 10.1155/2022/2635375. PMID: 35600955; PMCID: PMC9122682.
https://europepmc.org/article/PMC/9122682

11. Rong A, Ta N, E L, Meng W. Add-on effect of the Guizhi Fuling formula for management of reduced fertility potential in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials. Front Endocrinol (Lausanne). 2023 Apr 18;13:995106. doi: 10.3389/fendo.2022.995106. PMID: 37143960; PMCID: PMC10153095.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10153095/

12. Luo J, Nie RQ, Lin LY. Influence of taie-35 and clomifen combined with laurel cocos poria pill on the pregnancy and psychological state of polycystic ovary syndrome patients. Drug Eval Res (2018) 41(7):1300–3. doi:  10.7501/j.issn.1674-6376.2018.07.028
https://www.cabdirect.org/globalhealth/abstract/20203190560

13. Liu M, Zhu H, Hu X, Zhu Y, Chen H. Efficacy of different forms of Guizhi Fuling Wan on reproduction and metabolism in women with polycystic ovary syndrome: A protocol for a meta-analysis of randomized controlled trials. Medicine (Baltimore). 2020 Oct 30;99(44):e22954. doi: 10.1097/MD.0000000000022954. PMID: 33126363; PMCID: PMC7598780.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7598780/

14. Lizneva D, Suturina L, Walker W, Brakta S, Gavrilova-Jordan L, Azziz R. Criteria, prevalence, and phenotypes of polycystic ovary syndrome. Fertil Steril. 2016 Jul;106(1):6-15. doi: 10.1016/j.fertnstert.2016.05.003. Epub 2016 May 24. PMID: 27233760.
https://pubmed.ncbi.nlm.nih.gov/27233760/

15. Jabeen A, Yamini V, Rahman Amberina A, Dinesh Eshwar M, Vadakedath S, Begum GS, Kandi V. Polycystic Ovarian Syndrome: Prevalence, Predisposing Factors, and Awareness Among Adolescent and Young Girls of South India. Cureus. 2022 Aug 12;14(8):e27943. doi: 10.7759/cureus.27943. PMID: 36120281; PMCID: PMC9464521.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9464521/

16. Deswal R, Narwal V, Dang A, Pundir CS. The Prevalence of Polycystic Ovary Syndrome: A Brief Systematic Review. J Hum Reprod Sci. 2020 Oct-Dec;13(4):261-271. doi: 10.4103/jhrs.JHRS_95_18. Epub 2020 Dec 28. PMID: 33627974; PMCID: PMC7879843.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879843/

17. The Lancet Regional Health-Europe. Polycystic ovary syndrome: What more can be done for patients? Lancet Reg Health Eur. 2022 Oct 3;21:100524. doi: 10.1016/j.lanepe.2022.100524. PMID: 36406775; PMCID: PMC9666923.
https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(22)00220-4/fulltext



Λειτουργία των Τ λεμφοκυττάρων
503. Glik A, Douvdevani A. T lymphocytes: the "cellular" arm of acquired immunity in the peritoneum. Perit Dial Int. 2006 Jul-Aug;26(4):438-48. PMID: 16881338.
https://pubmed.ncbi.nlm.nih.gov/16881338/

504. Sun, L., Su, Y., Jiao, A. et al. T cells in health and disease. Sig Transduct Target Ther 8, 235 (2023). https://doi.org/10.1038/s41392-023-01471-y
https://www.nature.com/articles/s41392-023-01471-y

505. Klimpel GR. Immune Defenses. In: Baron S, editor. Medical Microbiology. 4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 50.
https://www.ncbi.nlm.nih.gov/books/NBK8423/

506. Anisha Singha Deo,  Shrijana, Sruthika S.U, Shreya Karun, Kashish Bisaria, Koustav Sarkar, Participation of T cells in generating immune protection against cancers, Pathology - Research and Practice, Volume 262, 2024, 155534, ISSN 0344-0338, https://doi.org/10.1016/j.prp.2024.155534.
https://www.sciencedirect.com/science/article/abs/pii/S034403382400445X

507. Chen C, Liu X, Chang CY, Wang HY, Wang RF. The Interplay between T Cells and Cancer: The Basis of Immunotherapy. Genes (Basel). 2023 Apr 28;14(5):1008. doi: 10.3390/genes14051008. PMID: 37239368; PMCID: PMC10218245.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10218245/

508. Ruiz-Argüelles A. T lymphocytes in autoimmunity. In: Anaya JM, Shoenfeld Y, Rojas-Villarraga A, et al., editors. Autoimmunity: From Bench to Bedside [Internet]. Bogota (Colombia): El Rosario University Press; 2013 Jul 18. Chapter 7.
https://www.ncbi.nlm.nih.gov/books/NBK459477/

509. Janeway CA Jr, Travers P, Walport M, et al. Immunobiology: The Immune System in Health and Disease. 5th edition. New York: Garland Science; 2001. Generation of lymphocytes in bone marrow and thymus.
https://www.ncbi.nlm.nih.gov/books/NBK27123/

510. Kono M, Takagi Y, Kawauchi S, Wada A, Morikawa T, Funakoshi K. Non-activated T and B lymphocytes become morphologically distinguishable after detergent treatment. Cytometry A. 2013 Apr;83(4):396-402. doi: 10.1002/cyto.a.22262. Epub 2013 Feb 11. PMID: 23401265.
https://pubmed.ncbi.nlm.nih.gov/23401265/

511. Hernandez CP, Morrow K, Velasco C, Wyczechowska DD, Naura AS, Rodriguez PC. Effects of cigarette smoke extract on primary activated T cells. Cell Immunol. 2013 Mar;282(1):38-43. doi: 10.1016/j.cellimm.2013.04.005. Epub 2013 Apr 22. PMID: 23665673; PMCID: PMC3676722.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3676722/

512. Saint-André, V., Charbit, B., Biton, A. et al. Smoking changes adaptive immunity with persistent effects. Nature 626, 827–835 (2024). https://doi.org/10.1038/s41586-023-06968-8
https://www.nature.com/articles/s41586-023-06968-8

513. Collins N. Dietary Regulation of Memory T Cells. Int J Mol Sci. 2020 Jun 19;21(12):4363. doi: 10.3390/ijms21124363. PMID: 32575427; PMCID: PMC7352243.
https://pubmed.ncbi.nlm.nih.gov/32575427/

514. Cohen S, Danzaki K, MacIver NJ. Nutritional effects on T-cell immunometabolism. Eur J Immunol. 2017 Feb;47(2):225-235. doi: 10.1002/eji.201646423. Epub 2017 Jan 24. PMID: 28054344; PMCID: PMC5342627.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5342627/

515. Guggenheim AG, Wright KM, Zwickey HL. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44. PMID: 26770080; PMCID: PMC4684115.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4684115/

516.  Hetland, Geir, Johnson, Egil, Lyberg, Torstein, Kvalheim, Gunnar, The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation, Advances in Pharmacological and Pharmaceutical Sciences, 2011, 157015, 10 pages, 2011. https://doi.org/10.1155/2011/157015
https://onlinelibrary.wiley.com/doi/10.1155/2011/157015



Υποθυρεοειδισμός
1. Study Design 101: Case Report, george washington university
https://guides.himmelfarb.gwu.edu/studydesign101/case-report

2. Albrecht J, Werth VP, Bigby M. The role of case reports in evidence-based practice, with suggestions for improving their reporting. J Am Acad Dermatol. 2009 Mar;60(3):412-8. doi: 10.1016/j.jaad.2008.10.023. PMID: 19231639; PMCID: PMC7382892.
https://pubmed.ncbi.nlm.nih.gov/19231639/

3. Vandenbroucke JP. In defense of case reports and case series. Ann Intern Med. 2001 Feb 20;134(4):330-4. doi: 10.7326/0003-4819-134-4-200102200-00017. PMID: 11182844.
https://pubmed.ncbi.nlm.nih.gov/11182844/



Αντιφλεγμονώδη δράση
517. Pahwa R, Goyal A, Jialal I. Chronic Inflammation. [Updated 2023 Aug 7]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK493173/

518. Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J, Li Y, Wang X, Zhao L. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2017 Dec 14;9(6):7204-7218. doi: 10.18632/oncotarget.23208. PMID: 29467962; PMCID: PMC5805548.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5805548/

519. Sarah Kraus, Nadir Arber, Inflammation and colorectal cancer, Current Opinion in Pharmacology, Volume 9, Issue 4, 2009, Pages 405-410, ISSN 1471-4892, https://doi.org/10.1016/j.coph.2009.06.006.
https://www.sciencedirect.com/science/article/abs/pii/S1471489209000812

520. Maddipati KR (2024) Distinct etiology of chronic inflammation – implications on degenerative diseases and cancer therapy. Front. Immunol. 15:1460302. doi: 10.3389/fimmu.2024.1460302
https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2024.1460302/full

521. Cacciatore, S.; Andaloro, S.; Bernardi, M.; Oterino Manzanas, A.; Spadafora, L.; Figliozzi, S.; Asher, E.; Rana, J.S.; Ecarnot, F.; Gragnano, F.; et al. Chronic Inflammatory Diseases and Cardiovascular Risk: Current Insights and Future Strategies for Optimal Management. Int. J. Mol. Sci. 2025, 26, 3071. https://doi.org/10.3390/ijms26073071
https://www.mdpi.com/1422-0067/26/7/3071

522. Placha D, Jampilek J. Chronic Inflammatory Diseases, Anti-Inflammatory Agents and Their Delivery Nanosystems. Pharmaceutics. 2021 Jan 6;13(1):64. doi: 10.3390/pharmaceutics13010064. PMID: 33419176; PMCID: PMC7825503.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7825503/

523. Alejandra P. Garza, Lorena Morton, Éva Pállinger, Edit I. Buzás, Stefanie Schreiber, Björn H. Schott, Ildiko Rita Dunay, Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration, Brain, Behavior, & Immunity - Health, Volume 28, 2023, 100597, ISSN 2666-3546, https://doi.org/10.1016/j.bbih.2023.100597.
https://www.sciencedirect.com/science/article/pii/S266635462300011X

524. Lee J, Taneja V, Vassallo R. Cigarette smoking and inflammation: cellular and molecular mechanisms. J Dent Res. 2012 Feb;91(2):142-9. doi: 10.1177/0022034511421200. Epub 2011 Aug 29. PMID: 21876032; PMCID: PMC3261116.
https://pmc.ncbi.nlm.nih.gov/articles/PMC3261116/

525. Yan S, Ma Z, Jiao M, Wang Y, Li A and Ding S (2021) Effects of Smoking on Inflammatory Markers in a Healthy Population as Analyzed via the Gut Microbiota. Front. Cell. Infect. Microbiol. 11:633242. doi: 10.3389/fcimb.2021.633242
https://www.frontiersin.org/journals/cellular-and-infection-microbiology/articles/10.3389/fcimb.2021.633242/full

526. Smoking Can Be Hazardous to Your Joints, Linda Rath | April 20, 2023, Arthritis Foundation
https://www.arthritis.org/diseases/more-about/smoking-can-be-hazardous-to-joints

527. Stumpf F, Keller B, Gressies C, Schuetz P. Inflammation and Nutrition: Friend or Foe? Nutrients. 2023 Feb 25;15(5):1159. doi: 10.3390/nu15051159. PMID: 36904164; PMCID: PMC10005147.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10005147/

528. Scheiber A, Mank V. Anti-Inflammatory Diets. [Updated 2023 Oct 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-.
https://www.ncbi.nlm.nih.gov/books/NBK597377/

529. Elsayed EA, El Enshasy H, Wadaan MA, Aziz R. Mushrooms: a potential natural source of anti-inflammatory compounds for medical applications. Mediators Inflamm. 2014;2014:805841. doi: 10.1155/2014/805841. Epub 2014 Nov 23. PMID: 25505823; PMCID: PMC4258329.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4258329/

530. Du, Bin & Zhu, Fengmei & Xu, Baojun. (2018). An insight into the anti-inflammatory properties of edible and medicinal mushrooms. Journal of Functional Foods. 47. 10.1016/j.jff.2018.06.003.
https://www.researchgate.net/publication/325732957_An_insight_into_the_anti-inflammatory_properties_of_edible_and_medicinal_mushrooms

531. Venturella G, Ferraro V, Cirlincione F, Gargano ML. Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials. Int J Mol Sci. 2021 Jan 10;22(2):634. doi: 10.3390/ijms22020634. PMID: 33435246; PMCID: PMC7826851.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7826851/

532. Xia Y, Wang D, Li J, Chen M, Wang D, Jiang Z, Liu B. Compounds purified from edible fungi fight against chronic inflammation through oxidative stress regulation. Front Pharmacol. 2022 Sep 9;13:974794. doi: 10.3389/fphar.2022.974794. Erratum in: Front Pharmacol. 2023 Jan 05;13:1081523. doi: 10.3389/fphar.2022.1081523. PMID: 36160418; PMCID: PMC9500316.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9500316/

533. Hetland G, Johnson E, Bernardshaw SV, Grinde B. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID-19 and its pneumonic superinfection and complicating inflammation? Scand J Immunol. 2021 Jan;93(1):e12937. doi: 10.1111/sji.12937. Epub 2020 Jul 29. PMID: 32657436; PMCID: PMC7404338.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7404338/

534. Phillips, J.M.; Ooi, S.L.; Pak, S.C. Health-Promoting Properties of Medicinal Mushrooms and Their Bioactive Compounds for the COVID-19 Era—An Appraisal: Do the Pro-Health Claims Measure Up? Molecules 2022, 27, 2302. https://doi.org/10.3390/molecules27072302
https://www.mdpi.com/1420-3049/27/7/2302

535. Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005 Jun 9;2005(2):63-80. doi: 10.1155/MI.2005.63. PMID: 16030389; PMCID: PMC1160565.
https://pmc.ncbi.nlm.nih.gov/articles/PMC1160565/

536. Emma Camilleri, Renald Blundell, Bikash Baral, Tomasz M. Karpinski, Edlira Aruci, Omar M. Atrooz, A brief overview of the medicinal and nutraceutical importance of Inonotus obliquus (chaga) mushrooms, Heliyon, Volume 10, Issue 15, 2024, e35638, ISSN 2405-8440, https://doi.org/10.1016/j.heliyon.2024.e35638.
https://www.sciencedirect.com/science/article/pii/S2405844024116696

537. Yin Z, Zhang J, Qin J, Guo L, Guo Q, Kang W, Ma C and Chen L (2024) Anti-inflammatory properties of polysaccharides from edible fungi on health-promotion: a review. Front. Pharmacol. 15:1447677. doi: 10.3389/fphar.2024.1447677
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2024.1447677/full

538. Adekunle Rowaiye, Olobayotan Ifeyomi Wilfred, Olukemi Adejoke Onuh, Doofan Bur, Solomon Oni, Ezinne Janefrances Nwonu, Gordon Ibeanu, Angus Nnamdi Oli, Timipanipiri ThankGod Wood, Modulatory Effects of Mushrooms on the Inflammatory Signaling Pathways and Pro-inflammatory Mediators, Clinical Complementary Medicine and Pharmacology, Volume 2, Issue 4, 2022, 100037, ISSN 2772-3712, https://doi.org/10.1016/j.ccmp.2022.100037.
https://www.sciencedirect.com/science/article/pii/S2772371222000183



Φοιτητικές εξετάσεις
352.  Kumar B, Shah MAA, Kumari R, et al. Depression, Anxiety, and Stress Among Final-year Medical Students. Cureus. 2019 Mar;11(3):e4257. DOI: 10.7759/cureus.4257. PMID: 31139516; PMCID: PMC6519980.
https://europepmc.org/article/MED/31139516

353. Shamsuddin K, Fadzil F, Ismail WS, Shah SA, Omar K, Muhammad NA, Jaffar A, Ismail A, Mahadevan R. Correlates of depression, anxiety and stress among Malaysian university students. Asian J Psychiatr. 2013 Aug;6(4):318-23. doi: 10.1016/j.ajp.2013.01.014. Epub 2013 Mar 1. PMID: 23810140.
https://pubmed.ncbi.nlm.nih.gov/23810140/

354. Regehr C, Glancy D, Pitts A. Interventions to reduce stress in university students: a review and meta-analysis. J Affect Disord. 2013 May 15;148(1):1-11. doi: 10.1016/j.jad.2012.11.026. Epub 2012 Dec 13. PMID: 23246209.
https://pubmed.ncbi.nlm.nih.gov/23246209/

355.  Lattie EG, Adkins EC, Winquist N, et al. Digital Mental Health Interventions for Depression, Anxiety, and Enhancement of Psychological Well-Being Among College Students: Systematic Review. Journal of Medical Internet Research. 2019 Jul;21(7):e12869. DOI: 10.2196/12869. PMID: 31333198; PMCID: PMC6681642.
https://europepmc.org/article/MED/31333198

356.  Liu CH, Stevens C, Wong SHM, Yasui M, Chen JA. The prevalence and predictors of mental health diagnoses and suicide among U.S. college students: Implications for addressing disparities in service use. Depression and Anxiety. 2019 Jan;36(1):8-17. DOI: 10.1002/da.22830. PMID: 30188598; PMCID: PMC6628691.
https://europepmc.org/article/MED/30188598

357.  Ebert DD, Franke M, Kählke F, et al. Increasing intentions to use mental health services among university students. Results of a pilot randomized controlled trial within the World Health Organization's World Mental Health International College Student Initiative. International Journal of Methods in Psychiatric Research. 2019 Jun;28(2):e1754. DOI: 10.1002/mpr.1754. PMID: 30456814; PMCID: PMC6877244.
https://europepmc.org/article/MED/30456814

358.  González-Valero G, Zurita-Ortega F, Ubago-Jiménez JL, Puertas-Molero P. Use of Meditation and Cognitive Behavioral Therapies for the Treatment of Stress, Depression and Anxiety in Students. A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health. 2019 Nov;16(22):E4394. DOI: 10.3390/ijerph16224394. PMID: 31717682; PMCID: PMC6888319.
https://europepmc.org/article/MED/31717682

359. Davies EB, Morriss R, Glazebrook C. Computer-delivered and web-based interventions to improve depression, anxiety, and psychological well-being of university students: a systematic review and meta-analysis. J Med Internet Res. 2014 May 16;16(5):e130. doi: 10.2196/jmir.3142. PMID: 24836465; PMCID: PMC4051748.
https://pubmed.ncbi.nlm.nih.gov/24836465/

360. Matar Boumosleh J, Jaalouk D. Depression, anxiety, and smartphone addiction in university students- A cross sectional study. PLoS One. 2017 Aug 4;12(8):e0182239. doi: 10.1371/journal.pone.0182239. PMID: 28777828; PMCID: PMC5544206.
https://pubmed.ncbi.nlm.nih.gov/28777828/

361.  Latas M, Pantić M, Obradović D. [Analysis of test anxiety in medical students]. Medicinski Pregled. 2010 Nov-Dec;63(11-12):863-866. DOI: 10.2298/mpns1012863l. PMID: 21553469.
http://europepmc.org/article/MED/21553469

362.  Dikmen M. Test anxiety in online exams: scale development and validity. Current Psychology (New Brunswick, N.J.). 2022 Dec:1-13. DOI: 10.1007/s12144-022-04072-0. PMID: 36474484; PMCID: PMC9715417.
https://europepmc.org/article/MED/36474484



Φυσικά Κύτταρα-Φονείς
565. Vivier, E., Rebuffet, L., Narni-Mancinelli, E. et al. Natural killer cell therapies. Nature 626, 727–736 (2024). https://doi.org/10.1038/s41586-023-06945-1
https://www.nature.com/articles/s41586-023-06945-1

566. Freud AG, Mundy-Bosse BL, Yu J, Caligiuri MA. The Broad Spectrum of Human Natural Killer Cell Diversity. Immunity. 2017 Nov 21;47(5):820-833. doi: 10.1016/j.immuni.2017.10.008. PMID: 29166586; PMCID: PMC5728700.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5728700/

567. Mace EM. Human natural killer cells: Form, function, and development. J Allergy Clin Immunol. 2023 Feb;151(2):371-385. doi: 10.1016/j.jaci.2022.09.022. Epub 2022 Oct 1. PMID: 36195172; PMCID: PMC9905317.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9905317/

568. Chen, S., Zhu, H. & Jounaidi, Y. Comprehensive snapshots of natural killer cells functions, signaling, molecular mechanisms and clinical utilization. Sig Transduct Target Ther 9, 302 (2024). https://doi.org/10.1038/s41392-024-02005-w
https://www.nature.com/articles/s41392-024-02005-w

569. Zaharescu, I.; Moldovan, A.D.; Tanase, C. Natural Killer (NK) Cells and Their Involvement in Different Types of Cancer—Current Status of Clinical Research. J. Mind Med. Sci. 2017, 4, 31-37. https://doi.org/10.22543/7674.41.P3137
https://www.mdpi.com/2392-7674/4/1/6

570. Lodoen MB, Lanier LL. Natural killer cells as an initial defense against pathogens. Curr Opin Immunol. 2006 Aug;18(4):391-8. doi: 10.1016/j.coi.2006.05.002. Epub 2006 Jun 12. PMID: 16765573; PMCID: PMC7127478.
https://pmc.ncbi.nlm.nih.gov/articles/PMC7127478/

571. Inoue C, Takeshita T, Kondo H, Morimoto K. Cigarette smoking is associated with the reduction of lymphokine-activated killer cell and natural killer cell activities. Environ Health Prev Med. 1996 Apr;1(1):14-9. doi: 10.1007/BF02931167. PMID: 21432415.
https://pubmed.ncbi.nlm.nih.gov/21432415/

572. M. Takeuchi, S. Nagai, A. Nakajima, M. Shinya, C. Tsukano, H. Asada, K. Yoshikawa, M. Yoshimura, T. Izumi; Inhibition of Lung Natural Killer Cell Activity by Smoking: The Role of Alveolar Macrophages. Respiration 1 June 2001; 68 (3): 262–267. https://doi.org/10.1159/000050508
https://karger.com/res/article-abstract/68/3/262/288207/Inhibition-of-Lung-Natural-Killer-Cell-Activity-by?redirectedFrom=fulltext

573. Kanehisa Morimoto, Tatsuya Takeshita, Masanobu Nanno, Shinkan Tokudome, Kunio Nakayama, Modulation of natural killer cell activity by supplementation of fermented milk containing Lactobacillus casei in habitual smokers, Preventive Medicine, Volume 40, Issue 5, 2005, Pages 589-594, ISSN 0091-7435, https://doi.org/10.1016/j.ypmed.2004.07.019.
https://www.sciencedirect.com/science/article/abs/pii/S0091743504004177

574. Ferson, M., Edwards, A., Lind, A., Milton, G.W. and Hersey, P. (1979), Low natural killer-cell activity and immunoglobulin levels associated with smoking in human subjects. Int. J. Cancer, 23: 603-609. https://doi.org/10.1002/ijc.2910230504
https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.2910230504

575. Inoue, C., Takeshita, T., Kondo, H. et al. Cigarette smoking is associated with the reduction of lymphokine-activated killer cell and natural killer cell activities. Environ Health Prev Med 1, 14–19 (1996). https://doi.org/10.1007/BF02931167
https://link.springer.com/article/10.1007/BF02931167

576. Barone J, Hebert JR, Reddy MM. Dietary fat and natural-killer-cell activity. Am J Clin Nutr. 1989 Oct;50(4):861-7. doi: 10.1093/ajcn/50.4.861. PMID: 2801592.
https://pubmed.ncbi.nlm.nih.gov/2801592/

577. Giovanni Ravaglia, Paola Forti, Fabiola Maioli, Luciana Bastagli, Andrea Facchini, Erminia Mariani, Lucia Savarino, Simonetta Sassi, Domenico Cucinotta, Giorgio Lenaz, Effect of micronutrient status on natural killer cell immune function in healthy free-living subjects aged ≥90 y123, The American Journal of Clinical Nutrition, Volume 71, Issue 2, 2000, Pages 590-598, ISSN 0002-9165, https://doi.org/10.1093/ajcn/71.2.590.
https://www.sciencedirect.com/science/article/pii/S0002916523070260

578. Kim YS, Sayers TJ, Colburn NH, Milner JA, Young HA. Impact of dietary components on NK and Treg cell function for cancer prevention. Mol Carcinog. 2015 Sep;54(9):669-78. doi: 10.1002/mc.22301. Epub 2015 Apr 1. PMID: 25845339; PMCID: PMC4536099.
https://pubmed.ncbi.nlm.nih.gov/25845339/

579. Manash Pratim Pathak, Kalyani Pathak, Riya Saikia, Urvashee Gogoi, Mohammad Zaki Ahmad, Pompy Patowary, Aparoop Das, Immunomodulatory effect of mushrooms and their bioactive compounds in cancer: A comprehensive review, Biomedicine & Pharmacotherapy, Volume 149, 2022, 112901, ISSN 0753-3322, https://doi.org/10.1016/j.biopha.2022.112901.
https://www.sciencedirect.com/science/article/pii/S0753332222002906

580. Chang C-J, Chen Y-YM, Lu C-C, et al. Ganoderma lucidum stimulates NK cell cytotoxicity by inducing NKG2D/NCR activation and secretion of perforin and granulysin. Innate Immunity. 2013;20(3):301-311. doi:10.1177/1753425913491789
https://journals.sagepub.com/doi/full/10.1177/1753425913491789

581. Guggenheim AG, Wright KM, Zwickey HL. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44. PMID: 26770080; PMCID: PMC4684115.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4684115/



Αλλεργία από σημύδα
Mahmood F, Hetland G, Nentwich I, et al. <i>Agaricus blazei</i>-Based Mushroom Extract Supplementation to Birch Allergic Blood Donors: A Randomized Clinical Trial. Nutrients. 2019 Oct;11(10):E2339. DOI: 10.3390/nu11102339. PMID: 31581605; PMCID: PMC6836217.
https://europepmc.org/article/MED/31581605



Αναπνευστικό
1.Xu H, Li S. [Pharmacological effects of Bailing capsule and its application in lung disease research]. Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(20):2777-81. Chinese. PMID: 21246839.
https://pubmed.ncbi.nlm.nih.gov/21246839/

2. Jain, V., Yuan, JM. Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission: a systematic review and meta-analysis. Int J Public Health 65, 533–546 (2020). https://doi.org/10.1007/s00038-020-01390-7
https://link.springer.com/article/10.1007/s00038-020-01390-7

3. Wang NQ, Jiang LD, Zhang XM, Li ZX. [Effect of dongchong xiacao capsule on airway inflammation of asthmatic patients]. Zhongguo Zhong Yao Za Zhi. 2007 Aug;32(15):1566-8. Chinese. PMID: 17972591.
https://pubmed.ncbi.nlm.nih.gov/17972591/

4. Sun W, Yu J, Shi YM, Zhang H, Wang Y, Wu BB. [Effects of Cordyceps extract on cytokines and transcription factors in peripheral blood mononuclear cells of asthmatic children during remission stage]. Zhong Xi Yi Jie He Xue Bao. 2010 Apr;8(4):341-6. Chinese. doi: 10.3736/jcim20100407. PMID: 20388474.
https://pubmed.ncbi.nlm.nih.gov/20388474/

5. Wang N, Li J, Huang X, Chen W, Chen Y. Herbal Medicine Cordyceps sinensis Improves Health-Related Quality of Life in Moderate-to-Severe Asthma. Evid Based Complement Alternat Med. 2016;2016:6134593. doi: 10.1155/2016/6134593. Epub 2016 Dec 5. PMID: 28050193; PMCID: PMC5165155.
https://pubmed.ncbi.nlm.nih.gov/28050193/

6. Effect of Bailing capsule on the patients with stable chronic obstructive pulmonary disease / 新乡医学院学报 Xiao-Mei YUAN; Hua-Xu LI; Xin-Yuan GAO. Journal of Xinxiang Medical College ; (12): 42-44,49, 2018. Artigo em Chinês | WPRIM | ID: wpr-699467 Biblioteca responsável: WPRO
https://pesquisa.bvsalud.org/portal/resource/pt/wpr-699467

7. Sheng X, Dong Y, Cheng D, Wang N, Guo Y. Efficacy and safety of Bailing capsules in the treatment of type 2 diabetic nephropathy: a meta-analysis. Ann Palliat Med 2020;9(6):3885-3898. doi: 10.21037/apm-20-1799
https://apm.amegroups.org/article/view/56158/html

8. Xu H, Li S. [Pharmacological effects of Bailing capsule and its application in lung disease research]. Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(20):2777-81. Chinese. PMID: 21246839.
https://pubmed.ncbi.nlm.nih.gov/21246839/

9. Yu X, Mao Y, Shergis JL, et al. Effectiveness and Safety of Oral <i>Cordyceps sinensis</i> on Stable COPD of GOLD Stages 2-3: Systematic Review and Meta-Analysis. Evidence-based Complementary and Alternative Medicine : Ecam. 2019 ;2019:4903671. DOI: 10.1155/2019/4903671. PMID: 31073318; PMCID: PMC6470429.
https://europepmc.org/article/MED/31073318



Αρρυθμίες
1. Cardiovascular diseases, world health organization,
https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1

2. Kim HC. Epidemiology of cardiovascular disease and its risk factors in Korea. Glob Health Med. 2021 Jun 30;3(3):134-141. doi: 10.35772/ghm.2021.01008. PMID: 34250288; PMCID: PMC8239378.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8239378/

3. Soltani D, Azizi B, Rahimi R, Talasaz AH, Rezaeizadeh H, Vasheghani-Farahani A. Mechanism-based targeting of cardiac arrhythmias by phytochemicals and medicinal herbs: A comprehensive review of preclinical and clinical evidence. Front Cardiovasc Med. 2022 Sep 29;9:990063. doi: 10.3389/fcvm.2022.990063. PMID: 36247473; PMCID: PMC9559844.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9559844/

4. Arrhythmias What Is an Arrhythmia?, national heart lung and blood institute, Last updated on March 24, 2022
https://www.nhlbi.nih.gov/health/arrhythmias

5. Saljic A, Heijman J, Dobrev D. Recent Advances in Antiarrhythmic Drug Therapy. Drugs. 2023 Sep;83(13):1147-1160. doi: 10.1007/s40265-023-01923-3. Epub 2023 Aug 4. PMID: 37540446; PMCID: PMC10462572.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462572/

6. Pandya B, Spagnola J, Sheikh A, Karam B, Anugu VR, Khan A, Lafferty J, Kenigsberg D, Kowalski M. Anti-arrhythmic medications increase non-cardiac mortality - A meta-analysis of randomized control trials. J Arrhythm. 2016 Jun;32(3):204-11. doi: 10.1016/j.joa.2016.02.006. Epub 2016 Mar 11. PMID: 27354866; PMCID: PMC4913148.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4913148/

7. Wang L, Sun H, Yang M, Xu Y, Hou L, Yu H, Wang X, Zhang Z, Han J. Bidirectional regulatory effects of Cordyceps on arrhythmia: Clinical evaluations and network pharmacology. Front Pharmacol. 2022 Aug 19;13:948173. doi: 10.3389/fphar.2022.948173. PMID: 36059969; PMCID: PMC9437265.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9437265/

8. Yan XF, Zhang ZM, Yao HY, Guan Y, Zhu JP, Zhang LH, Jia YL, Wang RW. Cardiovascular protection and antioxidant activity of the extracts from the mycelia of Cordyceps sinensis act partially via adenosine receptors. Phytother Res. 2013 Nov;27(11):1597-604. doi: 10.1002/ptr.4899. Epub 2012 Nov 28. PMID: 23192916.
https://pubmed.ncbi.nlm.nih.gov/23192916/




Μακροζωία
1.  Borodina I, Kenny LC, McCarthy CM, et al. The biology of ergothioneine, an antioxidant nutraceutical. Nutrition Research Reviews. 2020 Dec;33(2):190-217. DOI: 10.1017/s0954422419000301. PMID: 32051057; PMCID: PMC7653990.
https://europepmc.org/article/MED/32051057

2.  Paul BD, Snyder SH. The unusual amino acid L-ergothioneine is a physiologic cytoprotectant. Cell Death and Differentiation. 2010 Jul;17(7):1134-1140. DOI: 10.1038/cdd.2009.163. PMID: 19911007; PMCID: PMC2885499.
http://europepmc.org/article/MED/19911007

3.  Ames BN. Prolonging healthy aging: Longevity vitamins and proteins. Proceedings of the National Academy of Sciences of the United States of America. 2018 Oct;115(43):10836-10844. DOI: 10.1073/pnas.1809045115. PMID: 30322941; PMCID: PMC6205492.
http://europepmc.org/article/MED/30322941

4.  Smith E, Ottosson F, Hellstrand S, et al. Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease. Heart (British Cardiac Society). 2020 May;106(9):691-697. DOI: 10.1136/heartjnl-2019-315485. PMID: 31672783; PMCID: PMC7229907.
http://europepmc.org/article/MED/31672783

5. Apparoo Y, Phan CW, Kuppusamy UR, Sabaratnam V. Ergothioneine and its prospects as an anti-ageing compound. Exp Gerontol. 2022 Dec;170:111982. doi: 10.1016/j.exger.2022.111982. Epub 2022 Oct 14. PMID: 36244584.
https://www.sciencedirect.com/science/article/pii/S0531556522002911?via%3Dihub

6. Paul BD. Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxid Redox Signal. 2022 Jun;36(16-18):1306-1317. doi: 10.1089/ars.2021.0043. Epub 2021 Dec 7. PMID: 34619979; PMCID: PMC9221166.
https://pubmed.ncbi.nlm.nih.gov/34619979/

7.  Beelman RB, Kalaras MD, Phillips AT, Richie JP Jr. Is ergothioneine a 'longevity vitamin' limited in the American diet? Journal of Nutritional Science. 2020 ;9:e52. DOI: 10.1017/jns.2020.44. PMID: 33244403; PMCID: PMC7681161.
https://europepmc.org/article/MED/33244403

8. Roda E, Ratto D, De Luca F, Desiderio A, Ramieri M, Goppa L, Savino E, Bottone MG, Locatelli CA, Rossi P. Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The "Longevity Vitamin" Improves Locomotor Performances during Aging. Nutrients. 2022 Mar 11;14(6):1177. doi: 10.3390/nu14061177. PMID: 35334834; PMCID: PMC8950371.
https://pubmed.ncbi.nlm.nih.gov/35334834/

9. Tschirka J, Kreisor M, Betz J, Gründemann D. Substrate Selectivity Check of the Ergothioneine Transporter. Drug Metab Dispos. 2018 Jun;46(6):779-785. doi: 10.1124/dmd.118.080440. Epub 2018 Mar 12. PMID: 29530864.
https://pubmed.ncbi.nlm.nih.gov/29530864/

10.  Jenny KA, Ruggles EL, Liptak MD, Masterson DS, Hondal RJ. Ergothioneine in a peptide: Substitution of histidine with 2-thiohistidine in bioactive peptides. Journal of Peptide Science : an Official Publication of the European Peptide Society. 2021 Oct;27(10):e3339. DOI: 10.1002/psc.3339. PMID: 34008255; PMCID: PMC8443123.
https://europepmc.org/article/MED/34008255

11. Stoffels C, Oumari M, Perrou A, Termath A, Schlundt W, Schmalz HG, Schäfer M, Wewer V, Metzger S, Schömig E, Gründemann D. Ergothioneine stands out from hercynine in the reaction with singlet oxygen: Resistance to glutathione and TRIS in the generation of specific products indicates high reactivity. Free Radic Biol Med. 2017 Dec;113:385-394. doi: 10.1016/j.freeradbiomed.2017.10.372. Epub 2017 Oct 23. PMID: 29074402.
https://www.sciencedirect.com/science/article/abs/pii/S0891584917311553?via%3Dihub

12.  Cheng R, Wu L, Lai R, et al. Single-step Replacement of an Unreactive C-H Bond by a C-S Bond Using Polysulfide as the Direct Sulfur Source in Anaerobic Ergothioneine Biosynthesis. ACS Catalysis. 2020 Aug;10(16):8981-8994. DOI: 10.1021/acscatal.0c01809. PMID: 34306804; PMCID: PMC8302205.
https://europepmc.org/article/MED/34306804

13. Brandalise F, Roda E, Ratto D, Goppa L, Gargano ML, Cirlincione F, Priori EC, Venuti MT, Pastorelli E, Savino E, Rossi P. Hericium erinaceus in Neurodegenerative Diseases: From Bench to Bedside and Beyond, How Far from the Shoreline? J Fungi (Basel). 2023 May 10;9(5):551. doi: 10.3390/jof9050551. PMID: 37233262; PMCID: PMC10218917.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10218917/

14. Halliwell B, Cheah I. Ergothioneine, where are we now? FEBS Lett. 2022 May;596(10):1227-1230. doi: 10.1002/1873-3468.14350. PMID: 35645151.
https://febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14350

15. Wachtel-Galor S, Tomlinson B, Benzie IF. Ganoderma lucidum ("Lingzhi"), a Chinese medicinal mushroom: biomarker responses in a controlled human supplementation study. Br J Nutr. 2004 Feb;91(2):263-9. doi: 10.1079/BJN20041039. PMID: 14756912.
https://pubmed.ncbi.nlm.nih.gov/14756912/



ατροφική γαστρίτιδα
A double-blind study of effectiveness of hericium erinaceus pers therapy on chronic atrophic gastritis. A preliminary report. Xu CP, Liu WW, Liu FX, Chen SS, Liao FQ, Xu Z, Jiang LG, Wang CA, Lu XH  Chinese Medical Journal, 01 Jun 1985, 98(6):455-456.
https://mednexus.org/doi/pdf/10.5555/cmj.0366-6999.98.06.p455.01



Γκρέιβς - Χασιμότο
1. He T, Zhao R, Lu Y, Li W, Hou X, Sun Y, Dong M, Chen L. Dual-Directional Immunomodulatory Effects of Corbrin Capsule on Autoimmune Thyroid Diseases. Evid Based Complement Alternat Med. 2016;2016:1360386. doi: 10.1155/2016/1360386. Epub 2016 Sep 18. PMID: 27721890; PMCID: PMC5045992.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045992/

2. Barić A, Brčić L, Gračan S, Škrabić V, Brekalo M, Šimunac M, Lovrić VT, Anić I, Barbalić M, Zemunik T, Punda A, Boraska Perica V. Thyroglobulin Antibodies are Associated with Symptom Burden in Patients with Hashimoto's Thyroiditis: A Cross-Sectional Study. Immunol Invest. 2019 Feb;48(2):198-209. doi: 10.1080/08820139.2018.1529040. Epub 2018 Oct 17. PMID: 30332318.
https://pubmed.ncbi.nlm.nih.gov/30332318/

3. Caturegli P, De Remigis A, Rose NR. Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmun Rev. 2014 Apr-May;13(4-5):391-7. doi: 10.1016/j.autrev.2014.01.007. Epub 2014 Jan 13. PMID: 24434360.
https://pubmed.ncbi.nlm.nih.gov/24434360/

4. Hashimoto's disease,  By Mayo Clinic Staff  Jan 15, 2022
https://www.mayoclinic.org/diseases-conditions/hashimotos-disease/symptoms-causes/syc-20351855

5. Hashimoto’s Thyroiditis (Chronic Lymphocytic Thyroiditis or Autoimmune Thyroiditis), american thyroid association
https://www.thyroid.org/hashimotos-thyroiditis/



Διαταραχές διάθεσης
Evid Based Complement Alternat Med, 2019, 7861297 2019 Apr 18 eCollection 2019 Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? Luisella Vigna, Federica Morelli, Gianna M Agnelli, Filomena Napolitano, Daniela Ratto, Alessandra Occhinegro, Carmine Di Iorio, Elena Savino, Carolina Girometta, Federico Brandalise, Paola Rossi
https://europepmc.org/article/MED/31118969



Διπολική διαταραχή
1.  Harrison PJ, Geddes JR, Tunbridge EM. The Emerging Neurobiology of Bipolar Disorder. Trends in Neurosciences. 2018 Jan;41(1):18-30. DOI: 10.1016/j.tins.2017.10.006. PMID: 29169634; PMCID: PMC5755726.
https://europepmc.org/article/MED/29169634

2. Müller JK, Leweke FM. Bipolar disorder: clinical overview. Med Monatsschr Pharm. 2016 Sep;39(9):363- 9. English, German. PMID: 29956510.
https://pubmed.ncbi.nlm.nih.gov/29956510/

3. Smith DJ, Whitham EA, Ghaemi SN. Bipolar disorder. Handb Clin Neurol. 2012;106:251-63. doi: 10.1016/B978-0-444-52002-9.00015-2. PMID: 22608626.
https://pubmed.ncbi.nlm.nih.gov/22608626/

4. What Are Bipolar Disorders?, American Psychiatric Association
https://www.psychiatry.org/patients-families/bipolar-disorders/what-are-bipolar-disorders

5. McCormick U, Murray B, McNew B. Diagnosis and treatment of patients with bipolar disorder: A review for advanced practice nurses. J Am Assoc Nurse Pract. 2015 Sep;27(9):530-42. doi: 10.1002/2327-6924.12275. Epub 2015 Jul 14. PMID: 26172568; PMCID: PMC5034840.
https://pubmed.ncbi.nlm.nih.gov/26172568/

6. Bipolar Disorder, Substance Abuse and Mental Health Services Administration,  U.S. Department of Health & Human Services
https://www.samhsa.gov/mental-health/bipolar

7. Bipolar Disorder, National Institute of Mental Health, U.S. Department of Health and Human Services.
https://www.nimh.nih.gov/health/topics/bipolar-disorder

8. Bipolar disorder, NHS of United Kingdom, 3 January 2023
https://www.nhs.uk/mental-health/conditions/bipolar-disorder/overview/

9. Suicide in bipolar disorder, July 16, 2020, The University of Texas Health Science Center at Houston (UTHealth Houston)
https://med.uth.edu/psychiatry/2020/07/16/suicide-in-bipolar-disorder/

10. Dome P, Rihmer Z, Gonda X. Suicide Risk in Bipolar Disorder: A Brief Review. Medicina (Kaunas). 2019 Jul 24;55(8):403. doi: 10.3390/medicina55080403. PMID: 31344941; PMCID: PMC6723289.
https://pubmed.ncbi.nlm.nih.gov/31344941/

11. Grande I, Berk M, Birmaher B, Vieta E. Bipolar disorder. Lancet. 2016 Apr 9;387(10027):1561-1572. doi: 10.1016/S0140-6736(15)00241-X. Epub 2015 Sep 18. PMID: 26388529.
https://pubmed.ncbi.nlm.nih.gov/26388529/

12.  Dong, M., Lu, L., Zhang, L., Zhang, Q., Ungvari, G., Ng, C., . . . Xiang, Y. (2020). Prevalence of suicide attempts in bipolar disorder: A systematic review and meta-analysis of observational studies. Epidemiology and Psychiatric Sciences, 29, E63. doi:10.1017/S2045796019000593
https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/prevalence-of-suicide-attempts-in-bipolar-disorder-a-systematic-review-and-metaanalysis-of-observational-studies/494471CA6E53CECADA92AAF9246FDC5F

13. Costa Lda S, Alencar ÁP, Nascimento Neto PJ, dos Santos Mdo S, da Silva CG, Pinheiro Sde F, Silveira RT, Bianco BA, Pinheiro RF Jr, de Lima MA, Reis AO, Rolim Neto ML. Risk factors for suicide in bipolar disorder: a systematic review. J Affect Disord. 2015 Jan 1;170:237-54. doi: 10.1016/j.jad.2014.09.003. Epub 2014 Sep 16. PMID: 25261630.
https://pubmed.ncbi.nlm.nih.gov/25261630/

14. Miller JN, Black DW. Bipolar Disorder and Suicide: a Review. Curr Psychiatry Rep. 2020 Jan 18;22(2):6. doi: 10.1007/s11920-020-1130-0. PMID: 31955273.
https://pubmed.ncbi.nlm.nih.gov/31955273/

15. Tondo L, Vázquez GH, Baldessarini RJ. Prevention of suicidal behavior in bipolar disorder. Bipolar Disord. 2021 Feb;23(1):14-23. doi: 10.1111/bdi.13017. Epub 2020 Oct 27. PMID: 33037692.
https://pubmed.ncbi.nlm.nih.gov/33037692/

16. Beyer JL, Weisler RH. Suicide Behaviors in Bipolar Disorder: A Review and Update for the Clinician. Psychiatr Clin North Am. 2016 Mar;39(1):111-23. doi: 10.1016/j.psc.2015.09.002. Epub 2015 Dec 22. PMID: 26876322.
https://pubmed.ncbi.nlm.nih.gov/26876322/

17. Bipolar Depression: The Lows We Don’t Talk About Enough,  SEP. 22, 2021  By Katherine Ponte, JD, MBA, CPRP, National Alliance on Mental Illness
https://www.nami.org/Blogs/NAMI-Blog/September-2021/Bipolar-Depression-The-Lows-We-Don-t-Talk-About-Enough

18.  Solé B, Jiménez E, Torrent C, et al. Cognitive Impairment in Bipolar Disorder: Treatment and Prevention Strategies. The International Journal of Neuropsychopharmacology. 2017 Aug;20(8):670-680. DOI: 10.1093/ijnp/pyx032. PMID: 28498954; PMCID: PMC5570032.
https://europepmc.org/article/MED/28498954

19. The Power of the Lion's Mane Mushroom: Regenerate Your Brain With Lion's Mane Edición Kindle de Ward W. Bond Ph.D. (Author), Ken Babal (Author)
https://www.amazon.com/Power-Lions-Mane-Mushroom-Regenerate-ebook/dp/B07122GLYW

20. Lai PL, Naidu M, Sabaratnam V, Wong KH, David RP, Kuppusamy UR, Abdullah N, Malek SN. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54. doi: 10.1615/intjmedmushr.v15.i6.30. PMID: 24266378.
https://pubmed.ncbi.nlm.nih.gov/24266378/

21. Zhang CC, Yin X, Cao CY, Wei J, Zhang Q, Gao JM. Chemical constituents from Hericium erinaceus and their ability to stimulate NGF-mediated neurite outgrowth on PC12 cells. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5078-82. doi: 10.1016/j.bmcl.2015.10.016. Epub 2015 Oct 16. PMID: 26481911.
https://pubmed.ncbi.nlm.nih.gov/26481911/

22. Tamrakar S, Wang D, Hiraki E, Han C, Ruan Y, Allam AE, Amen Y, Katakura Y, Shimizu K. Deacylated Derivative of Hericenone C Treated by Lipase Shows Enhanced Neuroprotective Properties Compared to Its Parent Compound. Molecules. 2023 Jun 5;28(11):4549. doi: 10.3390/molecules28114549. PMID: 37299024; PMCID: PMC10254140.
https://pubmed.ncbi.nlm.nih.gov/37299024/

23.  Rascher M, Wittstein K, Winter B, et al. Erinacine C Activates Transcription from a Consensus ETS DNA Binding Site in Astrocytic Cells in Addition to NGF Induction. Biomolecules. 2020 Oct;10(10):E1440. DOI: 10.3390/biom10101440. PMID: 33066380; PMCID: PMC7602259.
https://europepmc.org/article/MED/33066380

24.  Zhang CC, Cao CY, Kubo M, et al. Chemical Constituents from Hericium erinaceus Promote Neuronal Survival and Potentiate Neurite Outgrowth via the TrkA/Erk1/2 Pathway. International Journal of Molecular Sciences. 2017 Jul;18(8):E1659. DOI: 10.3390/ijms18081659. PMID: 28758954; PMCID: PMC5578049.
https://europepmc.org/article/PMC/5578049

25. Lee EW, Shizuki K, Hosokawa S, Suzuki M, Suganuma H, Inakuma T, Li J, Ohnishi-Kameyama M, Nagata T, Furukawa S, Kawagish H. Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum. Biosci Biotechnol Biochem. 2000 Nov;64(11):2402-5. doi: 10.1271/bbb.64.2402. PMID: 11193408.
https://pubmed.ncbi.nlm.nih.gov/11193408/

26. Mushrooms magnify memory by boosting nerve growth, 10 February 2023, The University of Queensland
https://www.uq.edu.au/news/article/2023/02/mushrooms-magnify-memory-boosting-nerve-growth-0

27. Ryu SH, Hong SM, Khan Z, Lee SK, Vishwanath M, Turk A, Yeon SW, Jo YH, Lee DH, Lee JK, Hwang BY, Jung JK, Kim SY, Lee MK. Neurotrophic isoindolinones from the fruiting bodies of Hericium erinaceus. Bioorg Med Chem Lett. 2021 Jan 1;31:127714. doi: 10.1016/j.bmcl.2020.127714. Epub 2020 Nov 25. PMID: 33246107.
https://pubmed.ncbi.nlm.nih.gov/33246107/

28.  Yin-Ching Chan, et al. "Effects of Erinacine A-enriched Hericium Erinaceus On Elderly Hearing-impaired Patients: A Double-blind, Randomized, Placebo-controlled Clinical Trial." Journal of functional foods, v. 97 ,. pp. 105220. doi: 10.1016/j.jff.2022.105220
https://pubag.nal.usda.gov/catalog/7900602

29. Sonal A, Raghavan V. Brain derived neurotrophic factor (BDNF) and suicidal behavior: A review of studies from Asian countries. Asian J Psychiatr. 2018 Mar;33:128-132. doi: 10.1016/j.ajp.2018.03.004. Epub 2018 Mar 2. PMID: 29525506.
https://www.sciencedirect.com/science/article/abs/pii/S1876201817302770

30.   L. Sher, Brain-derived neurotrophic factor and suicidal behavior, QJM: An International Journal of Medicine, Volume 104, Issue 5, May 2011, Pages 455–458, https://doi.org/10.1093/qjmed/hcq207
https://academic.oup.com/qjmed/article/104/5/455/1516419

31. Dwivedi Y. Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatr Dis Treat. 2009;5:433-49. doi: 10.2147/ndt.s5700. Epub 2009 Aug 20. PMID: 19721723; PMCID: PMC2732010.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732010/

32. Arosio B, Guerini FR, Voshaar RCO, Aprahamian I. Blood Brain-Derived Neurotrophic Factor (BDNF) and Major Depression: Do We Have a Translational Perspective? Front Behav Neurosci. 2021 Feb 12;15:626906. doi: 10.3389/fnbeh.2021.626906. PMID: 33643008; PMCID: PMC7906965.
https://www.frontiersin.org/articles/10.3389/fnbeh.2021.626906/full

33. Cristy Phillips, "Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection", Neural Plasticity, vol. 2017, Article ID 7260130, 17 pages, 2017. https://doi.org/10.1155/2017/7260130
https://www.hindawi.com/journals/np/2017/7260130/

34. Rupcic Z, Rascher M, Kanaki S, Köster RW, Stadler M, Wittstein K. Two New Cyathane Diterpenoids from Mycelial Cultures of the Medicinal Mushroom Hericium erinaceus and the Rare Species, Hericium flagellum. Int J Mol Sci. 2018 Mar 6;19(3):740. doi: 10.3390/ijms19030740. PMID: 29509661; PMCID: PMC5877601.
https://pubmed.ncbi.nlm.nih.gov/29509661/

35.  Li IC, Chang HH, Lin CH, et al. Prevention of Early Alzheimer's Disease by Erinacine A-Enriched <i>Hericium erinaceus</i> Mycelia Pilot Double-Blind Placebo-Controlled Study. Frontiers in Aging Neuroscience. 2020;12:155. DOI: 10.3389/fnagi.2020.00155. PMID: 32581767; PMCID: PMC7283924.
https://europepmc.org/article/MED/32581767

36.  Tondo L, Vázquez GH, Baldessarini RJ. Depression and Mania in Bipolar Disorder. Current Neuropharmacology. 2017 Apr;15(3):353-358. DOI: 10.2174/1570159x14666160606210811. PMID: 28503106; PMCID: PMC5405618.
https://europepmc.org/article/MED/28503106

37. Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7. doi: 10.2220/biomedres.31.231. PMID: 20834180.
https://pubmed.ncbi.nlm.nih.gov/20834180/

38. Vigna L, Morelli F, Agnelli GM, Napolitano F, Ratto D, Occhinegro A, Di Iorio C, Savino E, Girometta C, Brandalise F, Rossi P. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? Evid Based Complement Alternat Med. 2019 Apr 18;2019:7861297. doi: 10.1155/2019/7861297. PMID: 31118969; PMCID: PMC6500611.
https://pubmed.ncbi.nlm.nih.gov/31118969/

39. Ortega, M.A., Álvarez-Mon, M.A., García-Montero, C. et al. Microbiota–gut–brain axis mechanisms in the complex network of bipolar disorders: potential clinical implications and translational opportunities. Mol Psychiatry (2023). https://doi.org/10.1038/s41380-023-01964-w
https://www.nature.com/articles/s41380-023-01964-w

40.  Borkent, J., Ioannou, M., Laman, J., Haarman, B., & Sommer, I. (2022). Role of the gut microbiome in three major psychiatric disorders. Psychological Medicine, 52(7), 1222-1242. doi:10.1017/S0033291722000897
https://www.cambridge.org/core/journals/psychological-medicine/article/role-of-the-gut-microbiome-in-three-major-psychiatric-disorders/D1B42C227DBAD58750E4A44DEA041BC5

41. Guo XJ, Xiong YB, Jia Y, Cui XH, Wu WZ, Tian JS, Yang H, Ren Y. Altered Metabolomics in Bipolar Depression With Gastrointestinal Symptoms. Front Psychiatry. 2022 May 24;13:861285. doi: 10.3389/fpsyt.2022.861285. PMID: 35686183; PMCID: PMC9170992.
https://www.frontiersin.org/articles/10.3389/fpsyt.2022.861285/full

42. Stephanie A. Flowers, Kristen M. Ward, Crystal T. Clark; The Gut Microbiome in Bipolar Disorder and Pharmacotherapy Management. Neuropsychobiology 29 January 2020; 79 (1): 43–49. https://doi.org/10.1159/000504496
https://karger.com/nps/article/79/1/43/234022/The-Gut-Microbiome-in-Bipolar-Disorder-and

43. The Gut-Wrenching Problems of Mental Health  By Madeline Halpern, MHA Policy and Programs Analyst, Mental Health America
https://mhanational.org/blog/gut-wrenching-problems-mental-health

44. Generoso JS, Giridharan VV, Lee J, Macedo D, Barichello T. The role of the microbiota-gut-brain axis in neuropsychiatric disorders. Braz J Psychiatry. 2021;43:293-305. http://dx.doi.org/10.1590/1516-4446-2020-0987
https://www.scielo.br/j/rbp/a/vcVptJTbDB4M4CdscTTLGFj/?format=pdf&lang=en

45. Mitrea L, Nemeş SA, Szabo K, Teleky BE, Vodnar DC. Guts Imbalance Imbalances the Brain: A Review of Gut Microbiota Association With Neurological and Psychiatric Disorders. Front Med (Lausanne). 2022 Mar 31;9:813204. doi: 10.3389/fmed.2022.813204. PMID: 35433746; PMCID: PMC9009523.
https://pubmed.ncbi.nlm.nih.gov/35433746/

46. Harvard Health Blog Probiotics for bipolar disorder mania June 25, 2018 By Marcelo Campos, MD, Contributor
https://www.health.harvard.edu/blog/probiotics-for-bipolar-disorder-mania-2018062514125

47. Lucidi, L.; Pettorruso, M.; Vellante, F.; Di Carlo, F.; Ceci, F.; Santovito, M.C.; Di Muzio, I.; Fornaro, M.; Ventriglio, A.; Tomasetti, C.; et al. Gut Microbiota and Bipolar Disorder: An Overview on a Novel Biomarker for Diagnosis and Treatment. Int. J. Mol. Sci. 2021, 22, 3723. https://doi.org/10.3390/ijms22073723
https://www.mdpi.com/1422-0067/22/7/3723

48. He X, Wang X, Fang J, Chang Y, Ning N, Guo H, Huang L, Huang X, Zhao Z. Structures, biological activities, and industrial applications of the polysaccharides from Hericium erinaceus (Lion's Mane) mushroom: A review. Int J Biol Macromol. 2017 Apr;97:228-237. doi: 10.1016/j.ijbiomac.2017.01.040. Epub 2017 Jan 10. PMID: 28087447.
https://www.sciencedirect.com/science/article/abs/pii/S0141813016316671

49. Lee SK, Ryu SH, Turk A, Yeon SW, Jo YH, Han YK, Hwang BY, Lee KY, Lee MK. Characterization of α-glucosidase inhibitory constituents of the fruiting body of lion's mane mushroom (Hericium erinaceus). J Ethnopharmacol. 2020 Nov 15;262:113197. doi: 10.1016/j.jep.2020.113197. Epub 2020 Jul 29. PMID: 32738392.
https://pubmed.ncbi.nlm.nih.gov/32738392/

50. Chen B, Han J, Bao L, Wang W, Ma K, Liu H. Identification and α-Glucosidase Inhibitory Activity of Meroterpenoids from Hericium erinaceus. Planta Med. 2020 May;86(8):571-578. doi: 10.1055/a-1146-8369. Epub 2020 Apr 21. PMID: 32325508.
https://pubmed.ncbi.nlm.nih.gov/32325508/

51. Hericium erinaceus  Hericium erinaceus, a medicinal mushroom is known to have various health benefits and its fruiting bodies have been used in China to treat digestive system associated disorders.  From: Biological Macromolecules, 2022
https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/hericium-erinaceus

52. Shang X, Tan Q, Liu R, Yu K, Li P, Zhao GP. In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion's Mane mushroom, Hericium erinaceus (higher Basidiomycetes). Int J Med Mushrooms. 2013;15(2):165-74. doi: 10.1615/intjmedmushr.v15.i2.50. PMID: 23557368.
https://pubmed.ncbi.nlm.nih.gov/23557368/

53. Wang M, Kanako N, Zhang Y, Xiao X, Gao Q, Tetsuya K (2017) A unique polysaccharide purified from Hericium erinaceus mycelium prevents oxidative stress induced by H2O2 in human gastric mucosa epithelium cell. PLoS ONE 12(7): e0181546. https://doi.org/10.1371/journal.pone.0181546
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0181546

54. Yuan E, Nie S, Liu L, Ren J. Study on the interaction of Hericium erinaceus mycelium polysaccharides and its degradation products with food additive silica nanoparticles. Food Chem X. 2021 Nov 26;12:100172. doi: 10.1016/j.fochx.2021.100172. PMID: 34901828; PMCID: PMC8639428.
https://pubmed.ncbi.nlm.nih.gov/34901828/

55.  Miaoyu Li, et al. "Role of Dietary Edible Mushrooms In the Modulation of Gut Microbiota." Journal of functional foods, v. 83 ,. pp. 104538. doi: 10.1016/j.jff.2021.104538
https://www.sciencedirect.com/science/article/pii/S1756464621001870#s0025

56. Effects of Hericium Erinaceus on Microbiota and Cognition (HE), clinicaltrials.gov, Last Update Posted : March 1, 2023
https://classic.clinicaltrials.gov/ct2/show/study/NCT04939961

57. Jiang, Shengjuan, et al. "Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals." Applied Microbiology and Biotechnology, vol. 98, no. 18, 15 Sept. 2014, pp. 7661+. Gale OneFile: Health and Medicine, link.gale.com/apps/doc/A385260258/HRCA?u=anon~c6f7bc1&sid=googleScholar&xid=5b308856. Accessed 29 June 2023.
https://go.gale.com/ps/i.do?id=GALE%7CA385260258&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=01757598&p=HRCA&sw=w&userGroupName=anon%7Ec6f7bc1&aty=open+web+entry

58. Gravina AG, Pellegrino R, Auletta S, Palladino G, Brandimarte G, D'Onofrio R, Arboretto G, Imperio G, Ventura A, Cipullo M, Romano M, Federico A. Hericium erinaceus, a medicinal fungus with a centuries-old history: Evidence in gastrointestinal diseases. World J Gastroenterol. 2023 May 28;29(20):3048-3065. doi: 10.3748/wjg.v29.i20.3048. PMID: 37346156; PMCID: PMC10280799.
https://pubmed.ncbi.nlm.nih.gov/37346156/

59. Yang Y, Zhao C, Diao M, Zhong S, Sun M, Sun B, Ye H, Zhang T. The Prebiotic Activity of Simulated Gastric and Intestinal Digesta of Polysaccharides from the Hericium erinaceus. Molecules. 2018 Nov 30;23(12):3158. doi: 10.3390/molecules23123158. PMID: 30513668; PMCID: PMC6321054.
https://pubmed.ncbi.nlm.nih.gov/30513668/

60. Helicium erenaceus (Yamabushitake): A unique resource for developing functional foods and medicines Mingxing Wang, Yang Gao, Duoduo Xu, Tetsuya Konishi, Qipin Gao
https://pubs.rsc.org/en/content/getauthorversionpdf/C4FO00511B

61. Tian B, Geng Y, Xu T, Zou X, Mao R, Pi X, Wu W, Huang L, Yang K, Zeng X, Sun P. Digestive Characteristics of Hericium erinaceus Polysaccharides and Their Positive Effects on Fecal Microbiota of Male and Female Volunteers During in vitro Fermentation. Front Nutr. 2022 Mar 31;9:858585. doi: 10.3389/fnut.2022.858585. PMID: 35433782; PMCID: PMC9008368.
https://pubmed.ncbi.nlm.nih.gov/35433782/

62. Xie XQ, Geng Y, Guan Q, Ren Y, Guo L, Lv Q, Lu ZM, Shi JS, Xu ZH. Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study. Nutrients. 2021 Mar 21;13(3):1008. doi: 10.3390/nu13031008. PMID: 33800983; PMCID: PMC8004025.
https://pubmed.ncbi.nlm.nih.gov/33800983/

63. Kao, Li-Ting & Lin, Herng-Ching & Lee, Hsin-Chien. (2019). Inflammatory Bowel Disease and Bipolar Disorder: a Population-based Cross-sectional Study. Journal of Affective Disorders. 247. 10.1016/j.jad.2019.01.014.
https://www.researchgate.net/publication/330386507_Inflammatory_Bowel_Disease_and_Bipolar_Disorder_a_Population-based_Cross-sectional_Study

64.   Jonas F Ludvigsson and others, Association Between Inflammatory Bowel Disease and Psychiatric Morbidity and Suicide: A Swedish Nationwide Population-Based Cohort Study With Sibling Comparisons, Journal of Crohn's and Colitis, Volume 15, Issue 11, November 2021, Pages 1824–1836, https://doi.org/10.1093/ecco-jcc/jjab039
https://academic.oup.com/ecco-jcc/article/15/11/1824/6153473

65. Tavormina G. Are somatisation symptoms important evidence for an early diagnosis of bipolar spectrum mood disorders? Psychiatr Danub. 2011 Sep;23 Suppl 1:S13-4. PMID: 21894093.
https://pubmed.ncbi.nlm.nih.gov/21894093

66.   Roosmarijn C. Drexhage and others, Inflammatory gene expression in monocytes of patients with schizophrenia: overlap and difference with bipolar disorder. A study in naturalistically treated patients, International Journal of Neuropsychopharmacology, Volume 13, Issue 10, November 2010, Pages 1369–1381, https://doi.org/10.1017/S1461145710000799
https://academic.oup.com/ijnp/article/13/10/1369/658025

67.  Chou SP, Huang B, Goldstein R, Grant BF. Temporal associations between physical illnesses and mental disorders--results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Comprehensive Psychiatry. 2013 Aug;54(6):627-638. DOI: 10.1016/j.comppsych.2012.12.020. PMID: 23522830; PMCID: PMC3931424.
https://europepmc.org/article/MED/23522830

68. Maina G, Bechon E, Rigardetto S, Salvi V. General medical conditions are associated with delay to treatment in patients with bipolar disorder. Psychosomatics. 2013 Sep-Oct;54(5):437-42. doi: 10.1016/j.psym.2012.10.011. Epub 2013 Jan 22. PMID: 23352046.
https://pubmed.ncbi.nlm.nih.gov/23352046/

69. Huang H, Nissen N, Lim CT, Gören JL, Spottswood M, Huang H. Treating Bipolar Disorder in Primary Care: Diagnosis, Pharmacology, and Management. Int J Gen Med. 2022;15:8299-8314 https://doi.org/10.2147/IJGM.S386875
https://www.dovepress.com/treating-bipolar-disorder-in-primary-care-diagnosis-pharmacology-and-m-peer-reviewed-fulltext-article-IJGM

70. Hsu YC, Hsu CC, Chang KH, Lee CY, Chong LW, Wang YC, Kao CH. Increased Subsequent Risk of Peptic Ulcer Diseases in Patients With Bipolar Disorders. Medicine (Baltimore). 2015 Jul;94(29):e1203. doi: 10.1097/MD.0000000000001203. PMID: 26200637; PMCID: PMC4602988.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602988/

71. Goodwin RD, Keyes KM, Stein MB, Talley NJ. Peptic ulcer and mental disorders among adults in the community: the role of nicotine and alcohol use disorders. Psychosom Med. 2009 May;71(4):463-8. doi: 10.1097/PSY.0b013e3181988137. PMID: 19443694; PMCID: PMC3340907.
https://pubmed.ncbi.nlm.nih.gov/19443694/

72. Chen PH, Tsai SY, Pan CH, Chen YL, Chang HM, Su SS, Chen CC, Kuo CJ. Sex-specific risk profiles for suicide mortality in bipolar disorder: incidence, healthcare utilization and comorbidity. Psychol Med. 2023 Mar;53(4):1500-1509. doi: 10.1017/S003329172100307X. Epub 2021 Aug 11. PMID: 34779754.
https://pubmed.ncbi.nlm.nih.gov/34779754/

73. McIntyre RS, Konarski JZ, Soczynska JK, Wilkins K, Panjwani G, Bouffard B, Bottas A, Kennedy SH. Medical comorbidity in bipolar disorder: implications for functional outcomes and health service utilization. Psychiatr Serv. 2006 Aug;57(8):1140-4. doi: 10.1176/ps.2006.57.8.1140. PMID: 16870965.
https://pubmed.ncbi.nlm.nih.gov/16870965/

74. Liu JH, Li L, Shang XD, Zhang JL, Tan Q. Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus. J Ethnopharmacol. 2016 May 13;183:54-58. doi: 10.1016/j.jep.2015.09.004. Epub 2015 Sep 11. PMID: 26364939.
https://pubmed.ncbi.nlm.nih.gov/26364939/

75. Lu L, Li J, Cang Y. PCR-based sensitive detection of medicinal fungi Hericium species from ribosomal internal transcribed spacer (ITS) sequences. Biol Pharm Bull. 2002 Aug;25(8):975-80. doi: 10.1248/bpb.25.975. PMID: 12186429.
https://www.jstage.jst.go.jp/article/bpb/25/8/25_8_975/_pdf

76. Park, Heui-Dong & Ko, H.-G & Kim, S.H. & Park, W.-M. (2004). Molecular identification of Asian isolates of medicinal mushroom Hericium erinaceum by phylogenetic analysis of nuclear ITS rDNA. Journal of Microbiology and Biotechnology. 14. 816-821.
https://www.researchgate.net/publication/286515010_Molecular_identification_of_Asian_isolates_of_medicinal_mushroom_Hericium_erinaceum_by_phylogenetic_analysis_of_nuclear_ITS_rDNA

77. Diniz BS, Teixeira AL, Cao F, Gildengers A, Soares JC, Butters MA, Reynolds CF 3rd. History of Bipolar Disorder and the Risk of Dementia: A Systematic Review and Meta-Analysis. Am J Geriatr Psychiatry. 2017 Apr;25(4):357-362. doi: 10.1016/j.jagp.2016.11.014. Epub 2017 Jan 4. PMID: 28161155; PMCID: PMC5365367.
https://pubmed.ncbi.nlm.nih.gov/28161155/

78. Roman Meller M, Patel S, Duarte D, Kapczinski F, de Azevedo Cardoso T. Bipolar disorder and frontotemporal dementia: A systematic review. Acta Psychiatr Scand. 2021 Nov;144(5):433-447. doi: 10.1111/acps.13362. Epub 2021 Aug 25. PMID: 34390495.
https://pubmed.ncbi.nlm.nih.gov/34390495/

79. Maia da Silva MN, Porto FHG, Lopes PMG, Sodré de Castro Prado C, Frota NAF, Alves CHL, Alves GS. Frontotemporal Dementia and Late-Onset Bipolar Disorder: The Many Directions of a Busy Road. Front Psychiatry. 2021 Dec 2;12:768722. doi: 10.3389/fpsyt.2021.768722. PMID: 34925096; PMCID: PMC8674641.
https://www.frontiersin.org/articles/10.3389/fpsyt.2021.768722/full

80.  Velosa, J, Delgado, A, Finger, E, Berk, M, Kapczinski, F, de Azevedo Cardoso, T. Risk of dementia in bipolar disorder and the interplay of lithium: a systematic review and meta-analyses.
https://onlinelibrary.wiley.com/doi/abs/10.1111/acps.13153

81. Knorr, Ulla & Simonsen, Anja & Jensen, Camilla & Zetterberg, Henrik & Blennow, Kaj & Akhøj, Morten & Forman, Julie & Hasselbalch, Steen & Kessing, Lars. (2021). Alzheimer's disease related biomarkers in bipolar disorder – A longitudinal one-year case-control study. Journal of Affective Disorders. 297. 10.1016/j.jad.2021.10.074.
https://www.sciencedirect.com/science/article/abs/pii/S0165032721011587

82.  Kessing LV, Andersen PK Does the risk of developing dementia increase with the number of episodes in patients with depressive disorder and in patients with bipolar disorder? Journal of Neurology, Neurosurgery & Psychiatry 2004;75:1662-1666.
https://jnnp.bmj.com/content/75/12/1662

83. Dementia,  NeuRA Libraries
https://library.neura.edu.au/bipolar-disorder/co-occurring-conditions/physical-disorders-co-occurring-conditions/dementia-2/index.html

84. Terao T, Ishii N, Hirakawa H. A specific group of patients with diagnostic conversion from depression to bipolar disorder and finally to dementia as a mental GSK-3 disease: A hypothesis. Bipolar Disord. 2020 Jun;22(4):356-359. doi: 10.1111/bdi.12875. Epub 2020 Jan 5. PMID: 31742842.
https://pubmed.ncbi.nlm.nih.gov/31742842/

85. Möller HJ. Bipolar disorder and schizophrenia: distinct illnesses or a continuum? J Clin Psychiatry. 2003;64 Suppl 6:23-7; discussion 28. PMID: 12720477.
https://pubmed.ncbi.nlm.nih.gov/12720477/

86. Maier W, Zobel A, Wagner M. Schizophrenia and bipolar disorder: differences and overlaps. Curr Opin Psychiatry. 2006 Mar;19(2):165-70. doi: 10.1097/01.yco.0000214342.52249.82. PMID: 16612197.
https://pubmed.ncbi.nlm.nih.gov/16612197

87. Walker J, Curtis V, Murray RM. Schizophrenia and bipolar disorder: similarities in pathogenic mechanisms but differences in neurodevelopment. Int Clin Psychopharmacol. 2002 Aug;17 Suppl 3:S11-9. PMID: 12570067.
https://pubmed.ncbi.nlm.nih.gov/12570067/

88. Yamada Y, Matsumoto M, Iijima K, Sumiyoshi T. Specificity and Continuity of Schizophrenia and Bipolar Disorder: Relation to Biomarkers. Curr Pharm Des. 2020;26(2):191-200. doi: 10.2174/1381612825666191216153508. PMID: 31840595; PMCID: PMC7403693.
https://pubmed.ncbi.nlm.nih.gov/31840595/

89.  Borkent, J., Ioannou, M., Laman, J., Haarman, B., & Sommer, I. (2022). Role of the gut microbiome in three major psychiatric disorders. Psychological Medicine, 52(7), 1222-1242. doi:10.1017/S0033291722000897
https://www.cambridge.org/core/journals/psychological-medicine/article/role-of-the-gut-microbiome-in-three-major-psychiatric-disorders/D1B42C227DBAD58750E4A44DEA041BC5

90. New research suggests gut microbiome plays a role in bipolar disorder by Eric W. Dolan May 15, 2017 in Mental Health, PsyPost
https://www.psypost.org/2017/05/new-research-suggests-gut-microbiome-plays-role-bipolar-disorder-48953

91. Cantarero-Prieto D, Moreno-Mencia P. The effects of gastrointestinal disturbances on the onset of depression and anxiety. PLoS One. 2022 Jan 25;17(1):e0262712. doi: 10.1371/journal.pone.0262712. PMID: 35077463; PMCID: PMC8789191.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262712

92. Evans SJ, Bassis CM, Hein R, Assari S, Flowers SA, Kelly MB, Young VB, Ellingrod VE, McInnis MG. The gut microbiome composition associates with bipolar disorder and illness severity. J Psychiatr Res. 2017 Apr;87:23-29. doi: 10.1016/j.jpsychires.2016.12.007. Epub 2016 Dec 10. PMID: 27988330; PMCID: PMC5336480.
https://www.sciencedirect.com/science/article/abs/pii/S0022395616307725

93. Saccaro LF, Schilliger Z, Dayer A, Perroud N, Piguet C. Inflammation, anxiety, and stress in bipolar disorder and borderline personality disorder: A narrative review. Neurosci Biobehav Rev. 2021 Aug;127:184-192. doi: 10.1016/j.neubiorev.2021.04.017. Epub 2021 Apr 27. PMID: 33930472.
https://pubmed.ncbi.nlm.nih.gov/33930472/

94. Couillard Larocque M, Fortin-Vidah G, Angers M, Garceau L, Gros L, Fournel I, Provencher MD. Anxiety in bipolar disorder: A review of publication trends. J Affect Disord. 2023 Jan 1;320:340-347. doi: 10.1016/j.jad.2022.09.057. Epub 2022 Sep 27. PMID: 36174785.
https://www.sciencedirect.com/science/article/abs/pii/S0165032722010618

95. Marley S (2022) Bipolar Disorder and it�¢??s Effects on the Various Body Systems. Bipolar Disord 8: 181. doi:10.35248/2472-1077.22.8.181
https://www.longdom.org/open-access/bipolar-disorder-and-its-effects-on-the-various-body-systems-82125.html

96. Cullen C, Kappelmann N, Umer M, Abdolizadeh A, Husain MO, Bonato S, Sharma G, Xue S, Ortiz A, Kloiber SM, Mulsant BH, Husain MI. Efficacy and acceptability of pharmacotherapy for comorbid anxiety symptoms in bipolar disorder: A systematic review and meta-analysis. Bipolar Disord. 2021 Dec;23(8):754-766. doi: 10.1111/bdi.13125. Epub 2021 Sep 15. PMID: 34506075.
https://pubmed.ncbi.nlm.nih.gov/34506075/

97. Kauer-Sant'Anna M, Kapczinski F, Vieta E. Epidemiology and management of anxiety in patients with bipolar disorder. CNS Drugs. 2009 Nov;23(11):953-64. doi: 10.2165/11310850-000000000-00000. PMID: 19845416.
https://pubmed.ncbi.nlm.nih.gov/19845416/

98. Seeberg I, Nielsen IB, Jørgensen CK, Eskestad ND, Miskowiak KW. Effects of psychological and pharmacological interventions on anxiety symptoms in patients with bipolar disorder in full or partial remission: A systematic review. J Affect Disord. 2021 Jan 15;279:31-45. doi: 10.1016/j.jad.2020.09.119. Epub 2020 Oct 1. PMID: 33038698.
https://pubmed.ncbi.nlm.nih.gov/33038698/

99. Bipolar and Anxiety Disorders, University of Miami Health Systems
https://umiamihealth.org/treatments-and-services/psychiatry/bipolar-and-anxiety-disorders

100. Corry, J., Green, M., Roberts, G. et al. Does perfectionism in bipolar disorder pedigrees mediate associations between anxiety/stress and mood symptoms?. Int J Bipolar Disord 5, 34 (2017). https://doi.org/10.1186/s40345-017-0102-8
https://journalbipolardisorders.springeropen.com/articles/10.1186/s40345-017-0102-8

101. Ott CA. Treatment of anxiety disorders in patients with comorbid bipolar disorder. Ment Health Clin. 2018 Nov 1;8(6):256-263. doi: 10.9740/mhc.2018.11.256. PMID: 30397567; PMCID: PMC6213896.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6213896/

102. Daud S (2021) A Short Note on Anxiety Types Linked with Bipolar Disorder. Bipolar Disord 7: 146. doi:10.35248/2472-1077.21.7.146
https://www.longdom.org/open-access/a-short-note-on-anxiety-types-linked-with-bipolar-disorder-76913.html

103. Jensen RN, Csillag C, Vinberg M. [Anxiety in patients with bipolar affective disorder]. Ugeskr Laeger. 2021 May 31;183(22):V12200973. Danish. PMID: 34060453.
https://pubmed.ncbi.nlm.nih.gov/34060453/

Ελικοβακτηρίδιο
1. Zamani M, Ebrahimtabar F, Zamani V, Miller WH, Alizadeh-Navaei R, Shokri-Shirvani J, Derakhshan MH. Systematic review with meta-analysis: the worldwide prevalence of Helicobacter pylori infection. Aliment Pharmacol Ther. 2018 Apr;47(7):868-876. doi: 10.1111/apt.14561. Epub 2018 Feb 12. PMID: 29430669.
https://pubmed.ncbi.nlm.nih.gov/29430669/

2. Ayala G, Escobedo-Hinojosa WI, Cruz-Herrera CFL, Romero I. Exploring alternative treatments for Helicobacter pylori infection. World J Gastroenterol 2014; 20(6): 1450-1469 [PMID: 24587621 DOI: 10.3748/wjg.v20.i6.1450]
https://www.wjgnet.com/1007-9327/full/v20/i6/1450.htm

3. Kamboj AK, Cotter TG, Oxentenko AS. Helicobacter pylori: The Past, Present, and Future in Management. Mayo Clin Proc. 2017 Apr;92(4):599-604. doi: 10.1016/j.mayocp.2016.11.017. Epub 2017 Feb 13. PMID: 28209367.
https://pubmed.ncbi.nlm.nih.gov/28209367/

4. Guo C, Liao Y, Li Y, Duan J, Guo Y, Wu Y, Cui Y, Sun H, Zhang J, Chen B, Zou Q, Guo G. Genotyping analysis of Helicobacter pylori using multiple-locus variable-number tandem-repeats analysis in five regions of China and Japan. BMC Microbiol. 2011 Sep 3;11:197. doi: 10.1186/1471-2180-11-197. PMID: 21888662; PMCID: PMC3178492.
https://pubmed.ncbi.nlm.nih.gov/21888662/

5. Camilo V, Sugiyama T, Touati E. Pathogenesis of Helicobacter pylori infection. Helicobacter. 2017 Sep;22 Suppl 1. doi: 10.1111/hel.12405. PMID: 28891130.
https://pubmed.ncbi.nlm.nih.gov/28891130/

6. Liu Q, Meng X, Li Y, Zhao CN, Tang GY, Li S, Gan RY, Li HB. Natural Products for the Prevention and Management of Helicobacter pylori Infection. Compr Rev Food Sci Food Saf. 2018 Jul;17(4):937-952. doi: 10.1111/1541-4337.12355. Epub 2018 Jun 15. PMID: 33350111.
https://pubmed.ncbi.nlm.nih.gov/33350111/

7. Yu M, Zhang R, Ni P, Chen S, Duan G. Helicobacter pylori Infection and Psoriasis: A Systematic Review and Meta-Analysis. Medicina (Kaunas). 2019 Sep 26;55(10):645. doi: 10.3390/medicina55100645. PMID: 31561576; PMCID: PMC6843633.
https://pubmed.ncbi.nlm.nih.gov/31561576/

8. Gravina AG, Zagari RM, De Musis C, Romano L, Loguercio C, Romano M. Helicobacter pylori and extragastric diseases: A review. World J Gastroenterol. 2018 Aug 7;24(29):3204-3221. doi: 10.3748/wjg.v24.i29.3204. PMID: 30090002; PMCID: PMC6079286.
https://pubmed.ncbi.nlm.nih.gov/30090002/

9. Liu, Jian-Hui & Li, Liang & Shang, Xiao-Dong & Zhang, Jun-Ling & Tan, Qi. (2015). Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus. Journal of ethnopharmacology. 183. 10.1016/j.jep.2015.09.004.
https://www.researchgate.net/publication/281852607_Anti-Helicobacter_pylori_activity_of_bioactive_components_isolated_from_Hericium_erinaceus

10. Luong, Ngan & VI, Nguyen & Doan, Tham & Loan, Le & Ho, Thanh & Tran, Trung Hieu. (2021). Antioxidant and anti-Helicobacter pylori activities of Hericium erinaceus mycelium and culture filtrate. Biomedical Research and Therapy. 8. 4266-4275. 10.15419/bmrat.v8i3.665.
https://www.researchgate.net/publication/350713224_Antioxidant_and_anti-Helicobacter_pylori_activities_of_Hericium_erinaceus_mycelium_and_culture_filtrate

11. Savoldi A, Carrara E, Graham DY, Conti M, Tacconelli E. Prevalence of Antibiotic Resistance in Helicobacter pylori: A Systematic Review and Meta-analysis in World Health Organization Regions. Gastroenterology. 2018 Nov;155(5):1372-1382.e17. doi: 10.1053/j.gastro.2018.07.007. Epub 2018 Jul 7. PMID: 29990487; PMCID: PMC6905086.
https://pubmed.ncbi.nlm.nih.gov/29990487/

12. Moghadam MT, Chegini Z, Khoshbayan A, Farahani I, Shariati A. Helicobacter pylori Biofilm and New Strategies to Combat it. Curr Mol Med. 2021;21(7):549-561. doi: 10.2174/1566524020666201203165649. PMID: 33272177.
https://pubmed.ncbi.nlm.nih.gov/33272177/

13. Saxena A, Mukhopadhyay AK, Nandi SP. Helicobacter pylori: Perturbation and restoration of gut microbiome. J Biosci. 2020;45(1):110. doi: 10.1007/s12038-020-00078-7. PMID: 32975237; PMCID: PMC7481552.
https://pubmed.ncbi.nlm.nih.gov/32975237/

14. In Vitro and in Vivo Antimicrobial Effects of Aloe Vera Fermented Hericium Erinaceum KU-1 for Food Borne Pathogens and Helicobacter Pylori Dong Myong Kim, Ju Yeong Jung, Hyung Kon Lee, Yong Seong Kwon, Yeon Mea Choi, Hyo Kyu Lee, Youn Hee Nam, Tong Ho Kang. January 13, 2022
https://biomedres.us/fulltexts/BJSTR.MS.ID.006544.php

15. Jing-Yang Wong, Mahmood Ameen Abdulla, Jegadeesh Raman, Chia-Wei Phan, Umah Rani Kuppusamy, Shahram Golbabapour, Vikineswary Sabaratnam, "Gastroprotective Effects of Lion’s Mane Mushroom Hericium erinaceus (Bull.:Fr.) Pers. (Aphyllophoromycetideae) Extract against Ethanol-Induced Ulcer in Rats", Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 492976, 9 pages, 2013. https://doi.org/10.1155/2013/492976
https://www.hindawi.com/journals/ecam/2013/492976/

16. Zhu Y, Chen Y, Li Q, Zhao T, Zhang M, Feng W, Takase M, Wu X, Zhou Z, Yang L, Wu X. Preparation, characterization, and anti-Helicobacter pylori activity of Bi3+-Hericium erinaceus polysaccharide complex. Carbohydr Polym. 2014 Sep 22;110:231-7. doi: 10.1016/j.carbpol.2014.03.081. Epub 2014 Apr 2. PMID: 24906751.
https://pubmed.ncbi.nlm.nih.gov/24906751/

17. Wang G, Zhang X, Maier SE, Zhang L, Maier RJ. In Vitro and In Vivo Inhibition of Helicobacter pylori by Ethanolic Extracts of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). Int J Med Mushrooms. 2019;21(1):1-11. doi: 10.1615/IntJMedMushrooms.2018029487. PMID: 30806251.
https://pubmed.ncbi.nlm.nih.gov/30806251/

18. Shang X, Tan Q, Liu R, Yu K, Li P, Zhao GP. In vitro anti-Helicobacter pylori effects of medicinal mushroom extracts, with special emphasis on the Lion's Mane mushroom, Hericium erinaceus (higher Basidiomycetes). Int J Med Mushrooms. 2013;15(2):165-74. doi: 10.1615/intjmedmushr.v15.i2.50. PMID: 23557368.
https://pubmed.ncbi.nlm.nih.gov/23557368/

19. Liu JH, Li L, Shang XD, Zhang JL, Tan Q. Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus. J Ethnopharmacol. 2016 May 13;183:54-58. doi: 10.1016/j.jep.2015.09.004. Epub 2015 Sep 11. PMID: 26364939.
https://pubmed.ncbi.nlm.nih.gov/26364939/

20. Donatini, B. Étude randomisée comparant l’efficacité d’Hericium erinaceus versus huiles essentielles sur Helicobacter pylori (HP). Phytothérapie 12, 3–5 (2014). https://doi.org/10.1007/s10298-014-0831-5 (Randomized study comparing the efficacy of Hericium versus essential oils against Helicobacter pylori (HP) infection)
https://link.springer.com/article/10.1007/s10298-014-0831-5

21. Buzás GM. Quality of life in patients with functional dyspepsia: Short- and long-term effect of Helicobacter pylori eradication with pantoprazole, amoxicillin, and clarithromycin or cisapride therapy: A prospective, parallel-group study. Curr Ther Res Clin Exp. 2006 Sep;67(5):305-20. doi: 10.1016/j.curtheres.2006.11.001. PMID: 24678104; PMCID: PMC3966001.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966001/

22. Bilge Gültepe, Hülya Günbatar, Ahmet Cumhur Dülger. Helicobacter pylori seroprevalance in patients with obstructive sleep apnea syndrome. . 2014; 19(1): 13-15
https://dergipark.org.tr/en/download/article-file/62157

23. Yildirim, Oguzhan & Bali, Ilhan & Tulubas, Feti & Mete, Rafet & Topçu, Birol & Seckin, Yuksel & Cagin, Yasir & Bilgic, Yilmaz & Alp, Recep. (2016). Association of CagA-positive Helicobacter pylori infection with severity of obstructive sleep apnea syndrome. Biomedical Research. 27. 867-871.
https://www.alliedacademies.org/abstract/association-of-cagapositive-helicobacter-pylori-infection-with-severity-of-obstructive-sleep-apnea-syndrome-4529.html

24. Liu, Min & Luo, Cai-Feng. (2019). Correlation Analysis of Mental Health Status and Sleep Quality in Helicobacter pylori Positive Patients. Journal of Medical Imaging and Health Informatics. 9. 1600-1606. 10.1166/jmihi.2019.2768.
https://www.researchgate.net/publication/336185402_Correlation_Analysis_of_Mental_Health_Status_and_Sleep_Quality_in_Helicobacter_pylori_Positive_Patients
https://jcmp.yzu.edu.cn/en/article/doi/10.7619/jcmp.201911008

25. Sung YF, Yin JH, Lee KH, Tsai CL, Lin YK, Chen SY, Chung CH, Chien WC, Lee JT, Chou CH. Increased risk of sleep-related movement disorder in patients with Helicobacter pylori infection: A nationwide population-based study. Front Neurol. 2022 Oct 10;13:953821. doi: 10.3389/fneur.2022.953821. PMID: 36299273; PMCID: PMC9589275.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589275/

26. Sung YF, Yin JH, Lee KH, Tsai CL, Lin YK, Chen SY, Chung CH, Chien WC, Lee JT, Chou CH. Increased risk of sleep-related movement disorder in patients with Helicobacter pylori infection: A nationwide population-based study. Front Neurol. 2022 Oct 10;13:953821. doi: 10.3389/fneur.2022.953821. PMID: 36299273; PMCID: PMC9589275.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9589275/

27. Wei BR, Zhao YJ, Cheng YF, Huang C, Zhang F. Helicobacter pylori infection and Parkinson's Disease: etiology, pathogenesis and levodopa bioavailability. Immun Ageing. 2024 Jan 2;21(1):1. doi: 10.1186/s12979-023-00404-1. PMID: 38166953; PMCID: PMC10759355.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10759355/

28. Kamarehei F, Mohammadi Y. The Effect of Helicobacter pylori Infection on Overweight: A Systematic Review and Meta-Analysis. Iran J Public Health. 2022 Nov;51(11):2417-2424. doi: 10.18502/ijph.v51i11.11159. PMID: 36561269; PMCID: PMC9745394.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745394/

29. Baradaran, A., Dehghanbanadaki, H., Naderpour, S. et al. The association between Helicobacter pylori and obesity: a systematic review and meta-analysis of case–control studies. Clin Diabetes Endocrinol 7, 15 (2021). https://doi.org/10.1186/s40842-021-00131-w
https://clindiabetesendo.biomedcentral.com/articles/10.1186/s40842-021-00131-w

30. What to Know About H. Pylori, the Pathogen That Causes the Most Cancer Cases Worldwide By Elizabeth Yuko, PhD Published on September 25, 2024, Health
https://www.health.com/this-bacteria-causes-more-cancer-cases-than-all-other-pathogens-8717406



Έμφραγμα μυοκαρδίου
Djanggan Sargowo, Evita Febriyanti Purwanto, Fariz Wahyu Nugroho, Putri Annisa Kamila, Dedy Irawan, Monika Sitio, Liemena Harold Adrian, Aditya Reza Pratama, Yusuf Arifin, M. Rizki Fadlan, Diah Ivana Sari, Firyal Nadiah Rahmah, Chamelia Rohadatul Aissy, Nurul Aini Rahmawati, Rakhmawati Fahmiy, and Merkuri Puspasari Sukatman , "The role of polysaccharide peptides of miselia Ganoderma lucidum extracts on IL-1, IL-6, HSCRP and no in dislipidemic patients with or without hypertension in STEMI and NSTEMI patients", AIP Conference Proceedings 2108, 020027 (2019) https://doi.org/10.1063/1.5110002
https://aip.scitation.org/doi/10.1063/1.5110002



Ψυχοσωματική Ευεξία
Mitra S, Mitra M, Nandi DK, Saha M, Bandyopadhyay A. Efficacy of Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Supplementation on Psychological Stress and Selective Fitness Profile Parameters in Female College Students in West Bengal, India. Int J Med Mushrooms. 2024;26(11):51-64. doi: 10.1615/IntJMedMushrooms.2024055300. PMID: 39241163.
https://pubmed.ncbi.nlm.nih.gov/39241163/



Κίρρωση
1. Zhu JS, Halpern GM, Jones K. The scientific rediscovery of a precious ancient Chinese herbal regimen: Cordyceps sinensis: part II. J Altern Complement Med. 1998 Winter;4(4):429-57. doi: 10.1089/acm.1998.4.429. PMID: 9884180.
https://pubmed.ncbi.nlm.nih.gov/9884180/

2. Gong HY, Wang KQ, Tang SG. [Effects of cordyceps sinensis on T lymphocyte subsets and hepatofibrosis in patients with chronic hepatitis B]. Hunan Yi Ke Da Xue Xue Bao. 2000 Jun 28;25(3):248-50. Chinese. PMID: 12212155.
https://pubmed.ncbi.nlm.nih.gov/12212155/

3. Wang XB, Jiang YY, Zhao CY. [Clinical research of xinganbao capsule on the treatment of chronic hepatitis B liver fibrosis]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2012 Mar;32(3):325-8. Chinese. PMID: 22686076.
https://pubmed.ncbi.nlm.nih.gov/22686076/

4. Zhang HX, Cheng CX, Yi JH. [Therapeutic effect of capsule xinganbao on schistosomal hepatocirrhosis]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2011 Jun;23(3):284, 291. Chinese. PMID: 22164492.
https://pubmed.ncbi.nlm.nih.gov/22164492/
"Xinganbao" είναι μία άλλη ονομασία για το Κόρντισεπς σίνενσις, όπως επιβεβαιώνεται και εδώ.

5. Wu W, Feng A, Huang Y. Research and control of advanced schistosomiasis japonica in China. Parasitol Res. 2015 Jan;114(1):17-27. doi: 10.1007/s00436-014-4225-x. Epub 2014 Nov 19. PMID: 25403379.
https://pubmed.ncbi.nlm.nih.gov/25403379/



Ινομυαλγία
1. Wolfe F, Smythe HA, Yunus MB, et al. The american-colle- ge-of-rheumatology 1990 criteria for the classification of fi – bromyalgia – report of the multicenter criteria committee. Ar – thritis and rheumatism 1990; 33(2): 160-72.

2. Bennett RM, Jones J, Turk DC, Russell IJ, Matallana L. An internet survey of 2,596 people with fibromyalgia. Bmc Mus- culoskeletal Disorders 2007; 8.

3. Wilson HD, Robinson JP, Turk DC. Toward the Identification of Symptom Patterns in People With Fibromyalgia. Arthritis & Rheumatism-Arthritis Care & Research 2009; 61(4): 527-34.

4. Branco JC, Bannwarth B, Failde I, et al. Prevalence of Fibrom- yalgia: A Survey in Five European Countries. Seminars in ar – thritis and rheumatism 2010; 39(6): 448-53

5. Segura-Jimenez V, Aparicio VA, Alvarez-Gallardo IC, Car – bonell-Baeza A, Tornero-Quinones I, Delgado-Fernandez M. Does body composition differ between fibromyalgia patients and controls? The al-Andalus project. Clinical and experimen- tal rheumatology 2015; 33(1 Suppl 88): 25-32.

6. Rusu C, Gee ME, Lagace C, Parlor M. Chronic fatigue syndro- me and fibromyalgia in Canada: prevalence and associations with six health status indicators. Health promotion and chronic disease prevention in Canada 2015; 35(1): 3-11.

7. Everson-Hock ES, Green MA, Goyder EC, et al. Reducing the impact of physical inactivity: evidence to support the case for targeting people with chronic mental and physical conditions. Journal of public health 2015.

8. Gusi N, Tomas-Carus P, Hakkinen A, Hakkinen K, Orte- ga-Alons A. Exercise in waist-high warm water decreases pain and improves health-related quality of life and strength in the lower extremities in women with fibromyalgia. Arthritis & Rheumatism-Arthritis Care & Research 2006; 55(1): 66-73.

9. Busch AJ, Schachter CL, Overend TJ, Peloso PM, Barber KAR. Exercise for fibromyalgia: A systematic review. Journal of Rheumatology 2008; 35(6): 1130-44.

10. Shaver JL, Wilbur J, Lee H, Robinson FP, Wang E. Self-Re- ported Medication and Herb/Supplement Use by Women with and without Fibromyalgia. Journal of Womens Health 2009; 18(5): 709-16.

11. Batra P, Sharma AK, Khajuria R. Probing Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Higher Basi- diomycetes): A Bitter Mushroom with Amazing Health Be- nefits. International journal of medicinal mushrooms 2013; 15(2): 127-43.

12. Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X. Chemical characterization and antitumor activities of polysaccharide extracted from Ganoderma lucidum. International journal of molecular sciences 2014; 15(5): 9103-16.

13. Pan D, Zhang D, Wu J, et al. Antidiabetic, antihyperlipidemic and antioxidant activities of a novel proteoglycan from gano- derma lucidum fruiting bodies on db/db mice and the possible mechanism. PloS one 2013; 8(7): e68332.

14. Li Y, Yang Y, Fang L, Zhang Z, Jin J, Zhang K. Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine. The American journal of Chi – nese medicine 2006; 34(2): 341-9.

15. Yoon HM, Jang KJ, Han MS, et al. Ganoderma lucidum etha- nol extract inhibits the inflammatory response by suppressing the NF-kappaB and toll-like receptor pathways in lipopolysac- charide-stimulated BV2 microglial cells. Experimental and therapeutic medicine 2013; 5(3): 957-63.

16. Zhang W, Tao J, Yang X, et al. Antiviral effects of two Gano- derma lucidum triterpenoids against enterovirus 71 infection. Biochemical and biophysical research communications 2014; 449(3): 307-12.

17. Zhang W, Zhang Q, Deng W, et al. Neuroprotective effect of pretreatment with ganoderma lucidum in cerebral ischemia/ reperfusion injury in rat hippocampus. Neural regeneration research 2014; 9(15): 1446-52.

18. Tran HB, Yamamoto A, Matsumoto S, et al. Hypotensive effects and angiotensin-converting enzyme inhibitory peptides of reishi (Ganoderma lingzhi) auto-digested extract. Molecules 2014; 19(9): 13473-85.

19. Rossi P, Buonocore D, Altobelli E, et al. Improving Training Condition Assessment in Endurance Cyclists: Effects of Gano- derma lucidum and Ophiocordyceps sinensis Dietary Supple – mentation. Evidence-based complementary and alternative medicine : eCAM 2014; 2014: 979613.

20. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fati – gue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evidence-based complementary and al- ternative medicine : eCAM 2012; 2012: 809614.

21. El Hajaji H, Lachkar N, Alaoui K, et al. Antioxidant activity, phytochemical screening, and total phenolic content of extracts from three genders of carob tree barks growing in Morocco. Arabian Journal of Chemistry 2011; 4(3): 321-4.

22. Yousif AK, Alghzawi HM. Processing and characterization of carob powder. Food chemistry 2000; 69(3): 283-7

23. Rossi A, Di Lollo AC, Guzzo MP, et al. Fibromyalgia and nu- trition: what news? Clinical and experimental rheumatology 2015; 33(1 Suppl 88): S117-25.

24. Motyl JM, Driban JB, McAdams E, Price LL, McAlindon TE. Test-retest reliability and sensitivity of the 20-meter walk test among patients with knee osteoarthritis. BMC musculoskeletal disorders 2013; 14: 166.

25. Juuso P, Skar L, Olsson M, Soderberg S. Meanings of feeling well for women with fibromyalgia. Health care for women in- ternational 2013; 34(8): 694-706.

26. Nutr Hosp. 2015 Nov 1;32(5):2126-35. doi: 10.3305/nh.2015.32.5.9601. GANODERMA LUCIDUM IMPROVES PHYSICAL FITNESS IN WOMEN WITH FIBROMYALGIA. Collado Mateo D1, Pazzi F2, Domínguez Muñoz FJ3, Martín Martínez JP4, Olivares PR5, Gusi N6, Adsuar JC4

27.Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum Effects on Mood and Health-Related Quality of Life in Women with Fibromyalgia. Healthcare (Basel). 2020 Nov 30;8(4):520. doi: 10.3390/healthcare8040520. PMID: 33265969; PMCID: PMC7712001.



Ινομυώματα
1. Taylor DK, Leppert PC. Treatment for Uterine Fibroids: Searching for Effective Drug Therapies. Drug Discov Today Ther Strateg. 2012;9(1):e41-e49. doi: 10.1016/j.ddstr.2012.06.001. PMID: 23264802; PMCID: PMC3525705.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525705/

2. Zhao S, Ye G, Fu G, Cheng J, Yang BB and Peng C: Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin. Int J Oncol 38: 1319-1327, 2011
https://www.spandidos-publications.com/ijo/38/5/1319

3. Geng X, Zhong D, Su L, Lin Z, Yang B. Preventive and therapeutic effect of Ganoderma lucidum on kidney injuries and diseases. Adv Pharmacol. 2020;87:257-276. doi: 10.1016/bs.apha.2019.10.003. Epub 2019 Nov 20. PMID: 32089235.
https://pubmed.ncbi.nlm.nih.gov/32089235/

4. Guo C, Guo D, Fang L, Sang T, Wu J, Guo C, Wang Y, Wang Y, Chen C, Chen J, Chen R, Wang X. Ganoderma lucidum polysaccharide modulates gut microbiota and immune cell function to inhibit inflammation and tumorigenesis in colon. Carbohydr Polym. 2021 Sep 1;267:118231. doi: 10.1016/j.carbpol.2021.118231. Epub 2021 May 20. PMID: 34119183.
https://pubmed.ncbi.nlm.nih.gov/34119183/

5. Kabodmehri R, Etezadi A, Sharami SH, Ghanaei MM, Hosseinzadeh F, Heirati SFD, Pourhabibi Z. The association between chronic endometritis and uterine fibroids. J Family Med Prim Care. 2022 Feb;11(2):653-659. doi: 10.4103/jfmpc.jfmpc_1470_21. Epub 2022 Feb 16. PMID: 35360819; PMCID: PMC8963633.
https://pubmed.ncbi.nlm.nih.gov/35360819/

6. Elkafas H, Badary O, Elmorsy E, Kamel R, Yang Q, Al-Hendy A. Endocrine-Disrupting Chemicals and Vitamin D Deficiency in the Pathogenesis of Uterine Fibroids. J Adv Pharm Res. 2021 Spring;5(2):260-275. doi: 10.21608/aprh.2021.66748.1124. PMID: 34746367; PMCID: PMC8570385.
https://pubmed.ncbi.nlm.nih.gov/34746367/

7. Pavone D, Clemenza S, Sorbi F, Fambrini M, Petraglia F. Epidemiology and Risk Factors of Uterine Fibroids. Best Pract Res Clin Obstet Gynaecol. 2018 Jan;46:3-11. doi: 10.1016/j.bpobgyn.2017.09.004. Epub 2017 Oct 1. PMID: 29054502.
https://pubmed.ncbi.nlm.nih.gov/29054502/

8.  Lethaby A, Vollenhoven B. Fibroids (uterine myomatosis, leiomyomas). BMJ Clinical Evidence. 2015 Jun;2015:0814. PMID: 26032466; PMCID: PMC4451527.
https://europepmc.org/article/MED/26032466

9.  Wise LA, Laughlin-Tommaso SK. Epidemiology of Uterine Fibroids: From Menarche to Menopause. Clinical Obstetrics and Gynecology. 2016 Mar;59(1):2-24. DOI: 10.1097/grf.0000000000000164. PMID: 26744813; PMCID: PMC4733579.
https://europepmc.org/article/MED/26744813

10.  Venkatesh SS, Ferreira T, Benonisdottir S, et al. Obesity and risk of female reproductive conditions: A Mendelian randomisation study. Plos Medicine. 2022 Feb;19(2):e1003679. DOI: 10.1371/journal.pmed.1003679. PMID: 35104295; PMCID: PMC8806071.
https://europepmc.org/article/MED/35104295

11. Expert Panel on GYN and OB Imaging; Ascher SM, Wasnik AP, Robbins JB, Adelman M, Brook OR, Feldman MK, Jones LP, Knavel Koepsel EM, Patel-Lippmann KK, Patlas MN, VanBuren W, Maturen KE. ACR Appropriateness Criteria® Fibroids. J Am Coll Radiol. 2022 Nov;19(11S):S319-S328. doi: 10.1016/j.jacr.2022.09.019. PMID: 36436959.
https://pubmed.ncbi.nlm.nih.gov/36436959/

12.  Templeman C, Marshall SF, Clarke CA, et al. Risk factors for surgically removed fibroids in a large cohort of teachers. Fertility and Sterility. 2009 Oct;92(4):1436-1446. DOI: 10.1016/j.fertnstert.2008.08.074. PMID: 19019355; PMCID: PMC2765807.
https://europepmc.org/article/PMC/2765807

13. Jie Lu, Jing Tian, Li Zhou, Lijun Meng, Sitan Chen, Changyang Ma, Jinmei Wang, Zhenhua Liu, Changqin Li, Wenyi Kang, "Phytochemistry and Biological Activities of Poria", Journal of Chemistry, vol. 2021, Article ID 6659775, 20 pages, 2021. https://doi.org/10.1155/2021/6659775
https://www.hindawi.com/journals/jchem/2021/6659775/



Κάντιντα
The antifungal effects of alcoholic extract of Ganoderma lucidum on Candida isolates  Author:  J. Chabavizadeh1; M. Sadeghi2; M. Chadeganipour3; M. Ghahri4; P. Dehghan3, 8th Trends in Medical Mycology, Organised under the auspices of EORTC-IDG and ECMM, 6-9 October 2017, Belgrade, Serbia  Date: 12 October 2017
https://www.aspergillus.org.uk/conference_abstracts/the-antifungal-effects-of-alcoholic-extract-of-ganoderma-lucidum-on-candida-isolates/



Αρρυθμία
Yan XF, Zhang ZM, Yao HY, Guan Y, Zhu JP, Zhang LH, Jia YL, Wang RW. Cardiovascular protection and antioxidant activity of the extracts from the mycelia of Cordyceps sinensis act partially via adenosine receptors. Phytother Res. 2013 Nov;27(11):1597-604. doi: 10.1002/ptr.4899. Epub 2012 Nov 28. PMID: 23192916.
https://pubmed.ncbi.nlm.nih.gov/23192916/



Καρδιακή ανεπάρκεια
Chen DG (1995) Effects of JinShuiBao Capsule on the Quality of Life of Patients with Heart Failure. Journal of Administration of Traditional Chinese Medicine 5: 40-43
https://link.springer.com/article/10.1007/s13205-013-0121-9



Καρδιομεταβολικό σύνδρομο
1.Kirk EP, Klein S. Pathogenesis and pathophysiology of the cardiometabolic syndrome. J Clin Hypertens (Greenwich). 2009 Dec;11(12):761-5. doi: 10.1111/j.1559-4572.2009.00054.x. PMID: 20021538; PMCID: PMC2859214.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859214/

2.Govindarajan G, Whaley-Connell A, Mugo M, Stump C, Sowers JR. The cardiometabolic syndrome as a cardiovascular risk factor. Am J Med Sci. 2005 Dec;330(6):311-8. doi: 10.1097/00000441-200512000-00009. PMID: 16355016.
https://www.amjmedsci.com/article/S0002-9629(15)32882-2/fulltext

3. Srivastava AK. Challenges in the treatment of cardiometabolic syndrome. Indian J Pharmacol. 2012 Mar;44(2):155-6. doi: 10.4103/0253-7613.93579. PMID: 22529466; PMCID: PMC3326903.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326903/

4. Sarafidis, Pantelis & Whaley-Connell, Adam & Sowers, James & Bakris, George. (2006). Cardiometabolic Syndrome and Chronic Kidney Disease: What Is the Link?. Journal of the cardiometabolic syndrome. 1. 58-65. 10.1111/j.0197-3118.2006.05470.x.
https://www.researchgate.net/publication/6163288_Cardiometabolic_Syndrome_and_Chronic_Kidney_Disease_What_Is_the_Link

5.National Kidney Foundation , ACR
https://www.kidney.org/kidneydisease/siemens_hcp_acr

6.Yerram, P., Karuparthi, P.R., Saab, G. et al. The cardiometabolic syndrome and chronic kidney disease. Curr Cardio Risk Rep 2, 95–100 (2008). https://doi.org/10.1007/s12170-008-0019-y
https://link.springer.com/article/10.1007/s12170-008-0019-y

7. Chen W, Chen Y. Cardiometabolic Syndrome and Vascular Calcification. Cardiometab Syndr J. 2022 Mar;2(1):1-21. https://doi.org/10.51789/cmsj.2022.2.e2
https://e-cmsj.org/DOIx.php?id=10.51789/cmsj.2022.2.e2

8. Ganoderma lucidum Polysaccharide Peptide Reduces Oxidative Stress and Improves Renal Function in Patient with Cardiometabolic Syndrome Syanindita Puspa Wardhani, Khilmi Ainun Nadliroh, Al Mazida Fauzil Aishaqeena, Fahriza Abid Sonia, Achmad Guntur Hermawan Suryo Adji, Intan Masyfufah Hanim, Rizkia Milladina Hidayatulloh, Anna Fuji Rahimah, Ardian Rizal, Peter Sugita, Ferry Sandra, Djanggan Sargowo, the indonesian biomedical journal,  Vo.2, April 2023, p . 106-93
https://inabj.org/index.php/ibj/article/view/2137/637

9. Gaweł S, Wardas M, Niedworok E, Wardas P. Dialdehyd malonowy (MDA) jako wskaźnik procesów peroksydacji lipidów w organizmie [Malondialdehyde (MDA) as a lipid peroxidation marker]. Wiad Lek. 2004;57(9-10):453-5. Polish. PMID: 15765761.
https://pubmed.ncbi.nlm.nih.gov/15765761/

10. Younus H. Therapeutic potentials of superoxide dismutase. Int J Health Sci (Qassim). 2018 May-Jun;12(3):88-93. PMID: 29896077; PMCID: PMC5969776.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969776/



Κατάθλιψη
1. Reddy MS. Depression: the disorder and the burden. Indian J Psychol Med. 2010 Jan;32(1):1-2. doi: 10.4103/0253-7176.70510. PMID: 21799550; PMCID: PMC3137804.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137804/

2. Depressive disorder (depression) 31 March 2023, World Health Organization
https://www.who.int/news-room/fact-sheets/detail/depression

3. Lépine JP, Briley M. The increasing burden of depression. Neuropsychiatr Dis Treat. 2011;7(Suppl 1):3-7. doi: 10.2147/NDT.S19617. Epub 2011 May 31. PMID: 21750622; PMCID: PMC3131101.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131101/

4. Ofosu FK, Yu X, Wang Q, Li H. Nutrient Optimization Using Response Surface Methodology for Simultaneous Biomass and Bioactive Compound Production by Lion's Mane Medicinal Mushroom, Hericium erinaceus (Agaricomycetes). Int J Med Mushrooms. 2016;18(3):215-26. doi: 10.1615/IntJMedMushrooms.v18.i3.40. PMID: 27481155.
https://pubmed.ncbi.nlm.nih.gov/27481155/

5. Penn E, Tracy DK. The drugs don't work? antidepressants and the current and future pharmacological management of depression. Ther Adv Psychopharmacol. 2012 Oct;2(5):179-88. doi: 10.1177/2045125312445469. PMID: 23983973; PMCID: PMC3736946.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736946/

6. Ioannidis, J.P. Effectiveness of antidepressants: an evidence myth constructed from a thousand randomized trials?. Philos Ethics Humanit Med 3, 14 (2008). https://doi.org/10.1186/1747-5341-3-14
https://peh-med.biomedcentral.com/articles/10.1186/1747-5341-3-14

7. Learn about mental health, Resource library, Beyond Blue
https://www.beyondblue.org.au/docs/default-source/resources/bl0125-antidepressant-medication-fact-sheet-acc.pdf?sfvrsn=fc1646eb_2

8. Antidepressants, Healthdirect Australia, May 2023
https://www.healthdirect.gov.au/antidepressants

9. Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7. doi: 10.2220/biomedres.31.231. PMID: 20834180.
https://pubmed.ncbi.nlm.nih.gov/20834180/

10. Kazutoyo Inanaga, Marked improvement of neurocognitive impairment after treatment with compounds from Hericium erinaceum: A case study of recurrent depressive disorder, Personalized Medicine Universe, Volume 3, 2014, Pages 46-48, ISSN 2186-4950, https://doi.org/10.1016/j.pmu.2014.02.004.
https://www.sciencedirect.com/science/article/abs/pii/S2186495014000108?via%3Dihub

11. Okamura H., Anno N., Tsuda A., Inokuchi T., Uchimura N., Inanaga K. The effects of Hericium erinaceus (Amyloban® 3399) on sleep quality and subjective well-being among female undergraduate students: A pilot study. Pers. Med. Universe. 2015;4:76–78. doi: 10.1016/j.pmu.2015.03.006
https://www.sciencedirect.com/science/article/abs/pii/S2186495015000103?via%3Dihub

12. Vigna L., Morelli F., Agnelli G.M., Napolitano F., Ratto D., Occhinegro A., Di Iorio C., Savino E., Girometta C., Brandalise F., et al. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? Evid.-Based Complement. Altern. Med. 2019;2019:7861297. doi: 10.1155/2019/7861297
https://pubmed.ncbi.nlm.nih.gov/31118969/

13. Chong, Pit Shan & Fung, Man & Kah Hui, Wong & Lim, Lee Wei. (2019). Therapeutic Potential of Hericium erinaceus for Depressive Disorder. International Journal of Molecular Sciences. 21. 10.3390/ijms21010163.
https://www.researchgate.net/publication/338079390_Therapeutic_Potential_of_Hericium_erinaceus_for_Depressive_Disorder

14. Chou MY, Ho JH, Huang MJ, Chen YJ, Yang MD, Lin LH, Chi CH, Yeh CH, Tsao TY, Tzeng JK, Hsu RJ, Huang PH, Lu WC, Li PH, Wang MF. Potential antidepressant effects of a dietary supplement from the chlorella and lion's mane mushroom complex in aged SAMP8 mice. Front Nutr. 2022 Sep 2;9:977287. doi: 10.3389/fnut.2022.977287. PMID: 36118772; PMCID: PMC9479623.
https://pubmed.ncbi.nlm.nih.gov/36118772/

15. Limanaqi F, Biagioni F, Busceti CL, Polzella M, Fabrizi C, Fornai F. Potential Antidepressant Effects of Scutellaria baicalensis, Hericium erinaceus and Rhodiola rosea. Antioxidants (Basel). 2020 Mar 12;9(3):234. doi: 10.3390/antiox9030234. PMID: 32178272; PMCID: PMC7139475.
https://pubmed.ncbi.nlm.nih.gov/32178272/

16. Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF 3rd. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry. 2013 May;202(5):329-35. doi: 10.1192/bjp.bp.112.118307. PMID: 23637108; PMCID: PMC3640214.
https://pubmed.ncbi.nlm.nih.gov/23637108/

17. Journal of Oriental Neuropsychiatry, Volume 23 Issue 2, Pages.1-12, 2012, The Korean Society of Oriental Neuropsychiatry, A Review Study in Treatment for Anxiety Disorder in Traditional Chinese Medicine, Lee, Seung-Hwan ; Kang, Min-Jeong; Lim, Jung-Hwa; Seong, Woo-Yong
https://koreascience.or.kr/article/JAKO201220962918995.page



Κολπική μαρμαρυγή
Rizal, Ardian & Sandra, Ferry & Rizki Fadlan, Muhamad & Sargowo, Djanggan. (2020). Ganoderma lucidum Polysaccharide Peptide Reduce Inflammation and Oxidative Stress in Patient with Atrial Fibrillation. The Indonesian Biomedical Journal. 12. 384-389. 10.18585/inabj.v12i4.1244.
https://www.researchgate.net/publication/347449665_Ganoderma_lucidum_Polysaccharide_Peptide_Reduce_Inflammation_and_Oxidative_Stress_in_Patient_with_Atrial_Fibrillation



Οξυτενή κονδυλώματα
Gao Q, Wu G, He D. [Effect of Cordyceps sinensis on the Th1/Th2 cytokines in patients with Condyloma Acuminatum]. Zhong Yao Cai. 2000 Jul;23(7):402-4. Chinese. PMID: 12575168.
https://pubmed.ncbi.nlm.nih.gov/12575168/



Κόπωση
1. The dangers of fatigue in the workplace, Texas Department of Insurance
https://www.tdi.texas.gov/tips/safety/fatigue.html

2. European Road Safety Observatory Road Safety Thematic Report - Fatigue, January 2021
https://road-safety.transport.ec.europa.eu/system/files/2021-07/road_safety_thematic_report_fatigue_tc_final.pdf

3. Fatigue, July 2022, Healthdirect Australia
https://www.healthdirect.gov.au/fatigue

4. Tiredness and fatigue, June 2023, NHS UK
https://www.nhs.uk/conditions/tiredness-and-fatigue/

5. Fatigue, Cleveland Clinic, 04/13/2023
https://my.clevelandclinic.org/health/symptoms/21206-fatigue



Κορωναϊός
1. Appl Microbiol Biotechnol, 102 (21), 9037-9051 Nov 2018 From Nutraceutical to Clinical Trial: Frontiers in Ganoderma Development Kai-Di Hsu, Kuan-Chen Cheng
https://pubmed.ncbi.nlm.nih.gov/30182215

2. J Ethnopharmacol, 68 (1-3), 129-36 1999 Dec 15 Antiviral Activities of Various Water and Methanol Soluble Substances Isolated From Ganoderma Lucidum S K Eo , Y S Kim, C K Lee, S S Han
https://pubmed.ncbi.nlm.nih.gov/10624872

3. Antibiot Khimioter, 59 (7-8), 41-8 2014 [Antiviral Properties of Basidiomycetes Metabolites] [Article in Russian] A V Avtonomova, L M Krasnopolskaya
https://pubmed.ncbi.nlm.nih.gov/25975107

4. Int J Med Mushrooms, 16 (5), 497-8 2014 Control of Oral Human Papillomavirus (HPV) by Medicinal Mushrooms, Trametes Versicolor and Ganoderma Lucidum: A Preliminary Clinical Trial Bruno Donatini
https://pubmed.ncbi.nlm.nih.gov/25271984

5. Appl Microbiol Biotechnol, 72 (3), 508-13 Sep 2006 A Laccase From the Medicinal Mushroom Ganoderma Lucidum H X Wang, T B Ng
https://pubmed.ncbi.nlm.nih.gov/16636832

6. Phytochemistry, 49 (6), 1651-7 Nov 1998 Anti-HIV-1 and anti-HIV-1-protease Substances From Ganoderma Lucidum S el-Mekkawy  1 , M R Meselhy, N Nakamura, Y Tezuka, M Hattori, N Kakiuchi, K Shimotohno, T Kawahata, T Otake
https://pubmed.ncbi.nlm.nih.gov/9862140

7. Chem Pharm Bull (Tokyo), 46 (10), 1607-12 Oct 1998 Triterpenes From the Spores of Ganoderma Lucidum and Their Inhibitory Activity Against HIV-1 Protease B S Min, N Nakamura, H Miyashiro, K W Bae, M Hattori
https://pubmed.ncbi.nlm.nih.gov/9810695

8. Bioinformation, 7 (8), 413-7 2011 Interaction of Ganoderic Acid on HIV Related Target: Molecular Docking Studies Rahmad Akbar, Wai Keat Yam
https://pubmed.ncbi.nlm.nih.gov/22347784

9. Exp Ther Med, 14 (4), 3273-3278 Oct 2017 Triterpenoids From Ganoderma lucidum Inhibit the Activation of EBV Antigens as Telomerase Inhibitors Dong-Shu Zheng, Liang-Shu Chen
https://pubmed.ncbi.nlm.nih.gov/28912878

10. J Nat Prod, 66 (12), 1582-5 Dec 2003 Lucidenic Acids P and Q, Methyl Lucidenate P, and Other Triterpenoids From the Fungus Ganoderma Lucidum and Their Inhibitory Effects on Epstein-Barr Virus Activation Kenji Iwatsuki, Toshihiro Akihisa, Harukuni Tokuda, Motohiko Ukiya, Manabu Oshikubo, Yumiko Kimura, Takeshi Asano, Atsushi Nomura, Hoyoku Nishino
https://pubmed.ncbi.nlm.nih.gov/14695801

11. Adv Exp Med Biol  , 1182, 217-242 2019 Preventive and Therapeutic Effect of Ganoderma (Lingzhi) on Liver Injury Zhiwei Qiu, Dandan Zhong, Baoxue Yang
https://pubmed.ncbi.nlm.nih.gov/31777021

12. Antibiot Khimioter, 55 (9-10), 14-8 2010 [Antiviral Activity of Aqueous Extracts and Polysaccharide Fractions From Mycelium and Fruit Bodies of Higher Fungi] [Article in Russian] I A Razumov, T A Kosogova, E I Kazachinskaia, L I Puchkova, N S Shcherbakova, I A Gorbunova, I N Mikhaĭlovskaia, V B Loktev, T V Tepliakova
https://pubmed.ncbi.nlm.nih.gov/21400748

13. Biochem Biophys Res Commun, 449 (3), 307-12 2014 Jul 4 Antiviral Effects of Two Ganoderma Lucidum Triterpenoids Against Enterovirus 71 Infection Wenjing Zhang, Junyan Tao, Xiaoping Yang, Zhuliang Yang, Li Zhang, Hongsheng Liu, Kailang Wu, Jianguo Wu
https://pubmed.ncbi.nlm.nih.gov/24845570

14. Sci Rep, 9 (1), 19059 2019 Dec 13 Discovery of Ganoderma Lucidum Triterpenoids as Potential Inhibitors Against Dengue Virus NS2B-NS3 Protease Shiv Bharadwaj, Kyung Eun Lee, Vivek Dhar Dwivedi, Umesh Yadava, Aleksha Panwar, Stuart J Lucas, Amit Pandey, Sang Gu Kang
https://pubmed.ncbi.nlm.nih.gov/31836806

15. J Ethnopharmacol, 95 (2-3), 265-72 Dec 2004 Possible Mode of Action of Antiherpetic Activities of a Proteoglycan Isolated From the Mycelia of Ganoderma Lucidum in Vitro Jing Liu, Fan Yang, Lin-Bai Ye, Xiao-Jun Yang, Khalid A Timani, Yi Zheng, Yu-Hua Wang
https://pubmed.ncbi.nlm.nih.gov/15507347

16. J Ethnopharmacol, 72 (1-2), 221-7 Sep 2000 Antiherpetic Activities of Acidic Protein Bound Polysacchride Isolated From Ganoderma Lucidum Alone and in Combinations With Acyclovir and Vidarabine K W Oh, C K Lee, Y S Kim, S K Eo, S S Han
https://pubmed.ncbi.nlm.nih.gov/10967475

17. J Ethnopharmacol, 68 (1-3), 175-81 1999 Dec 15 Antiherpetic Activities of Various Protein Bound Polysaccharides Isolated From Ganoderma Lucidum S K Eo, Y S Kim, C K Lee, S S Han
https://pubmed.ncbi.nlm.nih.gov/10624876

18. J Ethnopharmacol, 72 (3), 451-8 Oct 2000 Antiherpetic Activities of Acidic Protein Bound Polysacchride Isolated From Ganoderma Lucidum Alone and in Combinations With Interferons Y S Kim, S K Eo, K W Oh, C Lee, S S Han
https://pubmed.ncbi.nlm.nih.gov/10996285

19. J Ethnopharmacol, 72 (3), 475-81 Oct 2000 Possible Mode of Antiviral Activity of Acidic Protein Bound Polysaccharide Isolated From Ganoderma Lucidum on Herpes Simplex Viruses S K Eo, Y S Kim, C K Lee, S S Han
https://pubmed.ncbi.nlm.nih.gov/10996289

20. Molecules, 23 (3) 2018 Mar 13 Antitumour, Antimicrobial, Antioxidant and Antiacetylcholinesterase Effect of Ganoderma Lucidum Terpenoids and Polysaccharides: A Review Darija Cör, Željko Knez, Maša Knez Hrnčič
https://pubmed.ncbi.nlm.nih.gov/29534044

21. Front Pharmacol, 9, 1217 2018 Oct 25 eCollection 2018 Ganoderma: A Cancer Immunotherapy Review Yu Cao, Xiaowei Xu, Shujing Liu, Linfang Huang, Jian Gu
https://pubmed.ncbi.nlm.nih.gov/30410443

22. Recent Pat Inflamm Allergy Drug Discov  , 8 (2), 104-17 2014 Suppression of Inflammatory and Allergic Responses by Pharmacologically Potent Fungus Ganoderma Lucidum Neha Bhardwaj, Priya Katyal, Anil K Sharma
https://pubmed.ncbi.nlm.nih.gov/24948193

23.  Adv Exp Med Biol, 1181, 157-186 2019 Researches and Application of Ganoderma Spores Powder Jianhua Xu, Peng Li
https://pubmed.ncbi.nlm.nih.gov/31677143

24. Oncotarget, 9 (37), 24837-24856 2018 May 15 B-glucans From Grifola Frondosa and Ganoderma Lucidum in Breast Cancer: An Example of Complementary and Integrative Medicine Paola Rossi, Raffaele Difrancia, Vincenzo Quagliariello, Elena Savino, Paolo Tralongo, Cinzia Lucia Randazzo, Massimiliano Berretta
https://pubmed.ncbi.nlm.nih.gov/29872510

25. J Cell Mol Med, 22 (7), 3278-3297 Jul 2018 Chemical, Biochemical, Preclinical and Clinical Studies of Ganoderma Lucidum Polysaccharide as an Approved Drug for Treating Myopathy and Other Diseases in China Pengjiao Zeng, Zhihua Guo, Xuan Zeng, Cui Hao, Yiran Zhang, Meng Zhang, Yong Liu, Hui Li, Juan Li, Lijuan Zhang
https://pubmed.ncbi.nlm.nih.gov/29691994

26. Adv Exp Med Biol , 1182, 39-77 2019 Antitumor Effect of Ganoderma (Lingzhi) Mediated by Immunological Mechanism and Its Clinical Application Zhibin Lin, Lixin Sun
https://pubmed.ncbi.nlm.nih.gov/31777014

27.  Integr Med (Encinitas), 13 (1), 32-44 Feb 2014 Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology Alena G Guggenheim, Kirsten M Wright, Heather L Zwickey
https://pubmed.ncbi.nlm.nih.gov/26770080

28. Integr Cancer Ther, 14 (3), 249-57 May 2015 Ganoderma Lucidum for Cancer Treatment: We Are Close but Still Not There Shujie Cheng, Daniel Sliva
https://pubmed.ncbi.nlm.nih.gov/25626896

29. Tumour Biol, 37 (3), 2789-804 Mar 2016 Misconstrued Versatility of Ganoderma Lucidum: A Key Player in Multi-Targeted Cellular Signaling Balraj Singh Gill, Prateek Sharma, Raj Kumar, Sanjeev Kumar
https://pubmed.ncbi.nlm.nih.gov/26715282

30. Recent Pat Anticancer Drug Discov, 8 (3), 255-87 Sep 2013 Ganoderma Lucidum: A Potential for Biotechnological Production of Anti-Cancer and Immunomodulatory Drugs Bojana Boh
https://pubmed.ncbi.nlm.nih.gov/23227951

31. J Nanosci Nanotechnol, 5 (12), 2001-13 Dec 2005 Pharmacological and Anti-Tumor Activities of Ganoderma Spores Processed by Top-Down Approaches Xin Liu, Jiang-Hai Wang, Jian-Ping Yuan
https://pubmed.ncbi.nlm.nih.gov/16430134

32. Acta Pharmacol Sin, 25 (11), 1387-95 Nov 2004 Anti-tumor and Immunoregulatory Activities of Ganoderma Lucidum and Its Possible Mechanisms Zhi-bin Lin, Hui-na Zhang
https://pubmed.ncbi.nlm.nih.gov/15525457

33. Prog Mol Biol Transl Sci, 163, 179-219 2019 Ganoderma Lucidum Polysaccharide Used for Treating Physical Frailty in China Pengjiao Zeng, Yulong Chen, Lijuan Zhang, Maoqing Xing
https://pubmed.ncbi.nlm.nih.gov/31030748

34. Int J Biol Macromol, 121, 1160-1178 Jan 2019 Pharmacological Effects of Natural Ganoderma and Its Extracts on Neurological Diseases: A Comprehensive Review Chen Zhao, Chunchen Zhang, Zheng Xing, Zeeshan Ahmad, Jing-Song Li, Ming-Wei Chang
https://pubmed.ncbi.nlm.nih.gov/30342128

35. Curr Med Chem, 11 (11), 1423-30 Jun 2004 Immunomodulatory and Antimicrobial Effects of Some Traditional Chinese Medicinal Herbs: A Review Benny K H Tan, J Vanitha
https://pubmed.ncbi.nlm.nih.gov/15180575

36. Nutr Cancer, 53 (1), 11-7 2005 Anticancer Effects of Ganoderma Lucidum: A Review of Scientific Evidence John W M Yuen, Mayur Danny I Gohel
https://pubmed.ncbi.nlm.nih.gov/16351502

37.  Risk groups - advice and information, Norwegian Institute of Public Health
https://www.fhi.no/en/op/novel-coronavirus-facts-advice/facts-and-general-advice/risk-groups---advice-and-information/

38. Common Questions About the New Coronavirus Outbreak, American cancer society, March 13, 2020
https://www.cancer.org/latest-news/common-questions-about-the-new-coronavirus-outbreak.html

39. "Medicinal Mushrooms: Their therapeutic properties and current medical usage with special emphasis on cancer treatments" από τους Dr. Smith, Dr. Rowan και Dr. Sullivan,
www.academia.edu/305933/Medicinal_Mushrooms_Their_therapeutic_properties_and_current_medical_usage_with_special_emphasis_on_cancer_treatments

40. Cochrane Database Syst Rev, 2012, Ganoderma Lucidum (Reishi Mushroom) for Cancer Treatment, Xingzhong Jin, Julieta Ruiz Beguerie, Daniel Man-Yeun Sze, Godfrey C F Chan
https://pubmed.ncbi.nlm.nih.gov/22696372/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353236/

41. Int J Med Mushrooms, 2017, The Efficacy and Toxicity of Using the Lingzhi or Reishi Medicinal Mushroom, Ganoderma Lucidum (Agaricomycetes), and Its Products in Chemotherapy (Review), Martina Cizmarikova
https://pubmed.ncbi.nlm.nih.gov/29256841/

42. Immunol Invest, 2003, Effects of Ganopoly (A Ganoderma Lucidum Polysaccharide Extract) on the Immune Functions in Advanced-Stage Cancer Patients, Yihuai Gao, Shufeng Zhou, Wenqi Jiang, Min Huang, Xihu Dai
https://pubmed.ncbi.nlm.nih.gov/12916709/

43. Mycotherapy of cancer: an update on cytotoxic and antitumor activities of mushrooms, bioactive principles and molecular mechanisms of their action. Popović V, Živković J, Davidović S, Stevanović M, Stojković D. Curr Top Med Chem. 2013.
https://pubmed.ncbi.nlm.nih.gov/24083788

44. Cancer without Pharmacological Illusions and a Niche for Mycotherapy (Review). Zmitrovich IV, Belova NV, Balandaykin ME, Bondartseva MA, Wasser SP5. Int J Med Mushrooms. 2019;21(2):105-119.
https://pubmed.ncbi.nlm.nih.gov/30806218/

45. Ganoderma lucidum: a potent pharmacological macrofungus. Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS. Curr Pharm Biotechnol. 2009 Dec;10(8):717-42.
https://pubmed.ncbi.nlm.nih.gov/19939212/

46. Medicinal Mushrooms (PDQ®): Health Professional Version PDQ Integrative, Alternative, and Complementary Therapies Editorial Board In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002–. 2019 Oct 25.
https://pubmed.ncbi.nlm.nih.gov/27929633/

47. ARBS Annual Review of Biomedical Sciences Antitumor Properties of Ganoderma lucidum Polysaccharides and Terpenoids, in Annual Review of Biomedical Sciences · January 2011, Marcela Camargo, Ramon Kaneno
www.researchgate.net/publication/232722630_ARBS_Annual_Review_of_Biomedical_Sciences_Antitumor_Properties_of_Ganoderma_lucidum_Polysaccharides_and_Terpenoids

48. Integr Cancer Ther. 2015 May;14(3):249-57. doi: 10.1177/1534735414568721. Epub 2015 Jan 27. Ganoderma lucidum for cancer treatment: we are close but still not there. Cheng S1, Sliva D2.
https://pubmed.ncbi.nlm.nih.gov/25626896/

49. Hiroshima J Med Sci. 2010. A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas. Oka S, Tanaka S, Yoshida S, Hiyama T, Ueno Y, Ito M, Kitadai Y, Yoshihara M, Chayama K.
https://pubmed.ncbi.nlm.nih.gov/20518254/

50. “And What Other Medications Are You Taking?” John D. Gordan Wen-Yee Chay R. Kate Kelley , Andrew H. Ko Su-Pin Choo Alan P. Venook Show More, Journal of Clinical Oncology
https://ascopubs.org/doi/full/10.1200/jco.2010.32.8054?cited-by=yes&legid=jco%3B29%2F11%2Fe288

51. Cell Physiol Biochem. 2014. Protection against lung cancer patient plasma-induced lymphocyte suppression by Ganoderma lucidum polysaccharides. Sun LX1, Li WD, Lin ZB, Duan XS, Li XF, Yang N, Lan TF, Li M, Sun Y, Yu M, Lu J.
https://pubmed.ncbi.nlm.nih.gov/24525691/

52. Evid Based Complement Alternat Med. 2012. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X.
https://pubmed.ncbi.nlm.nih.gov/22203880/

53. Exp Ther Med. 2017 Oct;14(4):3273-3278. doi: 10.3892/etm.2017.4883. Epub 2017 Aug 3.
Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors.
Zheng DS1, Chen LS2.
http://europepmc.org/article/MED/28912878

54. Advice on coronavirus for people with cancer, 11 March 2020
https://lymphoma-action.org.uk/advice-coronavirus-people-cancer

55. Coronavirus advice for people receiving cancer treatment,   Updated 14 March 2020
https://www.cancer.ie/cancer-information-and-support/coronavirus-and-cancer-info-for-patients-families-volunteers/coronavirus-advice-for-for-people-receiving-cancer-treatment

56. Coronavirus (COVID-19) and cancer, 11 Mar 2020
https://www.cancerresearchuk.org/about-cancer/cancer-in-general/coronavirus-and-cancer

57. Coronavirus: What People With Breast Cancer Need to Know, March 12, 2020
https://www.breastcancer.org/about_us/press_room/news/coronavirus

58.  What you need to know about coronavirus (COVID-19), 18 March 2020
www.health.gov.au/news/health-alerts/novel-coronavirus-2019-ncov-health-alert/what-you-need-to-know-about-coronavirus-covid-19

59. Coronavirus and COVID-19, 18 March 2020, British Lung Foundation
www.blf.org.uk/support-for-you/coronavirus/what-is-coronavirus

60. Advice for people living with a lung condition, Lung Foundation Australia
https://lungfoundation.com.au/patients-carers/lung-health/coronavirus-disease-covid-19/advice-for-people-living-with-a-lung-condition/

61. Zhu, J et al. The Scientific Rediscovery of an Ancient Chinese Herbal Medicine: Cordyceps sinensis The Journal Of Alternative And Complementary Medicine [part 1]Volume 4, Number 3, 1998, pp. 289—303 [part 2] Volume 4, Number 4, 1998, pp. 429 - 457.

62.  Life Sci  , 68 (9), 1067-82 2001 Jan 19 Regulation of Bronchoalveolar Lavage Fluids Cell Function by the Immunomodulatory Agents From Cordyceps Sinensis Y C Kuo  1 , W J Tsai, J Y Wang, S C Chang, C Y Lin, M S Shiao
https://pubmed.ncbi.nlm.nih.gov/11212870/

63.  Zhongguo Zhong Yao Za Zhi  , 32 (15), 1566-8 Aug 2007 [Effect of Dongchong Xiacao Capsule on Airway Inflammation of Asthmatic Patients] [Article in Chinese] Ning-qun Wang  1 , Liang-duo Jiang, Xiao-mei Zhang, Zong-xin Li
https://pubmed.ncbi.nlm.nih.gov/17972591/

64.  The Essentials of Traditional Chinese Herbal Medicine Hardcover – December 1, 2003 by Liu Ganzhong

65.  Cordyceps: China's Healing Mushroom Mass Market Paperback – January 1, 1999 by Georges M. Halpern

66.  Zhong Xi Yi Jie He Xue Bao  , 8 (4), 341-6 Apr 2010 [Effects of Cordyceps Extract on Cytokines and Transcription Factors in Peripheral Blood Mononuclear Cells of Asthmatic Children During Remission Stage] [Article in Chinese] Wen Sun  1 , Jian Yu, Yu-min Shi, Hao Zhang, Ying Wang, Bing-bing Wu
https://pubmed.ncbi.nlm.nih.gov/20388474/

67.  Nutr Cancer, 12 (3), 271-8 1989 Natural Killer Cells, Vitamins, and Other Blood Components of Vegetarian and Omnivorous Men M Malter, G Schriever, U Eilber
https://pubmed.ncbi.nlm.nih.gov/2771803/

68.  Br J Nutr, 82 (5), 383-9 Nov 1999 Modulation of Human T-lymphocyte Functions by the Consumption of Carotenoid-Rich Vegetables B Watzl, A Bub, B R Brandstetter, G Rechkemmer
https://pubmed.ncbi.nlm.nih.gov/10673911/

69.  Am J Clin Nutr, 96 (6), 1429-36 Dec 2012 Effect of Fruit and Vegetable Consumption on Immune Function in Older People: A Randomized Controlled Trial Andrew Gibson, J David Edgar, Charlotte E Neville, Sarah E C M Gilchrist, Michelle C McKinley, Chris C Patterson, Ian S Young, Jayne V Woodside
https://pubmed.ncbi.nlm.nih.gov/23134881/

70. Int J Biol Sci. 2020; 16(10): 1708–1717. Published online 2020 Mar 15, Traditional Chinese Medicine in the Treatment of Patients Infected with 2019-New Coronavirus (SARS-CoV-2): A Review and Perspective Yang Yang, Md Sahidul Islam, Jin Wang, Yuan Li, Xin Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098036/

71. Review Article Published: 07 February 2020  Diagnosis, treatment, and prevention of 2019 novel coronavirus infection in children: experts’ consensus statement Kunling Shen, Yonghong Yang, Tianyou Wang, Dongchi Zhao, Yi Jiang, Runming Jin, Yuejie Zheng, Baoping Xu, Zhengde Xie, Likai Lin, Yunxiao Shang, Xiaoxia Lu, Sainan Shu, Yan Bai, Jikui Deng, Min Lu, Leping Ye, Xuefeng Wang, Yongyan Wang, Liwei Gao, China National Clinical Research Center for Respiratory Diseases, National Center for Children’s Health, Beijing, China, Group of Respirology, Chinese Pediatric Society, Chinese Medical Association, Chinese Medical Doctor Association Committee on Respirology Pediatrics, China Medicine Education Association Committee on Pediatrics, Chinese Research Hospital Association Committee on Pediatrics, Chinese Non-government Medical Institutions Association Committee on Pediatrics, China Association of Traditional Chinese Medicine, Committee on Children’s Health and Medicine Research, China News of Drug Information Association, Committee on Children’s Safety Medication & Global Pediatric Pulmonology Alliance  World Journal of Pediatrics (2020)
https://link.springer.com/article/10.1007%2Fs12519-020-00343-7
https://pubmed.ncbi.nlm.nih.gov/32034659/

72. Global Health Strategies shift as coronavirus pandemic looms, Jon Cohen, Kai Kupferschmidt, 28 Feb 2020: Vol. 367, Issue 6481, pp. 962-963
https://science.sciencemag.org/content/367/6481/962/tab-e-letters
https://pubmed.ncbi.nlm.nih.gov/32108093/

73.  BMC Complement Altern Med, 19 (1), 77 2019 Mar 29 Immunomodulatory Effects of a Mycelium Extract of Cordyceps (Paecilomyces Hepiali; CBG-CS-2): A Randomized and Double-Blind Clinical Trial Su-Jin Jung, Eun-Soo Jung, Eun-Kyung Choi, Hong-Sig Sin, Ki-Chan Ha, Soo-Wan Chae
https://pubmed.ncbi.nlm.nih.gov/30925876
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441223/

74.  Zhongguo Zhong Yao Za Zhi. 2010 Oct;35(20):2777-81. [Pharmacological Effects of Bailing Capsule and Its Application in Lung Disease Research] Huijuan Xu  1 , Shiyue Li https://pubmed.ncbi.nlm.nih.gov/21246839/

75. Review, Published: 25 May 2020  Predictive symptoms and comorbidities for severe COVID-19 and intensive care unit admission: a systematic review and meta-analysis, Vageesh Jain & Jin-Min Yuan https://link.springer.com/article/10.1007/s00038-020-01390-7

76. Can medicinal mushrooms have prophylactic or therapeutic effect against COVID‐19 and its pneumonic superinfection and complicating inflammation? Geir Hetland Egil Johnson Soosaipillai V. Bernardshaw Bjørn Grinde First published: 13 July 2020
https://onlinelibrary.wiley.com/doi/full/10.1111/sji.12937

77. Nutraceuticals and herbal extracts: A ray of hope for COVID‑19 and related infections (Review)
https://www.spandidos-publications.com/10.3892/ijfn.2020.6

78.  Chem Biol Drug Des  . 2020 Dec 7. doi: 10.1111/cbdd.13812. Online ahead of print. Repurposing potential of FDA-approved and investigational drugs for COVID-19 targeting SARS-CoV-2 spike and main protease and validation by machine learning algorithm Akalesh Kumar Verma, Rohit Aggarwal
https://pubmed.ncbi.nlm.nih.gov/33289334/

79. Kaymakcı, Mehmet & Güler, Eray. (2020). Promising Potential Pharmaceuticals from the Genus Cordyceps for COVID-19 Treatment: A Review Study. Bezmialem Science. 8. 140-144. 10.14235/bas.galenos.2020.4532.
https://www.researchgate.net/publication/347738030_Promising_Potential_Pharmaceuticals_from_the_Genus_Cordyceps_for_COVID-19_Treatment_A_Review_Study

80. The Role of Ganoderma lucidum Uptake on Some Hematological and Immunological Response in Patients with Coronavirus (COVID-19), Sys Rev Pharm 2020;11(8):537-541 A multifaceted review journal in the field of pharmacy,  Miqdam M. Obaid AL-jumaili, Fahad K. Y. Al-dulaimi, Mohammed A. Ajeel
https://www.sysrevpharm.org/articles/the-role-of-ganoderma-lucidum-uptake-on-some-hematological-and-immunological-response-in-patients-with-coronavirus-covid.pdf

81. Mallard, M. G.. Gazzetta Medica Italiana Archivio per le Scienze Mediche ; 181(3):177-182, 2022. Article in Italian | EMBASE | ID: covidwho-1988845
https://pesquisa.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/pt/covidwho-1988845?lang=en

82. Jędrejko KJ, Lazur J, Muszyńska B. Cordyceps militaris: An Overview of Its Chemical Constituents in Relation to Biological Activity. Foods. 2021 Oct 30;10(11):2634. doi: 10.3390/foods10112634. PMID: 34828915; PMCID: PMC8622900.
https://pubmed.ncbi.nlm.nih.gov/34828915/

83. Verma AK. Cordycepin: a bioactive metabolite of Cordyceps militaris and polyadenylation inhibitor with therapeutic potential against COVID-19. J Biomol Struct Dyn. 2022 May;40(8):3745-3752. doi: 10.1080/07391102.2020.1850352. Epub 2020 Nov 23. PMID: 33225826; PMCID: PMC7754931.
https://pubmed.ncbi.nlm.nih.gov/33225826/

84. A rare Tibetan worm may hold key to long-acting COVID vaccines  27 August 2021 ,  Tania Ewing, Monash University
https://www.monash.edu/discovery-institute/news-and-events/news/2021-articles/a-rare-tibetan-worm-may-hold-key-to-long-acting-covid-vaccines

85. Chellapandi , P.,Saranya , S.,Cordycepin and its Nucleoside Analogs for the Treatment of Systemic COVID-19 Infection,Coronaviruses, volume 3, issue 1, pages 3-8, year 2022, issn 2666-7967/2666-7975, doi 10.2174/2666796702666210910111551,
https://www.ingentaconnect.com/content/ben/covid/2022/00000003/00000001/art00004

86. Cochrane Central Register of Controlled Trials A study of Cordyceps Capsules as an Add-On Therapy in patients with moderate COVID 19 Infection CTRI/2020/09/028131 https://trialsearch.who.int/Trial2.aspx?TrialID=CTRI/2020/09/028131, 2020 | added to CENTRAL: 30 November 2020 | 2020 Issue 11
https://www.cochranelibrary.com/central/doi/10.1002/central/CN-02186148/full

87. Dubhashi S, Sinha S, Dwivedi S, Ghanekar J, Kadam S, Samant P, Datta V, Singh S, Chaudry IH, Gurmet P, Kelkar H, Mishra R, Galwankar S, Agrawal A. Early Trends to Show the Efficacy of Cordyceps militaris in Mild to Moderate COVID Inflammation. Cureus. 2023 Aug 18;15(8):e43731. doi: 10.7759/cureus.43731. PMID: 37727187; PMCID: PMC10505833.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505833/

88. Examining the Function of Cs4 on Post-COVID-19 Disorders, ClinicalTrials.gov Identifier: NCT06054438,  First Posted : September 26, 2023 Last Update Posted : April 11, 2024
https://classic.clinicaltrials.gov/ct2/show/NCT06054438
 

Κτηνιατρική
1. Nutrients. 2021 Mar 21;13(3):1008. doi: 10.3390/nu13031008. Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study Xiao-Qian Xie, Yan Geng, Qijie Guan, Yilin Ren, Lin Guo, Qiqi Lv, Zhen-Ming Lu, Jin-Song Shi, Zheng-Hong Xu.

2. Nagano M, Shimizu K, Kondo R, Hayashi C, Sato D, Kitagawa K, Ohnuki K. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7. doi: 10.2220/biomedres.31.231. PMID: 20834180.
https://pubmed.ncbi.nlm.nih.gov/20834180/

3. Kazutoyo Inanaga, Marked improvement of neurocognitive impairment after treatment with compounds from Hericium erinaceum: A case study of recurrent depressive disorder, Personalized Medicine Universe, Volume 3, 2014, Pages 46-48, ISSN 2186-4950, https://doi.org/10.1016/j.pmu.2014.02.004.
https://www.sciencedirect.com/science/article/abs/pii/S2186495014000108?via%3Dihub

4. Okamura H., Anno N., Tsuda A., Inokuchi T., Uchimura N., Inanaga K. The effects of Hericium erinaceus (Amyloban® 3399) on sleep quality and subjective well-being among female undergraduate students: A pilot study. Pers. Med. Universe. 2015;4:76–78. doi: 10.1016/j.pmu.2015.03.006
https://www.sciencedirect.com/science/article/abs/pii/S2186495015000103?via%3Dihub

5. Vigna L., Morelli F., Agnelli G.M., Napolitano F., Ratto D., Occhinegro A., Di Iorio C., Savino E., Girometta C., Brandalise F., et al. Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers? Evid.-Based Complement. Altern. Med. 2019;2019:7861297. doi: 10.1155/2019/7861297
https://pubmed.ncbi.nlm.nih.gov/31118969/

6. Basko, Ihor & Dohmen, Laurie. (2023). Lion’s Mane (Hericium erinaceus): A Potential Treatment for Neurologic Disorders in Veterinary Medicine. Journal of the American Holistic Veterinary Medical Association. 70. 15-20. 10.56641/PSSJ9210.
https://www.ahvma.org/journal/pssj9210/



Στυτική δυσλειτουργία
1. Jiraungkoorskul K, Jiraungkoorskul W. Review of Naturopathy of Medical Mushroom, Ophiocordyceps Sinensis, in Sexual Dysfunction. Pharmacogn Rev. 2016 Jan-Jun;10(19):1-5. doi: 10.4103/0973-7847.176566. PMID: 27041868; PMCID: PMC4791983.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791983/

2. Drewes SE, George J, Khan F. Recent findings on natural products with erectile-dysfunction activity. Phytochemistry. 2003 Apr;62(7):1019-25. doi: 10.1016/s0031-9422(02)00621-0. PMID: 12591255.
https://www.academia.edu/4392499/Recent_findings_on_natural_products_with_erectile_dysfunction_activity_2

3. Washington University in St. Louis, Himalayan Viagra fuels caterpillar fungus gold rush, Gerry Everding October 28, 2014,
https://source.wustl.edu/2014/10/himalayan-viagra-fuels-caterpillar-fungusgold-rush/

4.  Elsevier, Pharmaceutical Sciences, ‘Himalayan Viagra’ Is Threatened by Fervent Chinese Demand and Climate Change, Prayan Pokharel, July 21, 2017
https://scitechconnect.elsevier.com/himalayan-viagra-threatened-fervent-chinese-climate-change/

5. Stone R. Mycology. Last stand for the body snatcher of the Himalayas? Science. 2008 Nov 21;322(5905):1182. doi: 10.1126/science.322.5905.1182. PMID: 19023056.
https://www.science.org/doi/10.1126/science.322.5905.1182?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

6. Martel J, Ko YF, Liau JC, Lee CS, Ojcius DM, Lai HC, Young JD. Myths and Realities Surrounding the Mysterious Caterpillar Fungus. Trends Biotechnol. 2017 Nov;35(11):1017-1021. doi: 10.1016/j.tibtech.2017.06.011. PMID: 29055355.
https://pubmed.ncbi.nlm.nih.gov/29055355/

7. Qiu, J. Overharvesting leaves ‘Himalayan Viagra’ fungus feeling short. Nature (2013). https://doi.org/10.1038/nature.2013.12308
https://www.nature.com/articles/nature.2013.12308

8. The Scientific Rediscovery of an Ancient Chinese Herbal Medicine: Cordyceps Sinensis, Part I, Jia-Shi Zhu, M.D., Ph.D., Georges M. Halpern, M.D., Ph.D., Kenneth Jones, The Journal of Alternative and Complementary Medicine, Volume 4, Number 3, 1998, pp. 289-303,Mary Ann Liebert, Inc.

9. Paul Stamets «Mycelium Running: How Mushrooms Can Help Save the World”, σελίδα 41, Πίνακας "Cross-Index of Mushrooms and Targeted Therapeutic Effects"
https://www.amazon.com/Mycelium-Running-Mushrooms-Help-World/dp/1580085792/ref=sr_1_1?ie=UTF8&qid=1406986056&sr=8-1&keywords=Mycelium+Running%3A+How+Mushrooms+Can+Help+Save+the+World



Νόσος lyme
1. About Julia Behrens,
https://herbal-consultant.com/about/

2. Lost in Lyme: The Therapeutic Use of Medicinal Plants in Supporting People with Lyme Disease By Julia Behrens (Author) Daphne Lambert (Contributor)
https://www.whsmith.co.uk/products/lost-in-lyme-the-therapeutic-use-of-medicinal-plants-in-supporting-people-with-lyme-disease/julia-behrens/daphne-lambert/paperback/9781801520126.html

3. Lost in Lyme: The Therapeutic Use of Medicinal Plants in Supporting People with Lyme Disease By Julia Behrens (Author) Daphne Lambert (Contributor)
https://books.google.gr/books?id=iRvBEAAAQBAJ&pg=PT58&lpg=PT58&dq=ganoderma+lyme&source=bl&ots=C5RxbXIyFB&sig=ACfU3U30bZ-jhXpFGQrcQ05s5w4ezl2vAw&hl=el&sa=X&ved=2ahUKEwjWt7WozOOAAxWWR_EDHRUxB4k4HhDoAXoECCEQAw#v=onepage&q=ganoderma%20lyme&f=false

4. Cordyceps – ancient fungus for modern health benefits, Restorative Health Clinic
https://restorativehealthclinic.com/cordyceps-ancient-fungus-for-modern-health-benefits/

5. Ciampi E, Uribe-San-Martin R, Cárcamo C, et al. Efficacy of andrographolide in not active progressive multiple sclerosis: A prospective exploratory double-blind, parallel-group, randomized, placebo-controlled trial. BMC Neurol. 2020;20(1):1-10.
https://www.naturalmedicinejournal.com/journal/could-andrographolide-andrographis-paniculata-help-multiple-sclerosis

6. Andrographis, Dr. Bill Rawls
https://rawlsmd.com/herbs/andrographis

7. Feng J, Leone J, Schweig S and Zhang Y (2020) Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi. Front. Med. 7:6. doi: 10.3389/fmed.2020.00006
https://www.frontiersin.org/articles/10.3389/fmed.2020.00006/full

8. May 16, 2022May 16, 2022 by Kussin Clarissa Welcome to Tick Season  Frances T Meredith, MD
https://carolinatotalwellness.com/blog/index.php/2022/05/16/welcome-to-tick-season/



Μεθερπητική νευραλγία
1. Hijikata Y, Yamada S. Effect of Ganoderma lucidum on postherpetic neuralgia. Am J Chin Med. 1998;26(3-4):375-81. doi: 10.1142/S0192415X98000415. PMID: 9862025.
https://pubmed.ncbi.nlm.nih.gov/9862025/

2. Hijikata Y, Yamada S, Yasuhara A. Herbal mixtures containing the mushroom Ganoderma lucidum improve recovery time in patients with herpes genitalis and labialis. J Altern Complement Med. 2007 Nov;13(9):985-7. doi: 10.1089/acm.2006.6297. PMID: 18047445.
https://pubmed.ncbi.nlm.nih.gov/18047445/

3. Zhu P, Woo B Nonprescription Products of Internet Retailers for the Prevention and Management of Herpes Zoster and Postherpetic Neuralgia: Analysis of Consumer Reviews on Amazon JMIR Dermatol 2021;4(1):e24971
https://derma.jmir.org/2021/1/e24971/

4. Sijia Wu, Siyuan Zhang, Bo Peng, Dechao Tan, Mingyue Wu, Jinchao Wei, Yitao Wang, Hua Luo, Ganoderma lucidum: a comprehensive review of phytochemistry, efficacy, safety and clinical study, Food Science and Human Wellness, Volume 13, Issue 2, 2024, Pages 568-596, ISSN 2213-4530,
https://www.sciencedirect.com/science/article/pii/S2213453023001854

5. Zając S., Krzyśko-Łupicka T., Walosik A., Chmielewski J., Wójtowicz B., Nowak-Starz G. 2023. Pharmacological properties and use of Ganoderma lucidum in modern medicine. J. Elem., 28(1): 161-172. DOI: 10.5601/jelem.2022.27.4.2350



Μικροβίωμα του εντέρου
Nutrients. 2021 Mar 21;13(3):1008. doi: 10.3390/nu13031008. Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study Xiao-Qian Xie, Yan Geng, Qijie Guan, Yilin Ren, Lin Guo, Qiqi Lv, Zhen-Ming Lu, Jin-Song Shi, Zheng-Hong Xu.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8004025/



Νευρασθένεια
Tang W, Gao Y, Chen G, Gao H, Dai X, Ye J, Chan E, Huang M, Zhou S. A randomized, double-blind and placebo-controlled study of a Ganoderma lucidum polysaccharide extract in neurasthenia. J Med Food. 2005 Spring;8(1):53-8. doi: 10.1089/jmf.2005.8.53. PMID: 15857210.
https://pubmed.ncbi.nlm.nih.gov/15857210/



Ουρικό οξύ
1. Clinical Trial Zhongguo Zhong Xi Yi Jie He Za Zhi  . 2004 Sep;24(9):808-10. [Clinical study on application of bailing capsule after renal transplantation] [Article in Chinese] Ming Sun, Yu-ru Yang, Yi-Ping Lu, Rui Gao, Li Wang, Jia Wang, Keshi Tang
https://pubmed.ncbi.nlm.nih.gov/15495826/

2. Controlled Clinical Trial Zhongguo Zhong Xi Yi Jie He Za Zhi  . 2009 Nov;29(11):975-8. [Clinical application and exploration on mechanism of action of Cordyceps sinensis mycelia preparation for renal transplantation recipients] [Article in Chinese] Chen-guang Ding, Pu-xun Tian, Zhan-kui Jin
https://pubmed.ncbi.nlm.nih.gov/20329604/

3. Randomized Controlled Trial Transplant Proc  . 2009 Jun;41(5):1565-9. doi: 10.1016/j.transproceed.2009.02.085. Clinical application of Cordyceps sinensis on immunosuppressive therapy in renal transplantation Y Li, W-J Xue, P-X Tian, X-M Ding, H Yan, X-M Pan, X-S Feng
https://pubmed.ncbi.nlm.nih.gov/19545680/

4. Review Cochrane Database Syst Rev  . 2015 Oct 12;(10):CD009698. doi: 10.1002/14651858.CD009698.pub2. Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients Tao Hong, Minghua Zhang, Junming Fan
https://pubmed.ncbi.nlm.nih.gov/26457607/

5. Review Complement Ther Med  . 2017 Feb;30:84-92. doi: 10.1016/j.ctim.2016.12.007. Epub 2016 Dec 21. Efficacy of Cordyceps sinensis as an adjunctive treatment in kidney transplant patients: A systematic-review and meta-analysis Bee Yean Ong, Zoriah Aziz
https://pubmed.ncbi.nlm.nih.gov/28137532/
6. Nutrients. 2021 Mar 21;13(3):1008. doi: 10.3390/nu13031008. Influence of Short-Term Consumption of Hericium erinaceus on Serum Biochemical Markers and the Changes of the Gut Microbiota: A Pilot Study Xiao-Qian Xie, Yan Geng, Qijie Guan, Yilin Ren, Lin Guo, Qiqi Lv, Zhen-Ming Lu, Jin-Song Shi, Zheng-Hong Xu.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8004025/

7. Wachtel-Galor S, Szeto YT, Tomlinson B, Benzie IF. Ganoderma lucidum ('Lingzhi'); acute and short-term biomarker response to supplementation. Int J Food Sci Nutr. 2004 Feb;55(1):75-83. doi: 10.1080/09637480310001642510. PMID: 14630595.
https://pubmed.ncbi.nlm.nih.gov/14630595/



Συμπτώματα κατώτερου ουροποιητικού συστήματος
1. Noguchi M, Kakuma T, Tomiyasu K, Kurita Y, Kukihara H, Konishi F, Kumamoto S, Shimizu K, Kondo R, Matsuoka K. Effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: a double-blind, placebo-controlled randomized and dose-ranging study. Asian J Androl. 2008 Jul;10(4):651-8. doi: 10.1111/j.1745-7262.2008.00336.x. Epub 2007 Dec 20. PMID: 18097503.
https://pubmed.ncbi.nlm.nih.gov/18097503/

2. Noguchi M, Kakuma T, Tomiyasu K, Yamada A, Itoh K, Konishi F, Kumamoto S, Shimizu K, Kondo R, Matsuoka K. Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms. Asian J Androl. 2008 Sep;10(5):777-85. doi: 10.1111/j.1745-7262.2008.00361.x. Epub 2007 Dec 20. PMID: 18097505.
https://pubmed.ncbi.nlm.nih.gov/18097505/



Οστεοαρθρίτιδα
1. Abramoff B, Caldera FE. Osteoarthritis: Pathology, Diagnosis, and Treatment Options. Med Clin North Am. 2020 Mar;104(2):293-311. doi: 10.1016/j.mcna.2019.10.007. Epub 2019 Dec 18. PMID: 32035570.
https://pubmed.ncbi.nlm.nih.gov/32035570/

2. Martel-Pelletier J, Barr AJ, Cicuttini FM, Conaghan PG, Cooper C, Goldring MB, Goldring SR, Jones G, Teichtahl AJ, Pelletier JP. Osteoarthritis. Nat Rev Dis Primers. 2016 Oct 13;2:16072. doi: 10.1038/nrdp.2016.72. PMID: 27734845.
https://pubmed.ncbi.nlm.nih.gov/27734845/

3. Pereira D, Ramos E, Branco J. Osteoarthritis. Acta Med Port. 2015 Jan-Feb;28(1):99-106. doi: 10.20344/amp.5477. Epub 2015 Feb 27. PMID: 25817486.
https://pubmed.ncbi.nlm.nih.gov/25817486/

4. Glyn-Jones S, Palmer AJ, Agricola R, Price AJ, Vincent TL, Weinans H, Carr AJ. Osteoarthritis. Lancet. 2015 Jul 25;386(9991):376-87. doi: 10.1016/S0140-6736(14)60802-3. Epub 2015 Mar 4. PMID: 25748615.
https://pubmed.ncbi.nlm.nih.gov/25748615/

5. Xie C, Chen Q. Adipokines: New Therapeutic Target for Osteoarthritis? Curr Rheumatol Rep. 2019 Dec 7;21(12):71. doi: 10.1007/s11926-019-0868-z. PMID: 31813080; PMCID: PMC7291783.
https://pubmed.ncbi.nlm.nih.gov/31813080/

6. Xia B, Di Chen, Zhang J, Hu S, Jin H, Tong P. Osteoarthritis pathogenesis: a review of molecular mechanisms. Calcif Tissue Int. 2014 Dec;95(6):495-505. doi: 10.1007/s00223-014-9917-9. Epub 2014 Oct 14. PMID: 25311420; PMCID: PMC4747051.
https://pubmed.ncbi.nlm.nih.gov/25311420/

7. Taruc-Uy RL, Lynch SA. Diagnosis and treatment of osteoarthritis. Prim Care. 2013 Dec;40(4):821-36, vii. doi: 10.1016/j.pop.2013.08.003. Epub 2013 Sep 26. PMID: 24209720.
https://pubmed.ncbi.nlm.nih.gov/24209720/

8. Wang LJ, Zeng N, Yan ZP, Li JT, Ni GX. Post-traumatic osteoarthritis following ACL injury. Arthritis Res Ther. 2020 Mar 24;22(1):57. doi: 10.1186/s13075-020-02156-5. PMID: 32209130; PMCID: PMC7092615.
https://pubmed.ncbi.nlm.nih.gov/32209130/

9. How Fat Affects Osteoarthritis, Arthritis Foundation,
https://www.arthritis.org/health-wellness/about-arthritis/related-conditions/other-diseases/how-fat-affects-osteoarthritis

10. Osteoarthritis and Sleep, Arthritis Foundation, 3/15/22
https://www.arthritis.org/health-wellness/healthy-living/managing-pain/fatigue-sleep/osteoarthritis-and-sleep

11. How sleep deprivation can cause inflammation January 11, 2022, Harvard Health Publishing,
https://www.health.harvard.edu/sleep/how-sleep-deprivation-can-cause-inflammation

12. Buck AN, Vincent HK, Newman CB, Batsis JA, Abbate LM, Huffman KF, Bodley J, Vos N, Callahan LF, Shultz SP. Evidence-Based Dietary Practices to Improve Osteoarthritis Symptoms: An Umbrella Review. Nutrients. 2023 Jul 6;15(13):3050. doi: 10.3390/nu15133050. PMID: 37447376; PMCID: PMC10347206.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347206/

13.  Healthy eating tips for people with arthritis, British Nutrition Foundation, August 2019
https://www.nutrition.org.uk/health-conditions/bone-and-joint-health/healthy-eating-tips-for-people-with-arthritis/

14. Healthy eating when you have OA, Government of Alberta, October 2, 2020
https://myhealth.alberta.ca/Alberta/Pages/Healthy-eating-when-you-have-OA.aspx

15. Mayo Clinic Minute: Fighting arthritis with food, November 5, 2019,
https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-minute-fighting-arthritis-with-food/

16.  Living with - Osteoarthritis, NHS of UK, 20 March 2023
https://www.nhs.uk/conditions/osteoarthritis/living-with/

17. Osteoarthritis, University of Maryland Medical System
https://health.umms.org/2020/12/21/control-osteoarthritis-symptoms/

18. Cooper, I., Brukner, P., Devlin, B.L. et al. An anti-inflammatory diet intervention for knee osteoarthritis: a feasibility study. BMC Musculoskelet Disord 23, 47 (2022). https://doi.org/10.1186/s12891-022-05003-7
https://bmcmusculoskeletdisord.biomedcentral.com/articles/10.1186/s12891-022-05003-7

19. What Can I Eat to Help Ease the Pain of Osteoarthritis?, Dietitians of Canada, December 7, 2022
https://www.unlockfood.ca/en/Articles/Seniors-nutrition/What-Can-I-Eat-to-Help-Ease-the-Pain-of-Osteoarthritis.aspx

20. Arthritis and diet, Department of Health, State Government of Victoria, Australia ,
https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/arthritis-and-diet

21.  Osteoarthritis Self-Management, Arthritis Society Canada,
https://arthritis.ca/about-arthritis/arthritis-types-(a-z)/types/osteoarthritis/osteoarthritis-self-management#weight_management

22. Foods to Help You Fight Arthritis ,  May 30, 2018 , University of Pennsylvania
https://www.pennmedicine.org/updates/blogs/musculoskeletal-and-rheumatology/2018/may/seven-foods-to-help-you-fight-arthritis

23. Food is Medicine: A Project to Unify and Advance Collective Action, Office of Disease Prevention and Health Promotion
https://health.gov/our-work/nutrition-physical-activity/food-medicine

24.  Food Is Medicine, UNIVERSITY of WISCONSIN–MADISON
https://www.fammed.wisc.edu/food-is-medicine/

25. Volpp KG, Berkowitz SA, Sharma SV, Anderson CAM, Brewer LV, Elkind MSV, Gardner CD, Gervis JE, Harrington RA, Herrero M, Lichtenstein AH, McClellan M, Muse J, Roberto CA, Zachariah JPV; on behalf of the American Heart Association. Food Is Medicine: a presidential advisory from the American Heart Association. Circulation. 2023;148:1417–1439. doi: 10.1161/CIR.0000000000001182
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001182

26. Food as Medicine The Healing Potential of Food, american college of lifestyle medicine
https://lifestylemedicine.org/nutrition-as-medicine/

27. Tufts University ,  What is “Food is Medicine?”
https://tuftsfoodismedicine.org/

28.  Food is Medicine Interventions , Massachusetts
https://foodismedicinema.org/food-is-medicine-interventions

29.  Downer S, Berkowitz S A, Harlan T S, Olstad D L, Mozaffarian D. Food is medicine: actions to integrate food and nutrition into healthcare BMJ 2020; 369 :m2482 doi:10.1136/bmj.m2482
https://www.bmj.com/content/369/bmj.m2482

30. Platkin, C., Cather, A., Butz, L., Garcia, I., Gallanter, M., Leung, MM., Food As Medicine: Overview and Report: How Food and Diet Impact the Treatment of Disease and Disease Management. Center for Food As Medicine and Hunter College NYC Food Policy Center; March 30, 2022, available at foodmedcenter.org and nycfoodpolicy.org.
https://foodmedcenter.org/wp-content/uploads/foodasmedicine.pdf

31. The Aspen Institute, Downer S, Clippinger E, Kummer C. Food is Medicine Research Action Plan. Published Jan. 27, 2022.
https://www.aspeninstitute.org/programs/food-and-society-program/food-is-medicine-project/

32.  Food as Medicine , Academy of Nutrition and Dietetics ,
https://www.eatrightfoundation.org/resources/food-as-medicine

33. Clinton CM, O'Brien S, Law J, Renier CM, Wendt MR. Whole-foods, plant-based diet alleviates the symptoms of osteoarthritis. Arthritis. 2015;2015:708152. doi: 10.1155/2015/708152. Epub 2015 Feb 28. PMID: 25815212; PMCID: PMC4359818. https://pubmed.ncbi.nlm.nih.gov/25815212/



Στοματική Υγεία
1. Oral Health, worldwide, World Dental Federation, 2015
https://www.fdiworlddental.org/sites/default/files/2020-11/2015_wohd-whitepaper-oral_health_worldwide.pdf

2. Basics of Oral Health,  January 4, 2023     Source: Division of Oral Health, National Center for Chronic Disease Prevention and Health Promotion
https://www.cdc.gov/oralhealth/basics/index.html

3. Al-attas, Safia & Zahran, Fat’heya & Turkistany, Shereen. (2016). Nigella sativa and its active constituent thymoquinone in oral health. Saudi Medical Journal. 37. 235-244. 10.15537/smj.2016.3.13006.
https://www.researchgate.net/publication/295839793_Nigella_sativa_and_its_active_constituent_thymoquinone_in_oral_health

4. Key facts about oral health, fdi world dental federation
https://www.fdiworlddental.org/key-facts-about-oral-health

5. Samuel S. Antwi-Baffour, Ajediran I. Bello, David N. Adjei, Seidu A. Mahmood, Patrick F. Ayeh-Kumi. (2014). The Place of Traditional Medicine in the African Society: The Science, Acceptance and Support. American Journal of Health Research, 2(2), 49-54. https://doi.org/10.11648/j.ajhr.20140202.13
https://www.sciencepublishinggroup.com/article/10.11648/ajhr.20140202.13

6. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/

7. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/

8. Ahmad, Md Faruque. (2018). Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 107. 507-519. 10.1016/j.biopha.2018.08.036.
https://www.sciencedirect.com/science/article/abs/pii/S0753332218326349

9. Oke MA, Afolabi FJ, Oyeleke OO, Kilani TA, Adeosun AR, Olanbiwoninu AA and Adebayo EA (2022) Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa. Front. Pharmacol. 13:952027. doi: 10.3389/fphar.2022.952027
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.952027/full


Πέτρα
Α1. Tooth Plaque, Emily Hammerl, in Research Methods in Human Skeletal Biology, 2013
https://www.sciencedirect.com/topics/medicine-and-dentistry/tooth-plaque

Α2. Mali AM, Behal R, Gilda SS. Comparative evaluation of 0.1% turmeric mouthwash with 0.2% chlorhexidine gluconate in prevention of plaque and gingivitis: A clinical and microbiological study. J Indian Soc Periodontol. 2012 Jul;16(3):386-91. doi: 10.4103/0972-124X.100917. PMID: 23162334; PMCID: PMC3498709.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3498709/

Α3. Rathee M, Jain P. Gingivitis. [Updated 2023 Mar 27]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK557422/

Α4. InformedHealth.org [Internet]. Cologne, Germany: Institute for Quality and Efficiency in Health Care (IQWiG); 2006-. Gingivitis and periodontitis: Overview. [Updated 2020 Feb 27]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279593/
https://www.ncbi.nlm.nih.gov/books/NBK279593/

Α5. Parkinson, C.R., Milleman, K.R. & Milleman, J.L. Gingivitis efficacy of a 0.454% w/w stannous fluoride dentifrice: a 24-week randomized controlled trial. BMC Oral Health 20, 89 (2020). https://doi.org/10.1186/s12903-020-01079-6
https://bmcoralhealth.biomedcentral.com/articles/10.1186/s12903-020-01079-6

Α6. Abdulkareem AA, Al-Taweel FB, Al-Sharqi AJB, Gul SS, Sha A, Chapple ILC. Current concepts in the pathogenesis of periodontitis: from symbiosis to dysbiosis. J Oral Microbiol. 2023 Apr 2;15(1):2197779. doi: 10.1080/20002297.2023.2197779. PMID: 37025387; PMCID: PMC10071981.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10071981/

Α7. Karunamoorthi K, Jegajeevanram K, Vijayalakshmi J, Mengistie E. Traditional Medicinal Plants: A Source of Phytotherapeutic Modality in Resource-Constrained Health Care Settings. Journal of Evidence-Based Complementary & Alternative Medicine. 2013;18(1):67-74. doi:10.1177/2156587212460241
https://journals.sagepub.com/doi/10.1177/2156587212460241

Α8. Jeddy N, Ravi S, Radhika T, Sai Lakshmi LJ. Comparison of the efficacy of herbal mouth rinse with commercially available mouth rinses: A clinical trial. J Oral Maxillofac Pathol. 2018 Sep-Dec;22(3):332-334. doi: 10.4103/jomfp.JOMFP_303_18. PMID: 30651676; PMCID: PMC6306595.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306595/

Α9. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/

Α10. Ahmad, Md Faruque. (2018). Ganoderma lucidum: Persuasive biologically active constituents and their health endorsement. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 107. 507-519. 10.1016/j.biopha.2018.08.036.
https://www.sciencedirect.com/science/article/abs/pii/S0753332218326349

Α11. Vazirian M, Faramarzi MA, Ebrahimi SE, Esfahani HR, Samadi N, Hosseini SA, Asghari A, Manayi A, Mousazadeh A, Asef MR, Habibi E, Amanzadeh Y. Antimicrobial effect of the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) and its main compounds. Int J Med Mushrooms. 2014;16(1):77-84. doi: 10.1615/intjmedmushr.v16.i1.70. PMID: 24940906.
https://pubmed.ncbi.nlm.nih.gov/24940906/

Α12. Cör Andrejč D, Knez Ž, Knez Marevci M. Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. PMID: 35935849; PMCID: PMC9353308.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353308/

Α13. Wang X, Lin Z. Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism. Adv Exp Med Biol. 2019;1182:1-37. doi: 10.1007/978-981-32-9421-9_1. PMID: 31777013.
https://pubmed.ncbi.nlm.nih.gov/31777013/

Α14. Kolniak-Ostek J, Oszmiański J, Szyjka A, Moreira H, Barg E. Anticancer and Antioxidant Activities in Ganoderma lucidum Wild Mushrooms in Poland, as Well as Their Phenolic and Triterpenoid Compounds. Int J Mol Sci. 2022 Aug 19;23(16):9359. doi: 10.3390/ijms23169359. PMID: 36012645; PMCID: PMC9408863.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9408863/

Α15. Yuen JW, Gohel MD. Anticancer effects of Ganoderma lucidum: a review of scientific evidence. Nutr Cancer. 2005;53(1):11-7. doi: 10.1207/s15327914nc5301_2. PMID: 16351502.
https://pubmed.ncbi.nlm.nih.gov/16351502/

Α16. G G Saludares et al 2023 IOP Conf. Ser.: Earth Environ. Sci. 1145 012019 DOI 10.1088/1755-1315/1145/1/012019
https://iopscience.iop.org/article/10.1088/1755-1315/1145/1/012019

Α17. Chlorhexidine – pharmacology and clinical applications K. -S. LIM*, P. C. A. KAM, Anaesth Intensive Care 2008; 36: 502-512
https://journals.sagepub.com/doi/pdf/10.1177/0310057X0803600404

Α18. Mathur, Setu & Mathur, Tanu & Srivastava, Rahul & Khatri, Rohit. (2011). Chlorhexidine: The Gold Standard in Chemical Plaque Control. National Journal of Physiology, Pharmacy and Pharmacology. 1.
https://www.researchgate.net/publication/265193587_Chlorhexidine_The_Gold_Standard_in_Chemical_Plaque_Control


Περιοδοντίτιδα
1. Nayak RN, Dixitraj PT, Nayak A, Bhat K. Evaluation of anti-microbial activity of spore powder of Ganoderma lucidum on clinical isolates of Prevotella intermedia: A pilot study. Contemp Clin Dent. 2015 Sep;6(Suppl 1):S248-52. doi: 10.4103/0976-237X.166834. PMID: 26604581; PMCID: PMC4632230.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4632230/


2. Nayak, Aarati & Pt, Dixitraj & Nayak, Ranganath & Bhat, KishoreG. (2021). Comparison of antimicrobial activity of mycelium and spore of Ganoderma Lucidum on Prevotella Intermedia isolated from chronic periodontitis patients. CHRISMED Journal of Health and Research. 8. 35. 10.4103/cjhr.cjhr_61_20.
https://www.researchgate.net/publication/352517315_Comparison_of_antimicrobial_activity_of_mycelium_and_spore_of_Ganoderma_Lucidum_on_Prevotella_Intermedia_isolated_from_chronic_periodontitis_patients

3. Lertpimonchai A, Rattanasiri S, Arj-Ong Vallibhakara S, Attia J, Thakkinstian A. The association between oral hygiene and periodontitis: a systematic review and meta-analysis. Int Dent J. 2017 Dec;67(6):332-343. doi: 10.1111/idj.12317. Epub 2017 Jun 23. PMID: 28646499; PMCID: PMC5724709.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724709/

4. UW researchers reveal new aspects of gum disease and body’s protective response,  Posted on July 6, 2021, University of Washington
https://dental.washington.edu/uw-researchers-reveal-new-aspects-of-gum-disease-and-bodys-protective-response/


Καντιντίαση
1.Talapko J, Juzbašić M, Matijević T, Pustijanac E, Bekić S, Kotris I, Škrlec I. Candida albicans-The Virulence Factors and Clinical Manifestations of Infection. J Fungi (Basel). 2021 Jan 22;7(2):79. doi: 10.3390/jof7020079. PMID: 33499276; PMCID: PMC7912069.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7912069/

2.Patel M. Oral Cavity and Candida albicans: Colonisation to the Development of Infection. Pathogens. 2022 Mar 10;11(3):335. doi: 10.3390/pathogens11030335. PMID: 35335659; PMCID: PMC8953496.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8953496/

3.Mahalingam SS, Jayaraman S, Pandiyan P. Fungal Colonization and Infections-Interactions with Other Human Diseases. Pathogens. 2022 Feb 6;11(2):212. doi: 10.3390/pathogens11020212. PMID: 35215155; PMCID: PMC8875122.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8875122/

4.Taylor M, Brizuela M, Raja A. Oral Candidiasis. [Updated 2023 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK545282/

5.Spectrum of chemo-radiotherapy induced fungal infection in head and neck cancer patients at tertiary care centre of Eastern India, Oral Oncology Reports Volume 6, June 2023, 100039
https://www.sciencedirect.com/science/article/pii/S2772906023000298

6. Antifungal medicines, NHS of UK, 03 April 2023
https://www.nhs.uk/conditions/antifungal-medicines/

7.Revie NM, Iyer KR, Robbins N, Cowen LE. Antifungal drug resistance: evolution, mechanisms and impact. Curr Opin Microbiol. 2018 Oct;45:70-76. doi: 10.1016/j.mib.2018.02.005. Epub 2018 Mar 13. PMID: 29547801; PMCID: PMC6135714.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6135714/

8.National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Long-Term Health and Economic Effects of Antimicrobial Resistance in the United States; Palmer GH, Buckley GJ, editors. Combating Antimicrobial Resistance and Protecting the Miracle of Modern Medicine. Washington (DC): National Academies Press (US); 2021 Oct 20. 3, The Health and Economic Burden of Resistance. Available from: https://www.ncbi.nlm.nih.gov/books/NBK577288/

9.Samuel S. Antwi-Baffour, Ajediran I. Bello, David N. Adjei, Seidu A. Mahmood, Patrick F. Ayeh-Kumi. (2014). The Place of Traditional Medicine in the African Society: The Science, Acceptance and Support. American Journal of Health Research, 2(2), 49-54. https://doi.org/10.11648/j.ajhr.20140202.13
https://www.sciencepublishinggroup.com/article/10.11648/ajhr.20140202.13

10.Bijalwan A, Bahuguna K, Vasishth A, Singh A, Chaudhary S, Dongariyal A, Kumar Thakur T, Kaushik S, Javed Ansari M, Alfarraj S, Ali Alharbi S, Skalicky M, Brestic M. Growth performance of Ganoderma lucidum using billet method in Garhwal Himalaya, India. Saudi J Biol Sci. 2021 May;28(5):2709-2717. doi: 10.1016/j.sjbs.2021.03.030. Epub 2021 Mar 23. PMID: 34025157; PMCID: PMC8117109.
https://www.sciencedirect.com/science/article/pii/S1319562X21002023

11.  Ekiz, E.; Oz, E.; Abd El-Aty, A.M.; Proestos, C.; Brennan, C.; Zeng, M.; Tomasevic, I.; Elobeid, T.; Çadırcı, K.; Bayrak, M.; et al. Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections. Foods 2023, 12, 1512. https://doi.org/10.3390/foods12071512
https://www.mdpi.com/2304-8158/12/7/1512

12. Vazirian M, Faramarzi MA, Ebrahimi SE, Esfahani HR, Samadi N, Hosseini SA, Asghari A, Manayi A, Mousazadeh A, Asef MR, Habibi E, Amanzadeh Y. Antimicrobial effect of the Lingzhi or Reishi medicinal mushroom, Ganoderma lucidum (higher Basidiomycetes) and its main compounds. Int J Med Mushrooms. 2014;16(1):77-84. doi: 10.1615/intjmedmushr.v16.i1.70. PMID: 24940906.
https://pubmed.ncbi.nlm.nih.gov/24940906/

13.Cör Andrejč D, Knez Ž and Knez Marevci M (2022) Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front. Pharmacol. 13:934982. doi: 10.3389/fphar.2022.934982
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.934982/full

14.Mousavi, S.M., Hashemi, S.A., Gholami, A. et al. Ganoderma lucidum methanolic extract as a potent phytoconstituent: characterization, in-vitro antimicrobial and cytotoxic activity. Sci Rep 13, 17326 (2023). https://doi.org/10.1038/s41598-023-44135-1
https://www.nature.com/articles/s41598-023-44135-1

15.Cör Andrejč D, Knez Ž, Knez Marevci M. Antioxidant, antibacterial, antitumor, antifungal, antiviral, anti-inflammatory, and nevro-protective activity of Ganoderma lucidum: An overview. Front Pharmacol. 2022 Jul 22;13:934982. doi: 10.3389/fphar.2022.934982. PMID: 35935849; PMCID: PMC9353308.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9353308/

16.Sánchez-Hernández, E.; Teixeira, A.; Pereira, C.; Cruz, A.; Martín-Gil, J.; Oliveira, R.; Martín-Ramos, P. Chemical Constituents and Antimicrobial Activity of a Ganoderma lucidum (Curtis.) P. Karst. Aqueous Ammonia Extract. Plants 2023, 12, 2271. https://doi.org/10.3390/plants12122271
https://www.mdpi.com/2223-7747/12/12/2271

17.Mustafin, Kairat, Bisko, Nina, Blieva, Raushan, Al-Maali, Galeb, Krupodorova, Tatyana, Narmuratova, Zhanar, Saduyeva, Zhazira and Zhakipbekova, Aigerim. "Antioxidant and antimicrobial potential of Ganoderma lucidum and Trametes versicolor " Turkish Journal of Biochemistry, vol. 47, no. 4, 2022, pp. 483-489. https://doi.org/10.1515/tjb-2021-0141
https://www.degruyter.com/document/doi/10.1515/tjb-2021-0141/html

18.Ahmad, Md Faruque & Alsayegh, Abdulrahman & Ahmad, Fakhruddin & Akhtar, Md Sayeed & S.Alavudeen, Sirajudeen & Bantun, Farkad & Ahmed, Awais & Ali, M. & Elbendary, Ehab & Raposo, Antonio & Kambal, Nahla & Abdelrahman, Mohamed. (2024). Ganoderma lucidum: Insight into antimicrobial and antioxidant properties with development of secondary metabolites. Heliyon. e25607. 10.1016/j.heliyon.2024.e25607.
https://www.sciencedirect.com/science/article/pii/S2405844024016384

19.G G Saludares et al 2023 IOP Conf. Ser.: Earth Environ. Sci. 1145 012019
https://iopscience.iop.org/article/10.1088/1755-1315/1145/1/012019

20. Erbiai EH, Amina B, Kaoutar A, Saidi R, Lamrani Z, Pinto E, Esteves da Silva JCG, Maouni A, Pinto da Silva L. Chemical Characterization and Evaluation of Antimicrobial Properties of the Wild Medicinal Mushroom Ganoderma lucidum Growing in Northern Moroccan Forests. Life. 2023; 13(5):1217. https://doi.org/10.3390/life13051217
https://www.mdpi.com/2075-1729/13/5/1217

21. Evaluation of Antifungal Effectiveness of a Novel Probiotic Toothpaste: An In-vitro Study, Pavita Kataria1, HarPreet SingH2, DOI: 10.7860/JCDR/2022/55875.16752
https://www.jcdr.net/articles/PDF/16752/55875_CE[Nik]_F(KR)_PF1(RD_SS)_PFA(RD_KM)_PN(KM).pdf

22.Berdicevsky I, Ben-Aryeh H, Szargel R, Gutman D. Oral Candida in children. Oral Surg Oral Med Oral Pathol. 1984 Jan;57(1):37-40. doi: 10.1016/0030-4220(84)90257-3. PMID: 6582432.
https://pubmed.ncbi.nlm.nih.gov/6582432/

23.Arendorf TM, Walker DM. The prevalence and intra-oral distribution of Candida albicans in man. Arch Oral Biol. 1980;25(1):1-10. doi: 10.1016/0003-9969(80)90147-8. PMID: 6996654.
https://www.sciencedirect.com/science/article/abs/pii/0003996980901478

24.Jerônimo LS, Esteves Lima RP, Suzuki TYU, Discacciati JAC, Bhering CLB. Oral Candidiasis and COVID-19 in Users of Removable Dentures: Is Special Oral Care Needed? Gerontology. 2022;68(1):80-85. doi: 10.1159/000515214. Epub 2021 Apr 14. PMID: 33853063; PMCID: PMC8089415.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8089415/

25.Cumming CG, Wight C, Blackwell CL, Wray D. Denture stomatitis in the elderly. Oral Microbiol Immunol. 1990 Apr;5(2):82-5. doi: 10.1111/j.1399-302x.1990.tb00232.x. PMID: 2087353.
https://pubmed.ncbi.nlm.nih.gov/2087353/

26. Rodu B, Carpenter JT, Jones MR. The pathogenesis and clinical significance of cytologically detectable oral Candida in acute leukemia. Cancer. 1988 Nov 1;62(9):2042-6. doi: 10.1002/1097-0142(19881101)62:9<2042::aid-cncr2820620928>3.0.co;2-d. PMID: 3167816.
https://pubmed.ncbi.nlm.nih.gov/3167816/

27.Erfaninejad M, Zarei Mahmoudabadi A, Maraghi E, Hashemzadeh M, Fatahinia M. Epidemiology, prevalence, and associated factors of oral candidiasis in HIV patients from southwest Iran in post-highly active antiretroviral therapy era. Front Microbiol. 2022 Sep 2;13:983348. doi: 10.3389/fmicb.2022.983348. PMID: 36118210; PMCID: PMC9478364.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478364/

28.Cheng MF, Yang YL, Yao TJ, Lin CY, Liu JS, Tang RB, Yu KW, Fan YH, Hsieh KS, Ho M, Lo HJ. Risk factors for fatal candidemia caused by Candida albicans and non-albicans Candida species. BMC Infect Dis. 2005 Apr 7;5:22. doi: 10.1186/1471-2334-5-22. PMID: 15813977; PMCID: PMC1090575.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090575/

29.Wenzel RP. Nosocomial candidemia: risk factors and attributable mortality. Clin Infect Dis. 1995 Jun;20(6):1531-4. doi: 10.1093/clinids/20.6.1531. PMID: 7548504.
https://pubmed.ncbi.nlm.nih.gov/7548504/

30.Nikawa H, Hamada T, Yamamoto T. Denture plaque--past and recent concerns. J Dent. 1998 May;26(4):299-304. doi: 10.1016/s0300-5712(97)00026-2. PMID: 9611934.
https://pubmed.ncbi.nlm.nih.gov/9611934/

31. Nayak, Aarati & Nayak, Ranganath & Bhat, Kishore. (2010). Antifungal activity of a toothpaste containing Ganoderma lucidum against Candida albicans - an in vitro study. J Int Oral Health. 2.
https://www.researchgate.net/publication/265021444_Antifungal_activity_of_a_toothpaste_containing_Ganoderma_lucidum_against_Candida_albicans_-_an_in_vitro_study
https://www.ispcd.org/userfiles/rishabh/jioh-02-02-051_2.pdf


Στηθάγχη
1. Cardiovascular diseases, World Health Organization
https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1

2. British Heart Foundation, Global Heart & Circulatory Diseases Factsheet, January 2024
https://www.bhf.org.uk/-/media/files/for-professionals/research/heart-statistics/bhf-cvd-statistics-global-factsheet.pdf?rev=e61c05db17e9439a8c2e4720f6ca0a19&hash=6350DE1B2A19D939431D876311077C7B

3. Pahwa R, Jialal I. Atherosclerosis. [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507799/
https://www.ncbi.nlm.nih.gov/books/NBK507799/

4. Effects of statins beyond lipid lowering: Potential for clinical benefits  Khalid Almuti, ... Robert J. Ostfeld, in International Journal of Cardiology, 2006
https://www.sciencedirect.com/topics/medicine-and-dentistry/endothelial-dysfunction

5. Adarsh Ray, Krushna Ch. Maharana, Sarasa Meenakshi, Sanjiv Singh, Endothelial dysfunction and its relation in different disorders: Recent update, Health Sciences Review, Volume 7, 2023, 100084, ISSN 2772-6320, https://doi.org/10.1016/j.hsr.2023.100084.
https://www.sciencedirect.com/science/article/pii/S2772632023000107

6. Stable angina, Icahn School of Medicine at Mount Sinai
https://www.mountsinai.org/health-library/diseases-conditions/stable-angina

7. Angina Pectoris (Stable Angina), American Heart Association, Dec 5, 2022
https://www.heart.org/en/health-topics/heart-attack/angina-chest-pain/angina-pectoris-stable-angina

8. Stable angina, National Library of Medicine, USA, 1/1/2023
https://medlineplus.gov/ency/article/000198.htm

9. Angina, NHS, UK, 22 April 2021
https://www.nhs.uk/conditions/angina/

10. Andrikopoulos G, Parissis J, Filippatos G, Nikolaou M, Pantos K, Voudris V, Karvounis H, Alexopoulos D, Goudevenos J. Medical management of stable angina. Hellenic J Cardiol. 2014 Jul-Aug;55(4):272-80. PMID: 25039022.
https://www.hellenicjcardiol.org/archive/full_text/2014/4/2014_4_272.pdf

11. Wachtel-Galor S, Yuen J, Buswell JA, et al. Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 9. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/
https://www.ncbi.nlm.nih.gov/books/NBK92757/

12. Ekiz E, Oz E, Abd El-Aty AM, Proestos C, Brennan C, Zeng M, Tomasevic I, Elobeid T, Çadırcı K, Bayrak M, Oz F. Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections. Foods. 2023 Apr 3;12(7):1512. doi: 10.3390/foods12071512. PMID: 37048331; PMCID: PMC10094145.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10094145/

13. Cai Z, Wong CK, Dong J, Jiao D, Chu M, Leung PC, Lau CBS, Lau CP, Tam LS, Lam CWK. Anti-inflammatory activities of Ganoderma lucidum (Lingzhi) and San-Miao-San supplements in MRL/lpr mice for the treatment of systemic lupus erythematosus. Chin Med. 2016 Apr 29;11:23. doi: 10.1186/s13020-016-0093-x. PMID: 27134645; PMCID: PMC4851790.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4851790/

14. Cao Y, Xu X, Liu S, Huang L and Gu J (2018) Ganoderma: A Cancer Immunotherapy Review. Front. Pharmacol. 9:1217. doi: 10.3389/fphar.2018.01217
https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2018.01217/full

15.  Sargowo D, Ovianti N, Susilowati E, et al. The role of polysaccharide peptide of Ganoderma lucidum as a potent antioxidant against atherosclerosis in high risk and stable angina patients. Indian Heart Journal. 2018 Sep - Oct;70(5):608-614. DOI: 10.1016/j.ihj.2017.12.007. PMID: 30392496; PMCID: PMC6204443.
https://europepmc.org/article/MED/30392496

16. Younus H. Therapeutic potentials of superoxide dismutase. Int J Health Sci (Qassim). 2018 May-Jun;12(3):88-93. PMID: 29896077; PMCID: PMC5969776.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5969776/

17. Oxidative Stress and Inflammation in Schizophrenia  Minori Koga, ... Thomas W. Sedlak, in Schizophrenia Research, 2016
https://www.sciencedirect.com/topics/neuroscience/superoxide-dismutase

18. Zheng M, Liu Y, Zhang G, Yang Z, Xu W, Chen Q. The Applications and Mechanisms of Superoxide Dismutase in Medicine, Food, and Cosmetics. Antioxidants (Basel). 2023 Aug 27;12(9):1675. doi: 10.3390/antiox12091675. PMID: 37759978; PMCID: PMC10525108.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10525108/

19. Circulating malondialdehyde level in patients with epilepsy: A meta-analysis  Huaiyu Sun, ... Hongmei Meng, in Seizure: European Journal of Epilepsy, 2022
https://www.sciencedirect.com/topics/medicine-and-dentistry/malonaldehyde

20. Gaweł S, Wardas M, Niedworok E, Wardas P. Dialdehyd malonowy (MDA) jako wskaźnik procesów peroksydacji lipidów w organizmie [Malondialdehyde (MDA) as a lipid peroxidation marker]. Wiad Lek. 2004;57(9-10):453-5. Polish. PMID: 15765761.
https://pubmed.ncbi.nlm.nih.gov/15765761/

21.Daniele Del Rio, Amanda J. Stewart, Nicoletta Pellegrini, A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress, Nutrition, Metabolism and Cardiovascular Diseases, Volume 15, Issue 4, 2005, Pages 316-328, ISSN 0939-4753, https://doi.org/10.1016/j.numecd.2005.05.003.
https://www.sciencedirect.com/science/article/abs/pii/S0939475305001043

22. Etiology and pathogenesis of systemic sclerosis  John Varga, Robert Lafyatis, in Rheumatology (Sixth Edition), 2015
https://www.sciencedirect.com/topics/medicine-and-dentistry/circulating-endothelial-cell

23. Erdbruegger U, Dhaygude A, Haubitz M, Woywodt A. Circulating endothelial cells: markers and mediators of vascular damage. Curr Stem Cell Res Ther. 2010 Dec;5(4):294-302. doi: 10.2174/157488810793351721. PMID: 20528750.
https://pubmed.ncbi.nlm.nih.gov/20528750/

24. Farinacci M, Krahn T, Dinh W, Volk HD, Düngen HD, Wagner J, Konen T, von Ahsen O. Circulating endothelial cells as biomarker for cardiovascular diseases. Res Pract Thromb Haemost. 2018 Oct 26;3(1):49-58. doi: 10.1002/rth2.12158. PMID: 30656276; PMCID: PMC6332781.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332781/

25. Fujisawa T, Tura-Ceide O, Hunter A, Mitchell A, Vesey A, Medine C, Gallogly S, Hadoke PWF, Keith C, Sproul A, Roddie H, McQuaker G, Wilmut I, Mills NL, Brittan M. Endothelial Progenitor Cells Do Not Originate From the Bone Marrow. Circulation. 2019 Oct 29;140(18):1524-1526. doi: 10.1161/CIRCULATIONAHA.119.042351. Epub 2019 Oct 28. PMID: 31657952; PMCID: PMC6818974.
https://www.ahajournals.org/doi/full/10.1161/CIRCULATIONAHA.119.042351

26.  Ayala A, Muñoz MF, Argüelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxidative Medicine and Cellular Longevity. 2014 ;2014:360438. DOI: 10.1155/2014/360438. PMID: 24999379; PMCID: PMC4066722.
https://europepmc.org/article/PMC/4066722




Στεφανιαία νόσος
Gao, Yihuai & Lan, Jin & Dai, Xihu & Ye, Jingxian & Zhou, Shufeng. (2004). A Phase I/II Study of Ling Zhi Mushroom Ganoderma lucidum (W.Curt.:Fr.)Lloyd (Aphyllophoromycetideae) Extract in Patients with Type II Diabetes Mellitus. International Journal of Medicinal Mushrooms - INT J MED MUSHROOMS. 6. 33-40. 10.1615/IntJMedMushr.v6.i1.30.
https://www.dl.begellhouse.com/journals/708ae68d64b17c52,0351bdaa3d2241c0,3d8418037d39d507.html



Σχιζοφρένεια
1. Schizophrenia 10 January 2022, WHO
https://www.who.int/news-room/fact-sheets/detail/schizophrenia

2. Picchioni MM, Murray RM. Schizophrenia. BMJ. 2007 Jul 14;335(7610):91-5. doi: 10.1136/bmj.39227.616447.BE. PMID: 17626963; PMCID: PMC1914490.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1914490/

3. National Institute of Mental Health (NIMH), Schizophrenia
https://www.nimh.nih.gov/health/statistics/schizophrenia

4. U.S. Department of Health & Human Services, Schizophrenia, 04/24/2023
https://www.samhsa.gov/mental-health/schizophrenia

5. What is Schizophrenia?, American Psychiatric Association
https://www.psychiatry.org/patients-families/schizophrenia/what-is-schizophrenia

6. Schizophrenia  By Carol Tamminga  , MD, UT Southwestern Medical Dallas Reviewed/Revised Apr 2022 | Modified Sep 2022
https://www.msdmanuals.com/professional/psychiatric-disorders/schizophrenia-and-related-disorders/schizophrenia

7. Mental Health By the Numbers, National Alliance on Mental Illness
https://www.nami.org/mhstats

8. Inanaga K (2015) Recovery from Schizophrenia with Bioactive Substances in Hericium erinaceum. Int J Sch Cog Psychol S1:003
https://www.longdom.org/open-access/recovery-from-schizophrenia-with-bioactive-substances-in-hericium-erinaceum-22259.html

9. The Power of the Lion's Mane Mushroom: Regenerate Your Brain With Lion's Mane Edición Kindle de Ward W. Bond Ph.D. (Author), Ken Babal (Author)
https://www.amazon.com/Power-Lions-Mane-Mushroom-Regenerate-ebook/dp/B07122GLYW

10. The Secret to the Lion's Mane Mushroom, 6/9/2014, Ward W. Bond, PhD
https://www.drwardbond.com/dr-bs-blog/the-secret-to-the-lions-mane-mushroom

11.  Case Report Open Access Case Report: Recovery from Schizophrenia Using Amyloban 3399, Compounds Extracted from Hericium erinaceum  Kazutoyo Inanaga MD, PhD*
https://www.omicsonline.org/open-access/case-report-recovery-from-schizophrenia-using-amyloban-compounds-extracted-from-hericium-erinaceum-1522-4821-17-141.php?aid=33887

12. Inanaga, Kazutoyo et al. “Improvement of refractory schizophrenia on using Amyloban®3399 extracted from Hericium erinaceum.” Personalized Medicine Universe 3 (2014): 49-53.
https://www.sciencedirect.com/science/article/abs/pii/S2186495014000145

13. Cortonesi, Pietra & Almeida, Laura & Pinheiro, Rafael & Périco, Cintia & Castaldelli-Maia, João. (2023). Use of Hericium erinaceus as a potential therapeutic of mental disorders: a systematic review. Debates em Psiquiatria. 13. 1-13. 10.25118/2763-9037.2023.v13.443.
https://www.researchgate.net/publication/368465770_Use_of_Hericium_erinaceus_as_a_potential_therapeutic_of_mental_disorders_a_systematic_review

14. National Library of Medicine, 2/6/2023, Pubmed
https://pubmed.ncbi.nlm.nih.gov/?term=hericium+OR+lion%27s+mane&size=200

15. Tripathi A, Kar SK, Shukla R. Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies. Clin Psychopharmacol Neurosci. 2018 Feb 28;16(1):7-17. doi: 10.9758/cpn.2018.16.1.7. PMID: 29397662; PMCID: PMC5810454.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810454/

16. Phytother Res, 23 (3), 367-72 Mar 2009 Improving Effects of the Mushroom Yamabushitake (Hericium Erinaceus) on Mild Cognitive Impairment: A Double-Blind Placebo-Controlled Clinical Trial Koichiro Mori, Satoshi Inatomi, Kenzi Ouchi, Yoshihito Azumi, Takashi Tuchida
https://pubmed.ncbi.nlm.nih.gov/18844328

17. Introduction, Consortium for Globalization of Chinese Medicine (CGCM)
http://www.tcmedicine.org/page.php?id=124

18. Poria cocos, Dec 17, 2019, Consortium for Globalization of Chinese Medicine (CGCM)
http://www.tcmedicine.org/article.php?id=381



Ώριμη Ηλικία
1. American Physiological Society, 2004 - Derivatives of a rare Chinese mushroom can improve capacity for aerobic exercise and endurance in the mid-age to elderly, sedentary humans

2. Βιβλίο του Shawn M. Talbott, Ph.D. Ένας οδηγός για την κατανόηση των συμπληρωμάτων διατροφής.

3. Yi, Xiao & Xi-zhen, Huang & Zhu, Jia-Shi. (2004). Randomized double-blind placebo-controlled clinical trial and assessment of fermentation product of Cordyceps sinensis (Cs4) in enhancing aerobic capacity and respiratory function of the healthy elderly volunteers. Chinese Journal of Integrative Medicine - CHIN J INTEGR MED. 10. 187-192. 10.1007/BF02836405.
https://link.springer.com/article/10.1007/BF02836405
https://www.researchgate.net/publication/246146225_Randomized_double-blind_placebo-controlled_clinical_trial_and_assessment_of_fermentation_product_of_Cordyceps_sinensis_Cs4_in_enhancing_aerobic_capacity_and_respiratory_function_of_the_healthy_elderly

4. Chen S, Li Z, Krochmal R, Abrazado M, Kim W, Cooper CB. Effect of Cs-4 (Cordyceps sinensis) on exercise performance in healthy older subjects: a double-blind, placebo-controlled trial. J Altern Complement Med. 2010 May;16(5):585-90. doi: 10.1089/acm.2009.0226. PMID: 20804368; PMCID: PMC3110835.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110835/